| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rhonda P Patrick, Bruce N Ame. Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 6. 2015-08-24. PMID:25713056. |
we propose mechanisms by which epa increases serotonin release from presynaptic neurons by reducing e2 series prostaglandins and dha influences serotonin receptor action by increasing cell membrane fluidity in postsynaptic neurons. |
2015-08-24 |
2023-08-13 |
Not clear |
| Mousumi Ghosh, Damien D Pears. The role of the serotonergic system in locomotor recovery after spinal cord injury. Frontiers in neural circuits. vol 8. 2015-07-30. PMID:25709569. |
these strategies have included pharmacological modulation of serotonergic receptors, through the administration of specific 5-ht receptor agonists, or by elevating the 5-ht precursor 5-hydroxytryptophan, which produces a global activation of all classes of 5-ht receptors. |
2015-07-30 |
2023-08-13 |
Not clear |
| David Matuskey, Zubin Bhagwagar, Beata Planeta, Brian Pittman, Jean-Dominique Gallezot, Jason Chen, Jane Wanyiri, Soheila Najafzadeh, Jim Ropchan, Paul Geha, Yiyun Huang, Marc N Potenza, Alexander Neumeister, Richard E Carson, Robert T Maliso. Reductions in brain 5-HT1B receptor availability in primarily cocaine-dependent humans. Biological psychiatry. vol 76. issue 10. 2015-07-27. PMID:24433854. |
preclinical evidence implicates the serotonin receptor 5-hydroxytryptamine 1b (5-ht1b) in the effects of cocaine. |
2015-07-27 |
2023-08-12 |
human |
| Mônica Lopes-Ferreira, Eduardo Martins Gomes, Fernanda Miriani Bruni, Marcio Jose Ferreira, Patrícia Charvet, Carla Lim. First report of interruption of mast cell degranulation and endothelial cells activation by anti-inflammatory drugs controlling the acute response provoked by Pseudoplatystoma fasciatum fish venom. Toxicon : official journal of the International Society on Toxinology. vol 90. 2015-06-25. PMID:25152168. |
we found that serotonin, leukotrine and prostaglandin are involved in edematogenic and nociceptive responses, since a selective cox-2 inhibitor, a non-specific inhibitor for cytokines and cox-2, and a non-selective 5-ht receptor antagonist were able to reduce both symptoms. |
2015-06-25 |
2023-08-13 |
mouse |
| Hong-Yan Qin, Chung-Wah Cheng, Xu-Dong Tang, Zhao-Xiang Bia. Impact of psychological stress on irritable bowel syndrome. World journal of gastroenterology. vol 20. issue 39. 2015-06-24. PMID:25339801. |
now, non-pharmacological approaches and pharmacological strategies that target on stress-related alterations, such as antidepressants, antipsychotics, miscellaneous agents, 5-ht synthesis inhibitors, selective 5-ht reuptake inhibitors, and specific 5-ht receptor antagonists or agonists have shown a critical role in ibs management. |
2015-06-24 |
2023-08-13 |
Not clear |
| B N Manukhin, L A Nesterov. [Allosteric effect of serotonin and mianserin on the kinetics of specific [3H]-ligand binding to adrenergic and muscarinic receptors in the rat cerebral cortex membranes]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 2. 2015-06-24. PMID:26021159. |
the effects of serotonin receptor activation (by serotonin) and inhibition (by mianserin) on the properties of the α1-, α2-adrenoreceptors, and muscarinic cholinergic receptors in subcellular membrane fractions from the rat cerebral cortex were studied. |
2015-06-24 |
2023-08-13 |
rat |
| Christopher S Reigstad, Charles E Salmonson, John F Rainey, Joseph H Szurszewski, David R Linden, Justin L Sonnenburg, Gianrico Farrugia, Purna C Kashya. Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 4. 2015-06-22. PMID:25550456. |
microbiota from hm and conventionally raised (cr) mice significantly increased colonic mrnas tph1 [(tryptophan hydroxylase) 1, rate limiting for mucosal 5-ht synthesis; p < 0.01] and chromogranin a (neuroendocrine secretion; p < 0.01), with no effect on monoamine oxidase a (serotonin catabolism), serotonin receptor 5-ht4, or mouse serotonin transporter. |
2015-06-22 |
2023-08-13 |
mouse |
| Leonard L Howell, Kathryn A Cunningha. Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder. Pharmacological reviews. vol 67. issue 1. 2015-06-15. PMID:25505168. |
5-ht receptors are widely expressed throughout the brain, and several different 5-ht receptor subtypes have been implicated in mediating the effects of endogenous 5-ht on da. |
2015-06-15 |
2023-08-13 |
Not clear |
| Zheng-Quan Tang, Laurence O Trussel. Serotonergic regulation of excitability of principal cells of the dorsal cochlear nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 11. 2015-06-15. PMID:25788672. |
using a combination of in vitro electrophysiology and optogenetics in mouse brain slices, we found that 5-ht directly enhances the excitability of fusiform principal cells via activation of two distinct 5-ht receptor subfamilies, 5-ht2a/2cr (5-ht2a/2c receptor) and 5-ht7r (5-ht7 receptor). |
2015-06-15 |
2023-08-13 |
mouse |
| Robin L Davisson, James N Bates, Alan Kim Johnson, Stephen J Lewi. Effects of intracerebroventricular injections of 5-HT on systemic vascular resistances of conscious rats. Microvascular research. vol 95. 2015-06-11. PMID:25128748. |
injections of 5-hydroxytryptamine (5-ht, 10μg) on mean arterial blood pressure (map), heart rate (hr) and mesenteric (mr), renal (rr) and hindquarter (hqr) vascular resistances of conscious rats, (ii) the central 5-ht receptor subtype which mediates these effects, and (iii) the role of nitric oxide (no) in the expression of these responses. |
2015-06-11 |
2023-08-13 |
rat |
| April Johnston, Chris J McBain, André Fisah. 5-Hydroxytryptamine1A receptor-activation hyperpolarizes pyramidal cells and suppresses hippocampal gamma oscillations via Kir3 channel activation. The Journal of physiology. vol 592. issue 19. 2015-06-10. PMID:25107925. |
multiple 5-ht receptor subtypes are expressed in the ca3 region of the hippocampus and high doses of 5-ht reduce the power of induced gamma oscillations.hypothesizing that 5-ht may have cell- and receptor subtype-specific modulatory effects, we investigated the receptor subtypes, cell types and cellular mechanisms engaged by 5-ht in the modulation of gamma oscillations in mice and rats. |
2015-06-10 |
2023-08-13 |
mouse |
| Jean-Paul V Paluzzi, Garima Bhatt, Chang-Hui J Wang, Meet Zandawala, Angela B Lange, Ian Orchar. Identification, functional characterization, and pharmacological profile of a serotonin type-2b receptor in the medically important insect, Rhodnius prolixus. Frontiers in neuroscience. vol 9. 2015-06-04. PMID:26041983. |
rhopr5htr2b is sensitive to alpha-methyl serotonin and is inhibited by a variety of serotonin receptor antagonists, including propranolol, spiperone, ketanserin, mianserin, and cyproheptadine. |
2015-06-04 |
2023-08-13 |
Not clear |
| Qi Wang, Maoxian H. Molecular characterization and analysis of a putative 5-HT receptor involved in reproduction process of the pearl oyster Pinctada fucata. General and comparative endocrinology. vol 204. 2015-04-23. PMID:24852353. |
to gain a better understanding of the effects of 5-ht on developmental regulation in the pearl oyster pinctada fucata, the isolation, cloning, and expression of the 5-ht receptor was investigated in this study. |
2015-04-23 |
2023-08-13 |
aplysia |
| Nur Iwani A Rozak, Imran Ahmad, Siew Hua Gan, Ruzilawati Abu Baka. Lack of Association between the Serotonin Transporter (5-HTT) and Serotonin Receptor (5-HT2A) Gene Polymorphisms with Smoking Behavior among Malaysian Malays. Scientia pharmaceutica. vol 82. issue 3. 2015-04-08. PMID:25853073. |
lack of association between the serotonin transporter (5-htt) and serotonin receptor (5-ht2a) gene polymorphisms with smoking behavior among malaysian malays. |
2015-04-08 |
2023-08-13 |
Not clear |
| Yi-Xiang Qi, Ren-Ying Xia, Ya-Su Wu, David Stanley, Jia Huang, Gong-Yin Y. Larvae of the small white butterfly, Pieris rapae, express a novel serotonin receptor. Journal of neurochemistry. vol 131. issue 6. 2015-03-06. PMID:25187179. |
after heterologous expression in hek293 cells, pr5-ht8 mediated increased [ca(2+)]i in response to low concentrations (< 10 nm) of 5-ht and various 5-ht receptor agonists. |
2015-03-06 |
2023-08-13 |
drosophila_melanogaster |
| Christine Saunders, Michael Siuta, Sabrina D Robertson, Adeola R Davis, Jennifer Sauer, Heinrich J G Matthies, Paul J Gresch, David Airey, Craig W Lindsley, John A Schetz, Kevin D Niswender, Jeremy M Veenstra-Vanderweele, Aurelio Gall. Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function. Neurochemistry international. vol 73. 2015-02-02. PMID:24090638. |
these data reveal that defective central akt function alters 5-ht signaling as well as 5-ht-associated behaviors, demonstrating a novel role for akt in maintaining neuronal 5-ht receptor function. |
2015-02-02 |
2023-08-12 |
mouse |
| Aki Takahashi, Isabel M Quadros, Rosa M M de Almeida, Klaus A Micze. Behavioral and pharmacogenetics of aggressive behavior. Current topics in behavioral neurosciences. vol 12. 2015-01-20. PMID:22297576. |
impaired regulation of each subtype of 5-ht receptor, 5-ht transporter, synthetic and metabolic enzymes has been linked particularly to impulsive aggression. |
2015-01-20 |
2023-08-12 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
whereas, chronic cor (20, 40 mg/kg) treatments reversed the behavioral deficiency induced by cums exposure, treatment with cor normalized the change of tnf-α, il-6, 5-ht, and ne levels, which demonstrated that cor could partially restore cums-induced 5-ht receptor impairments and inflammation. |
2015-01-14 |
2023-08-13 |
mouse |
| C Selli, Y Erac, M Tosu. Cyclopiazonic acid alters serotonin-induced responses in rat thoracic aorta. Vascular pharmacology. vol 61. issue 2-3. 2015-01-02. PMID:24704610. |
since serotonin (5-hydroxytryptamine, 5-ht) receptors are reported to be localized on caveolar membranes, we investigated whether serca inhibition affects 5-ht-induced responses and 5-ht receptor antagonism. |
2015-01-02 |
2023-08-13 |
rat |
| C Selli, Y Erac, M Tosu. Cyclopiazonic acid alters serotonin-induced responses in rat thoracic aorta. Vascular pharmacology. vol 61. issue 2-3. 2015-01-02. PMID:24704610. |
furthermore, non-selective 5-ht receptor blocker methysergide partially inhibited cpa-induced 5-ht contractions. |
2015-01-02 |
2023-08-13 |
rat |