| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gitte M Knudsen, Peter S Jensen, David Erritzoe, William F C Baaré, Anders Ettrup, Patrick M Fisher, Nic Gillings, Hanne D Hansen, Lars Kai Hansen, Steen G Hasselbalch, Susanne Henningsson, Matthias M Herth, Klaus K Holst, Pernille Iversen, Lars V Kessing, Julian Macoveanu, Kathrine Skak Madsen, Erik L Mortensen, Finn Årup Nielsen, Olaf B Paulson, Hartwig R Siebner, Dea S Stenbæk, Claus Svarer, Terry L Jernigan, Stephen C Strother, Vibe G Frokjae. The Center for Integrated Molecular Brain Imaging (Cimbi) database. NeuroImage. vol 124. issue Pt B. 2016-09-06. PMID:25891375. |
the data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-ht1a, 5-ht1b, 5-ht2a, and 5-ht4 and the 5-ht transporter (5-htt), but can easily serve other purposes. |
2016-09-06 |
2023-08-13 |
human |
| b' Ra\\xc3\\xbal Pe\\xc3\\xb1as-Cazorla, M Teresa Vilar\\xc3\\xb. Serotonin 5-HT4 receptors and forebrain cholinergic system: receptor expression in identified cell populations. Brain structure & function. vol 220. issue 6. 2016-06-15. PMID:25183542.' |
serotonin 5-ht4 receptors and forebrain cholinergic system: receptor expression in identified cell populations. |
2016-06-15 |
2023-08-13 |
rat |
| b' Ra\\xc3\\xbal Pe\\xc3\\xb1as-Cazorla, M Teresa Vilar\\xc3\\xb. Serotonin 5-HT4 receptors and forebrain cholinergic system: receptor expression in identified cell populations. Brain structure & function. vol 220. issue 6. 2016-06-15. PMID:25183542.' |
activation of serotonin 5-ht4 receptors has pro-cognitive effects on memory performance. |
2016-06-15 |
2023-08-13 |
rat |
| Katsunori Nonogaki, Takao Kaj. Mosapride, a selective serotonin 5-HT4 receptor agonist, and alogliptin, a selective dipeptidyl peptidase-4 inhibitor, exert synergic effects on plasma active GLP-1 levels and glucose tolerance in mice. Diabetes research and clinical practice. vol 110. issue 3. 2016-06-09. PMID:26497774. |
mosapride, a selective serotonin 5-ht4 receptor agonist, and alogliptin, a selective dipeptidyl peptidase-4 inhibitor, exert synergic effects on plasma active glp-1 levels and glucose tolerance in mice. |
2016-06-09 |
2023-08-13 |
mouse |
| Katsunori Nonogaki, Takao Kaj. Mosapride, a selective serotonin 5-HT4 receptor agonist, and alogliptin, a selective dipeptidyl peptidase-4 inhibitor, exert synergic effects on plasma active GLP-1 levels and glucose tolerance in mice. Diabetes research and clinical practice. vol 110. issue 3. 2016-06-09. PMID:26497774. |
pharmacologic stimulation of serotonin 5-ht4 receptors increased plasma active glucagon-like-peptide-1 (glp-1) levels independent of feeding, and that pharmacologic stimulation of 5-ht4 receptors and pharmacologic inhibition of dipeptidyl peptidase-4 exerted synergic effects on plasma active glp-1 levels and glucose tolerance in mice. |
2016-06-09 |
2023-08-13 |
mouse |
| T Amano, H Ariga, A Kurematsu, S Yamato, S Morioka, A Masaka, M Kanazawa, S Fukud. Effect of 5-hydroxytryptamine receptor 4 agonist mosapride on human gastric accommodation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 27. issue 9. 2016-05-25. PMID:26303048. |
mosapride citrate is a 5-hydroxytryptamine receptor 4 (5-ht4) agonist, which is shown to improve upper abdominal symptoms. |
2016-05-25 |
2023-08-13 |
human |
| Tetsuya Imamura, Osamu Ishizuka, Teruyuki Ogawa, Tomonori Minagawa, Masakuni Ishikawa, Shiro Hiragata, Hitoshi Yokoyama, Masaki Nakazawa, Yoshiki Kurizaki, Osamu Nishizaw. Expression of 5-Hydroxytryptamine Receptors in Human Urinary Bladders with Benign Prostatic Hyperplasia. Advances in therapy. vol 32 Suppl 1. 2016-05-25. PMID:26391373. |
this study investigated the mrna expression pattern and distribution of 5-hydroxytryptamine (5-ht) receptors 5-ht2a, 5-ht2b, 5-ht3a, 5-ht4, and 5-ht7 within the urothelium and detrusor of normal bladder tissue and in the urothelium of bladders from patients with benign prostatic hyperplasia (bph). |
2016-05-25 |
2023-08-13 |
human |
| Kei Goto, Isao Kawahara, Hiroki Kuniyasu, Miyako Takak. A protein tyrosine kinase receptor, c-RET signaling pathway contributes to the enteric neurogenesis induced by a 5-HT4 receptor agonist at an anastomosis after transection of the gut in rodents. The journal of physiological sciences : JPS. vol 65. issue 4. 2016-04-22. PMID:25850922. |
we previously reported that a serotonin 4 (5-ht4) receptor agonist, mosapride citrate (mos), increased the number of c-ret-positive cells and levels of c-ret mrna in gel sponge implanted in the necks of rats. |
2016-04-22 |
2023-08-13 |
rat |
| Patrick MacDonald Fisher, Mette Ewers Haahr, Christian Gaden Jensen, Vibe Gedsoe Frokjaer, Hartwig Roman Siebner, Gitte Moos Knudse. Fluctuations in [¹¹C]SB207145 PET binding associated with change in threat-related amygdala reactivity in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 6. 2016-03-29. PMID:25560201. |
recently, we showed in a placebo-controlled study of 32 healthy males that brain serotonin 4 receptor (5-ht4) binding, assessed with [(11)c]sb207145 pet, was sensitive to a 3-week intervention with the selective serotonin reuptake inhibitor fluoxetine, supporting it as an in vivo model for fluctuations in central serotonin levels. |
2016-03-29 |
2023-08-13 |
human |
| D M Kendig, J R Gride. Serotonin and colonic motility. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 27. issue 7. 2016-03-23. PMID:26095115. |
many studies suggest that 5-ht is important to normal and dysfunctional gut motility and drugs affecting 5-ht receptors, especially 5-ht3 and 5-ht4 receptors, have been used clinically to treat motility disorders; however, cardiovascular side effects have limited the use of these drugs. |
2016-03-23 |
2023-08-13 |
rat |
| Urszula Stępińska, Takashi Kuwana, Bożenna Olszańsk. Serotonin receptors are selectively expressed in the avian germ cells and early embryos. Zygote (Cambridge, England). vol 23. issue 3. 2016-03-15. PMID:24521994. |
the expression of nine serotonin (5-ht) receptor transcripts was studied using reverse transcription polymerase chain reaction (rt-pcr) in germ cells, cleavage and gastrulation stages of japanese quail, and qpcr for 5-ht3 and 5-ht4 receptors in oocytes and embryos. |
2016-03-15 |
2023-08-12 |
Not clear |
| Urszula Stępińska, Takashi Kuwana, Bożenna Olszańsk. Serotonin receptors are selectively expressed in the avian germ cells and early embryos. Zygote (Cambridge, England). vol 23. issue 3. 2016-03-15. PMID:24521994. |
we show the presence/absence of nine serotonin transcripts known in birds for receptors 5-ht1a, 5-ht1f, 5-ht2b, 5-ht2c, 5-ht3, 5-ht4, 5-ht5a, 5-ht6 and 5-ht7a in avian germ cells and early embryos. |
2016-03-15 |
2023-08-12 |
Not clear |
| Franco Lapi, Laurent Azoulay, Abbas Kezouh, Jacques Benisty, Ilan Matok, Alessandro Mugelli, Samy Suiss. The use of antidepressants and the risk of chronic atrial fibrillation. Journal of clinical pharmacology. vol 55. issue 4. 2016-03-14. PMID:25427727. |
serotonin stimulation of the 5ht4 receptor might be responsible for an increased risk of atrial fibrillation (af). |
2016-03-14 |
2023-08-13 |
Not clear |
| C J G Delesalle, C Callens, I Van Colen, R A Lefebvr. Clinical Research Abstracts of the British Equine Veterinary Association Congress 2015. Equine veterinary journal. vol 47 Suppl 48. 2016-03-01. PMID:26376095. |
none of the 4 in vitro studies on 5-ht in horses provided evidence for neuronal 5-ht4 receptors, but none used the protocol as described in human studies [1-4]. |
2016-03-01 |
2023-08-13 |
human |
| H Lefebvre, C Duparc, G Prévost, M C Zennaro, J Bertherat, E Louise. Paracrine control of steroidogenesis by serotonin in adrenocortical neoplasms. Molecular and cellular endocrinology. vol 408. 2016-02-08. PMID:25433205. |
in the human adrenal gland, 5-ht, released by subcapsular mast cells, stimulates corticosteroid production through a paracrine mode of communication which involves 5-ht receptor type 4 (5-ht4) primarily located in zona glomerulosa. |
2016-02-08 |
2023-08-13 |
human |
| H Lefebvre, C Duparc, G Prévost, M C Zennaro, J Bertherat, E Louise. Paracrine control of steroidogenesis by serotonin in adrenocortical neoplasms. Molecular and cellular endocrinology. vol 408. 2016-02-08. PMID:25433205. |
as a result, 5-ht is much more efficient to stimulate aldosterone secretion than cortisol release in vitro and administration of 5-ht4 receptor agonists to healthy individuals is followed by an increase in plasma aldosterone levels without any change in plasma cortisol concentrations. |
2016-02-08 |
2023-08-13 |
human |
| Francesc Artiga. Developments in the field of antidepressants, where do we go now? European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 5. 2016-01-13. PMID:23706576. |
this will lead to the synthesis of new agents blocking the serotonin (and possibly norepinephrine) transporter which will also activate or block 5-ht receptors playing respectively positive (e.g., postsynaptic 5-ht1a, 5-ht4) or negative (e.g., presynaptic 5-ht1a,/1b, 5-ht2a, 5-ht2c,5-ht3, etc.) |
2016-01-13 |
2023-08-12 |
Not clear |
| Jaime Belkind-Gerson, Ryo Hotta, Nandor Nagy, Alyssa R Thomas, Hannah Graham, Lily Cheng, Juan Solorzano, Deanna Nguyen, Michal Kamionek, Jorg Dietrich, Bobby J Cherayil, Allan M Goldstei. Colitis induces enteric neurogenesis through a 5-HT4-dependent mechanism. Inflammatory bowel diseases. vol 21. issue 4. 2015-12-22. PMID:25742399. |
based on the evidence for the neurogenic role of serotonin (5-ht) in the postnatal gut and the observation of enteric neuronal hyperplasia in inflammatory bowel disease, we hypothesized that colitis induces a neurogenic response through 5-ht4 receptor signaling. |
2015-12-22 |
2023-08-13 |
Not clear |
| Katarzyna Panczyk, Sylwia Golda, Anna Waszkielewicz, Dorota Zelaszczyk, Agnieszka Gunia-Krzyzak, Henryk Maron. Serotonergic system and its role in epilepsy and neuropathic pain treatment: a review based on receptor ligands. Current pharmaceutical design. vol 21. issue 13. 2015-11-23. PMID:25412650. |
so far, participation in the epileptogenesis and maintenance of epilepsy was proved for 5-ht1a, 5-ht2c, 5-ht3, 5-ht4 and 5-ht7 receptors as well as 5-htt serotonin transporter. |
2015-11-23 |
2023-08-13 |
Not clear |
| Katarzyna Panczyk, Sylwia Golda, Anna Waszkielewicz, Dorota Zelaszczyk, Agnieszka Gunia-Krzyzak, Henryk Maron. Serotonergic system and its role in epilepsy and neuropathic pain treatment: a review based on receptor ligands. Current pharmaceutical design. vol 21. issue 13. 2015-11-23. PMID:25412650. |
according to the available data, neuropathic pain mechanisms involve 5-ht1a/1b/1d, 5-ht2a/2b/2c, 5-ht3, 5-ht4, 5-ht6, 5-ht7 receptors and 5-htt serotonin transporter. |
2015-11-23 |
2023-08-13 |
Not clear |