| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joanna Karbowska, Zdzisław Kocha. [Leptin as a mediator between obesity and cardiac dysfunction]. Postepy higieny i medycyny doswiadczalnej (Online). vol 66. 2013-05-02. PMID:22706112. |
moreover, leptin directly induced hypertrophy and hyperplasia in human and rodent cardiomyocytes, accompanied by cardiac extracellular matrix remodelling. |
2013-05-02 |
2023-08-12 |
human |
| Kavithalakshmi Sataranatarajan, Denis Feliers, Meenalakshmi M Mariappan, Hak Joo Lee, Myung Ja Lee, Robert T Day, Hima Bindu Yalamanchili, Goutam G Choudhury, Jeffrey L Barnes, Holly Van Remmen, Arlan Richardson, Balakuntalam S Kasinat. Molecular events in matrix protein metabolism in the aging kidney. Aging cell. vol 11. issue 6. 2013-04-18. PMID:23020145. |
renal hypertrophy was evident in middle-aged and old mice and was associated with glomerulomegaly and increase in mesangial fraction occupied by extracellular matrix. |
2013-04-18 |
2023-08-12 |
mouse |
| Liming Bian, Chieh Hou, Elena Tous, Reena Rai, Robert L Mauck, Jason A Burdic. The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy. Biomaterials. vol 34. issue 2. 2013-04-15. PMID:23084553. |
increased crosslinking also promoted hypertrophic differentiation of the chondrogenically induced mscs, resulting in more matrix calcification in vitro. |
2013-04-15 |
2023-08-12 |
mouse |
| Liming Bian, Chieh Hou, Elena Tous, Reena Rai, Robert L Mauck, Jason A Burdic. The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy. Biomaterials. vol 34. issue 2. 2013-04-15. PMID:23084553. |
supplementation with inhibitors of the small gtpase pathway involved in cytoskeletal tension or myosin ii had no effect on hypertrophic differentiation and matrix calcification, indicating that the differential response is unlikely to be related to force-sensing mechanotransduction mechanisms. |
2013-04-15 |
2023-08-12 |
mouse |
| Dao-quan Tang, Ya-qin Wei, Xiao-xing Yin, Qian Lu, Hui-hui Hao, Yun-peng Zhai, Jian-yun Wang, Jin Re. In vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose. Fitoterapia. vol 82. issue 6. 2013-04-08. PMID:21605637. |
in vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose. |
2013-04-08 |
2023-08-12 |
rat |
| Inês Falcão-Pires, Adelino F Leite-Moreir. Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment. Heart failure reviews. vol 17. issue 3. 2013-04-05. PMID:21626163. |
left ventricular hypertrophy, metabolic abnormalities, extracellular matrix changes, small vessel disease, cardiac autonomic neuropathy, insulin resistance, oxidative stress, and apoptosis are the most important contributors to diabetic cardiomyopathy onset and progression. |
2013-04-05 |
2023-08-12 |
human |
| Erdogan Kocamaz, Duygu Gok, Ayse Cetinkaya, A Cevik Tufa. Implication of C-type natriuretic peptide-3 signaling in glycosaminoglycan synthesis and chondrocyte hypertrophy during TGF-β1 induced chondrogenic differentiation of chicken bone marrow-derived mesenchymal stem cells. Journal of molecular histology. vol 43. issue 5. 2013-04-03. PMID:22714108. |
in conclusion, cnp-3/npr-b signaling may strongly be involved in synthesis of glycosaminoglycans of the chondrogenic matrix and hypertrophy of differentiated chondrocytes during tgf-β1 induced chondrogenic differentiation of mscs. |
2013-04-03 |
2023-08-12 |
human |
| Elen Rizzi, Carla S Ceron, Danielle A Guimaraes, Cibele M Prado, Marcos A Rossi, Raquel F Gerlach, Jose E Tanus-Santo. Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-β in renovascular hypertension-induced cardiac hypertrophy. Experimental and molecular pathology. vol 94. issue 1. 2013-04-03. PMID:23073243. |
temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and tgf-β in renovascular hypertension-induced cardiac hypertrophy. |
2013-04-03 |
2023-08-12 |
rat |
| Ivan Grskovic, Anna Kutsch, Christian Frie, Gergely Groma, Jacek Stermann, Ursula Schlötzer-Schrehardt, Anja Niehoff, Stephen E Moss, Sabrina Rosenbaum, Ernst Pöschl, Markus Chmielewski, Gunter Rappl, Hinrich Abken, John F Bateman, Kathryn Se Cheah, Mats Paulsson, Bent Brachvoge. Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 27. issue 11. 2013-03-26. PMID:22692895. |
by binding to the extracellular matrix protein collagen x and matrix vesicles, annexins were proposed to anchor matrix vesicles in the extracellular space of hypertrophic chondrocytes to initiate the calcification of cartilage. |
2013-03-26 |
2023-08-12 |
mouse |
| V Catalán, J Gómez-Ambrosi, A Rodríguez, G Frühbec. Role of extracellular matrix remodelling in adipose tissue pathophysiology: relevance in the development of obesity. Histology and histopathology. vol 27. issue 12. 2013-03-21. PMID:23059882. |
adipose tissue responds dynamically to alterations in nutrient excess through adipocyte hypertrophy and hyperplasia, followed by increased angiogenesis, immune cell infiltration, extracellular matrix (ecm) overproduction, and thus, increased production of proinflammatory adipokines during the progression of chronic inflammation. |
2013-03-21 |
2023-08-12 |
human |
| Nikhil C Adi, Jennipher N Adi, Liliana Cesar, Arthur S Agatston, Paul Kurlansky, Keith A Webste. Influence of diet on visceral adipose remodeling in NONcNZO10 mice with polygenic susceptibility for type 2 diabetes. Obesity (Silver Spring, Md.). vol 20. issue 10. 2013-03-19. PMID:22858798. |
expansion of vat involves adipocyte hyperplasia and hypertrophy and requires breakdown of the extracellular matrix and increased vascular outgrowth. |
2013-03-19 |
2023-08-12 |
mouse |
| Giuseppe Distefano, Pietro Sciacc. Molecular pathogenesis of myocardial remodeling and new potential therapeutic targets in chronic heart failure. Italian journal of pediatrics. vol 38. 2013-03-12. PMID:22971785. |
typical features of myocardial remodeling are represented by cardiomyocytes hypertrophy and apoptosis, extracellular matrix alterations, mesenchymal fibrotic and phlogistic processes and by cardiac gene expression modifications with fetal genetic program reactivation. |
2013-03-12 |
2023-08-12 |
Not clear |
| Leonarda J van den Broek, Frank B Niessen, Rik J Scheper, Susan Gibb. Development, validation and testing of a human tissue engineered hypertrophic scar model. ALTEX. vol 29. issue 4. 2013-03-12. PMID:23138509. |
here we describe the development and validation of a tissue-engineered human hypertrophic scar (htscar) model based on reconstructed epidermis on a dermal matrix containing adipose derived mesenchymal stem cells (asc). |
2013-03-12 |
2023-08-12 |
human |
| Sundaravadivel Balasubramanian, Lakeya Quinones, Harinath Kasiganesan, Yuhua Zhang, Dorea L Pleasant, Kamala P Sundararaj, Michael R Zile, Amy D Bradshaw, Dhandapani Kuppuswam. β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse. PloS one. vol 7. issue 9. 2013-03-05. PMID:22984613. |
β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse. |
2013-03-05 |
2023-08-12 |
mouse |
| Roger M Maso. Fell-Muir lecture: Connective tissue growth factor (CCN2) -- a pernicious and pleiotropic player in the development of kidney fibrosis. International journal of experimental pathology. vol 94. issue 1. 2013-03-05. PMID:23110747. |
connective tissue growth factor stimulates the development of fibrosis in the kidney in many ways including activating cells to increase extracellular matrix synthesis, inducing cell cycle arrest and hypertrophy, and prolonging survival of activated cells. |
2013-03-05 |
2023-08-12 |
human |
| Richard D Bagnall, Tatiana Tsoutsman, Rhian E Shephard, William Ritchie, Christopher Semsaria. Global microRNA profiling of the mouse ventricles during development of severe hypertrophic cardiomyopathy and heart failure. PloS one. vol 7. issue 9. 2013-02-15. PMID:23024758. |
time-course analysis revealed that decreased expression of mir-1 and mir-133a commences at a pre-disease stage, and precedes upregulation of target genes causal of cardiac hypertrophy and extracellular matrix remodelling, suggesting a role for mir-1 and mir-133a in early disease development. |
2013-02-15 |
2023-08-12 |
mouse |
| Anne M Fitzpatrick, Dean P Jones, Lou Ann S Brow. Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities. Antioxidants & redox signaling. vol 17. issue 2. 2013-02-11. PMID:22304503. |
whereas inflammation is important for tissue regeneration and wound healing, the profound and sustained inflammatory response associated with asthma may result in airway remodeling that involves smooth muscle hypertrophy, epithelial goblet-cell hyperplasia, and permanent deposition of airway extracellular matrix proteins. |
2013-02-11 |
2023-08-12 |
human |
| Xun Tan, Juan Chai, Shi-Cheng Bi, Jun-Jun Li, Wen-Wen Li, Ji-Yong Zho. Involvement of matrix metalloproteinase-2 in medial hypertrophy of pulmonary arterioles in broiler chickens with pulmonary arterial hypertension. Veterinary journal (London, England : 1997). vol 193. issue 2. 2013-02-08. PMID:22377328. |
involvement of matrix metalloproteinase-2 in medial hypertrophy of pulmonary arterioles in broiler chickens with pulmonary arterial hypertension. |
2013-02-08 |
2023-08-12 |
Not clear |
| Frank Thiele, Christian M Cohrs, Armando Flor, Thomas S Lisse, Gerhard K H Przemeck, Marion Horsch, Anja Schrewe, Valerie Gailus-Durner, Boris Ivandic, Hugo A Katus, Wolfgang Wurst, Catherine Reisenberg, Hollis Chaney, Helmut Fuchs, Wolfgang Hans, Johannes Beckers, Joan C Marini, Martin Hrabé de Angeli. Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms. Human molecular genetics. vol 21. issue 16. 2013-02-06. PMID:22589248. |
in addition, dysregulated gene expression of nppa, different types of collagen and agt in heart and lung tissue support a bone-independent vicious cycle of heart dysfunction, including hypertrophy, loss of myocardial matrix integrity, pulmonary hypertension, pneumonia and hypoxia leading to death in aga2. |
2013-02-06 |
2023-08-12 |
mouse |
| Shaojiang Tian, Junming Tang, Huihui Liu, Liping Wang, Jianming Shen, Junfeng Li, Yanjie Ga. Propyl gallate plays a nephroprotective role in early stage of diabetic nephropathy associated with suppression of glomerular endothelial cell proliferation and angiogenesis. Experimental diabetes research. vol 2012. 2013-01-30. PMID:22988451. |
we found that glomerular hypertrophy, glomerular mesangial matrix expansion, and albuminuria were significantly increased in dn rats. |
2013-01-30 |
2023-08-12 |
rat |