| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tatiana Anan'ina, Alena Kisel, Marina Kudabaeva, Galina Chernysheva, Vera Smolyakova, Konstantin Usov, Elena Krutenkova, Mark Plotnikov, Marina Khodanovic. Neurodegeneration, Myelin Loss and Glial Response in the Three-Vessel Global Ischemia Model in Rat. International journal of molecular sciences. vol 21. issue 17. 2021-02-24. PMID:32872364. |
in addition, we investigated the relationships between demyelination and changes in microglia and astrocytes, as well as oligodendrogenesis in the hippocampus; (2) methods: adult male wistar rats ( |
2021-02-24 |
2023-08-13 |
human |
| Xiali Zhong, Jingwei Wu, Weijian Ke, Yuejin Yu, Di Ji, Jianmeng Kang, Jiahuang Qiu, Can Wang, Panpan Yu, Yanhong We. Neonatal exposure to organophosphorus flame retardant TDCPP elicits neurotoxicity in mouse hippocampus via microglia-mediated inflammation in vivo and in vitro. Archives of toxicology. vol 94. issue 2. 2021-02-23. PMID:31894355. |
the mrna levels of pro-inflammatory factors il-1β, tnfα and ccl2 dose dependently increased in the hippocampus at both 24 h and 28 days following exposure, accompanied by microglia activation characterized by an amoeboid-like phenotype. |
2021-02-23 |
2023-08-13 |
mouse |
| Xiali Zhong, Jingwei Wu, Weijian Ke, Yuejin Yu, Di Ji, Jianmeng Kang, Jiahuang Qiu, Can Wang, Panpan Yu, Yanhong We. Neonatal exposure to organophosphorus flame retardant TDCPP elicits neurotoxicity in mouse hippocampus via microglia-mediated inflammation in vivo and in vitro. Archives of toxicology. vol 94. issue 2. 2021-02-23. PMID:31894355. |
neurite outgrowth of primary mouse hippocampal neurons was inhibited by treatment with the conditioned medium harvested from microglia exposed to tdcpp. |
2021-02-23 |
2023-08-13 |
mouse |
| S Alboni, C Benatti, C Colliva, G Radighieri, J M C Blom, N Brunello, F Tascedd. Vortioxetine Prevents Lipopolysaccharide-Induced Memory Impairment Without Inhibiting the Initial Inflammatory Cascade. Frontiers in pharmacology. vol 11. 2021-02-23. PMID:33613281. |
moreover, the expressions of markers of immune activation and m1/m2 markers of microglia polarization were measured in the dorsal and ventral parts of the hippocampus. |
2021-02-23 |
2023-08-13 |
mouse |
| S Alboni, C Benatti, C Colliva, G Radighieri, J M C Blom, N Brunello, F Tascedd. Vortioxetine Prevents Lipopolysaccharide-Induced Memory Impairment Without Inhibiting the Initial Inflammatory Cascade. Frontiers in pharmacology. vol 11. 2021-02-23. PMID:33613281. |
these results demonstrate that a chronic administration of vortioxetine specifically prevents lps-induced memory impairment, without affecting acute sickness behavior and anhedonia, and suggest that hippocampal microglia may represent a cellular target of this novel antidepressant medication. |
2021-02-23 |
2023-08-13 |
mouse |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
microglia and astrocytes in spinal dorsal horn (sdh), prefrontal cortex (pfc), anterior cingulate cortex (acc), and hippocampus were analyzed. |
2021-02-20 |
2023-08-13 |
rat |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
in addition, it reduced the activation of astrocyte but not microglia in pfc, acc, and hippocampus. |
2021-02-20 |
2023-08-13 |
rat |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
intravenous lidocaine may relieve phn by inhibiting the activation of microglia and astrocyte in sdh or by reducing the neuroinflammation and astrocyte activation in pfc, acc, and hippocampus. |
2021-02-20 |
2023-08-13 |
rat |
| Shouhong Zhou, Shanshan Chen, Wenxia Xie, Xiaoxiao Guo, Jianfeng Zha. Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats. Neuropeptides. vol 81. 2021-02-12. PMID:31932110. |
microglia polarization of hippocampus is involved in the mechanism of apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats. |
2021-02-12 |
2023-08-13 |
rat |
| Shouhong Zhou, Shanshan Chen, Wenxia Xie, Xiaoxiao Guo, Jianfeng Zha. Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats. Neuropeptides. vol 81. 2021-02-12. PMID:31932110. |
chronic stress induces the activation of hippocampal microglia, which produces many inflammatory mediators and mediates the occurrence of depression. |
2021-02-12 |
2023-08-13 |
rat |
| Shouhong Zhou, Shanshan Chen, Wenxia Xie, Xiaoxiao Guo, Jianfeng Zha. Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats. Neuropeptides. vol 81. 2021-02-12. PMID:31932110. |
double-labelling immunofluorescence co-localization showed that, compared with the cwirs + saline group, cwirs + apelin-13 group significantly inhibited the co-localization expression of iba-1 and inos, and promoted the co-localization expression of iba-1 and arg1 in hippocampus microglia. |
2021-02-12 |
2023-08-13 |
rat |
| Yue Qu, Jun-Yan Wu, Qing Yua. [Effect of acupuncture on hippocampal inflammation in rats with intrauterine distress induced hypoxic-ischemic brain injury]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 1. 2021-02-10. PMID:33559420. |
to observe the effects of acupuncture on the behavior, serum inflammatory cytokines, hippocampal nod-like receptor protein 3(nlrp3) inflammasome-related proteins and microglia activation in rats with intrauterine distress induced ischemia-hypoxic brain injury (hibd), so as to explore the mechanism of acupuncture underlying treatment of hibd by regulating hippocampal inflammation. |
2021-02-10 |
2023-08-13 |
rat |
| Tian Lin, Juan Du, Li Liu, Zheng Wu, Xiangkai Kong, Yu Liu, Yiling Ca. Treatment with Minocycline Suppresses Microglia Activation and Reverses Neural Stem Cells Loss after Simulated Microgravity. BioMed research international. vol 2020. 2021-02-09. PMID:32382569. |
the present study aimed to investigate the effect of microglia on simulated microgravity-induced hippocampal neurogenesis reduction and the possible mechanism underlying. |
2021-02-09 |
2023-08-13 |
rat |
| Tian Lin, Juan Du, Li Liu, Zheng Wu, Xiangkai Kong, Yu Liu, Yiling Ca. Treatment with Minocycline Suppresses Microglia Activation and Reverses Neural Stem Cells Loss after Simulated Microgravity. BioMed research international. vol 2020. 2021-02-09. PMID:32382569. |
additionally, liquid protein chip analysis was applied to detect proinflammatory factors in hippocampus in order to find out the cytokines responsible for microglia activation after microgravity. |
2021-02-09 |
2023-08-13 |
rat |
| Jing-Jing Du, Zhi-Qin Liu, Yue Yan, Jing Xiong, Xiao-Tao Jia, Zheng-Li Di, Jing-Jing Re. The Cannabinoid WIN 55,212-2 Reduces Delayed Neurologic Sequelae After Carbon Monoxide Poisoning by Promoting Microglial M2 Polarization Through ST2 Signaling. Journal of molecular neuroscience : MN. vol 70. issue 3. 2021-02-08. PMID:31732924. |
this behavioral improvement was accompanied by reduced neuron loss, decreased production of pro-inflammatory cytokines, and a limited number of microglia in the hippocampus. |
2021-02-08 |
2023-08-13 |
rat |
| Jing-Jing Du, Zhi-Qin Liu, Yue Yan, Jing Xiong, Xiao-Tao Jia, Zheng-Li Di, Jing-Jing Re. The Cannabinoid WIN 55,212-2 Reduces Delayed Neurologic Sequelae After Carbon Monoxide Poisoning by Promoting Microglial M2 Polarization Through ST2 Signaling. Journal of molecular neuroscience : MN. vol 70. issue 3. 2021-02-08. PMID:31732924. |
moreover, win 55,212-2 elevated the protein expression of il-33 (the ligand of st2) and st2, increased the ratio of cd206-positive (m2 phenotype) and st2-positive microglia, and augmented production of m2 microglia-associated cytokines in the hippocampus of co-exposed rats. |
2021-02-08 |
2023-08-13 |
rat |
| Yuchen Song, Haixia Yuan, Tianyi Chen, Manqi Lu, Shuang Lei, Xinmin Ha. An Shen Ding Zhi Ling Alleviates Symptoms of Attention Deficit Hyperactivity Disorder via Anti-Inflammatory Effects in Spontaneous Hypertensive Rats. Frontiers in pharmacology. vol 11. 2021-02-06. PMID:33536923. |
asdzl reduced the pro-inflammatory factors interleukin (il)-1β, il-4, il-6, tumor necrosis factor (tnf)-α and monocyte chemoattractant protein (mcp)-1 and increased anti-inflammatory factor il-10 in shrs, and decreased the activation of microglia, astrocytes and mast cells in the prefrontal cortex (pfc) and hippocampus. |
2021-02-06 |
2023-08-13 |
rat |
| Yu Takahashi, Hideaki Wakita, Kenmei Mizutani, Atsushi Watanabe, Shigeru Sonoda, Hidekazu Tomimot. Selective accumulation of adiponectin in the cerebral cortex under chronic cerebral hypoperfusion in the rat. Neuroreport. vol 31. issue 2. 2021-02-03. PMID:31855901. |
microglia are activated shortly after ischemia and correlate with the severity of white matter and hippocampal tissue damage. |
2021-02-03 |
2023-08-13 |
rat |
| Chuan He, Zhong-Sheng Huang, Hong-Ru Chen, Chao-Chao Yu, Xue-Song Wang, Tao Jiang, Li-Hong Kon. [Effect of pretreatment of acupuncture on learning-memory ability and related protein of NLRP3 inflammasome in hippocampus in Alzheimer's disease like rats]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 40. issue 12. 2021-02-01. PMID:33415876. |
to observe the effect of pretreatment of acupuncture on the expression of nucleotide-binding oligomerization domain-like receptor 3(nlrp3), caspase-1, interleukin1β(il-1β) and the number of activated microglia (mg) in the hippocampus in alzheimer's disease (ad) like rats, so as to explore the mechanism of pretreatment of acupuncture in preventing and treating ad. |
2021-02-01 |
2023-08-13 |
rat |
| Katherine R Giordano, Charlotte R Denman, Phoebe S Dubisch, Murtaza Akhter, Jonathan Lifshit. An update on the rod microglia variant in experimental and clinical brain injury and disease. Brain communications. vol 3. issue 1. 2021-01-30. PMID:33501429. |
rod microglia are most commonly observed in the cortex, aligned perpendicular to the dural surface and adjacent to neuronal processes; in the hippocampus, they are aligned perpendicular to hippocampal layers. |
2021-01-30 |
2023-08-13 |
Not clear |