| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Martí-Clú. Natural apoptosis in developing mice dopamine midbrain neurons and vermal Purkinje cells. Folia neuropathologica. vol 54. issue 2. 2017-04-13. PMID:27543775. |
natural apoptosis in developing mice dopamine midbrain neurons and vermal purkinje cells. |
2017-04-13 |
2023-08-13 |
mouse |
| Enkhjargal Bayarsaikhan, Delger Bayarsaikhan, Jaesuk Lee, Myeongjoo Son, Seyeon Oh, Jeongsik Moon, Hye-Jeong Park, Arivazhagan Roshini, Seung U Kim, Byoung-Joon Song, Seung-Mook Jo, Kyunghee Byun, Bonghee Le. Microglial AGE-albumin is critical for neuronal death in Parkinson's disease: a possible implication for theranostics. International journal of nanomedicine. vol 10 Spec Iss. 2017-04-04. PMID:27601894. |
accumulated age-albumin upregulates the receptor to age, leading to apoptosis of human primary dopamine (da) neurons. |
2017-04-04 |
2023-08-13 |
human |
| Xiaolie He, Yanjing Zhu, Mei Wang, Guoxin Jing, Rongrong Zhu, Shilong Wan. Antidepressant effects of curcumin and HU-211 coencapsulated solid lipid nanoparticles against corticosterone-induced cellular and animal models of major depression. International journal of nanomedicine. vol 11. 2017-02-13. PMID:27757031. |
cur/slns-hu-211 can effectively protect pc12 cells from corticosterone-induced apoptosis and can release more dopamine, which may be associated with the higher uptake of cur/slns-hu-211 shown by cellular uptake behavior analysis. |
2017-02-13 |
2023-08-13 |
mouse |
| Naishun Liao, Ming Wu, Fan Pan, Jiumao Lin, Zuanfang Li, Da Zhang, Yingchao Wang, Youshi Zheng, Jun Peng, Xiaolong Liu, Jingfeng Li. Poly (dopamine) coated superparamagnetic iron oxide nanocluster for noninvasive labeling, tracking, and targeted delivery of adipose tissue-derived stem cells. Scientific reports. vol 6. 2016-12-13. PMID:26728448. |
herein, the adipose tissue-derived stem cells (adscs) were efficiently labeled with spions coated with poly (dopamine) (spions cluster@pda), without affecting their viability, proliferation, apoptosis, surface marker expression, as well as their self-renew ability and multi-differentiation potential. |
2016-12-13 |
2023-08-13 |
mouse |
| Nilesh Sudhakar Ambhore, Karthik Yamjala, Shubhashri Mohire, Kalidhindi Rama Satyanarayana Raju, Shashank Mulukutla, Vishakantha Murthy, Mahesh Tondhawada, Kannan Elang. Pharmacokinetic and tissue distribution studies of 1,9-pyrazoloanthrone, a c-Jun-N-terminal kinase inhibitor in Wistar rats by a simple and sensitive HPLC method. Journal of pharmaceutical and biomedical analysis. vol 120. 2016-10-24. PMID:26704630. |
jnk pathway activates c-jun(s) which are responsible for cell apoptosis; as a result, inhibitors of jnk pathway have the potential to prevent dopaminergic neurons from death and decrease the loss of dopamine in substantia nigra pars compacta (snpc). |
2016-10-24 |
2023-08-13 |
rat |
| N Brew, A Azhan, I den Heijer, M Boomgardt, G I Davies, I Nitsos, S L Miller, A M Walker, D W Walker, F Y Won. Dopamine treatment during acute hypoxia is neuroprotective in the developing sheep brain. Neuroscience. vol 316. 2016-10-18. PMID:26711678. |
we conclude that pretreatment with dopamine does not exacerbate hypoxia-induced injury in the immature brain and may be neuroprotective because it led to decreased apoptosis, oxidative stress and neuroinflammation in the cerebral white matter and decreased neuroinflammation in the caudate nucleus. |
2016-10-18 |
2023-08-13 |
Not clear |
| George J Dugbartey, Fatemeh Talaei, Martin C Houwertjes, Maaike Goris, Anne H Epema, Hjalmar R Bouma, Robert H Hennin. Dopamine treatment attenuates acute kidney injury in a rat model of deep hypothermia and rewarming - The role of renal H2S-producing enzymes. European journal of pharmacology. vol 769. 2016-09-21. PMID:26593431. |
we previously found that dopamine prevents hypothermia and rewarming-induced apoptosis in cultured cells through increased expression of the h2s-producing enzyme cystathionine β-synthase (cbs). |
2016-09-21 |
2023-08-13 |
rat |
| Mona A El-Ghazaly, Nermin A H Sadik, Engy R Rashed, Amal A Abd-El-Fatta. Neuroprotective effect of EGb761® and low-dose whole-body γ-irradiation in a rat model of Parkinson's disease. Toxicology and industrial health. vol 31. issue 12. 2016-09-16. PMID:23696346. |
reserpine injection resulted in the depletion of striatal dopamine (da) level, increased catalepsy score, increased oxidative stress indicated via depletion of glutathione (gsh), increased malondialdehyde (mda) and iron levels, decreased da metabolites metabolizing enzymes; indicated by inhibition by glutathione-s-transferase, and nicotinamide adenine dinucleotide phosphate (nadph)-quinone oxidoreductase (nqo) activities, mitochondrial dysfunction; indicated by declined complex i activity, and adenosine triphosphate (atp) level and increased apoptosis; indicated by decreased mitochondrial b cell lymphoma-2 (bcl-2) protein level and by transmission electron microscope. |
2016-09-16 |
2023-08-12 |
rat |
| Yashasvi Matam, Bruce D Ray, Horia I Petrach. Direct affinity of dopamine to lipid membranes investigated by Nuclear Magnetic Resonance spectroscopy. Neuroscience letters. vol 618. 2016-08-22. PMID:26960008. |
this result suggests that dopamine's interaction with lipid membranes is complex and involves both binding as well as permeation through lipid bilayers, a combination that could be an effective trigger for apoptosis of dopamine-generating cells. |
2016-08-22 |
2023-08-13 |
Not clear |
| Lei Sheng, Ling Wang, Mingyu Su, Xiaoyang Zhao, Renping Hu, Xiaohong Yu, Jie Hong, Dong Liu, Bingqing Xu, Yunting Zhu, Han Wang, Fashui Hon. Mechanism of TiO2 nanoparticle-induced neurotoxicity in zebrafish (Danio rerio). Environmental toxicology. vol 31. issue 2. 2016-08-15. PMID:25059219. |
our data indicated that spatial recognition memory and levels of norepinephrine, dopamine, and 5-hydroxytryptamine were significantly decreased and no levels were markedly elevated, and over proliferation of glial cells, neuron apoptosis, and tio2 np aggregation were observed after low dose exposures of tio2 nps. |
2016-08-15 |
2023-08-13 |
zebrafish |
| Musa V Mabandla, Mpumelelo Nyoka, Willie M U Daniel. Early use of oleanolic acid provides protection against 6-hydroxydopamine induced dopamine neurodegeneration. Brain research. vol 1622. 2016-06-02. PMID:26111646. |
neurochemical changes were assessed using a dopamine elisa kit and mitochondrial apoptosis was measured using a mitochondrial apoptosis detection kit. |
2016-06-02 |
2023-08-13 |
rat |
| Wei Scarano, Hongxu Lu, Martina H Stenze. Boronic acid ester with dopamine as a tool for bioconjugation and for visualization of cell apoptosis. Chemical communications (Cambridge, England). vol 50. issue 48. 2016-04-25. PMID:24812657. |
boronic acid ester with dopamine as a tool for bioconjugation and for visualization of cell apoptosis. |
2016-04-25 |
2023-08-13 |
Not clear |
| Deepmala, John Slattery, Nihit Kumar, Leanna Delhey, Michael Berk, Olivia Dean, Charles Spielholz, Richard Fry. Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review. Neuroscience and biobehavioral reviews. vol 55. 2016-04-04. PMID:25957927. |
over the past decade, there has been growing evidence for the use of nac in treating psychiatric and neurological disorders, considering its role in attenuating pathophysiological processes associated with these disorders, including oxidative stress, apoptosis, mitochondrial dysfunction, neuroinflammation and glutamate and dopamine dysregulation. |
2016-04-04 |
2023-08-13 |
Not clear |
| Mojtaba Golpich, Elham Amini, Fatemeh Hemmati, Norlinah Mohamed Ibrahim, Behrouz Rahmani, Zahurin Mohamed, Azman Ali Raymond, Leila Dargahi, Rasoul Ghasemi, Abolhassan Ahmadian. Glycogen synthase kinase-3 beta (GSK-3β) signaling: Implications for Parkinson's disease. Pharmacological research. vol 97. 2016-03-01. PMID:25829335. |
parkinson's disease (pd) is a chronic neurodegenerative movement disorder characterized by the progressive and massive loss of dopaminergic neurons by neuronal apoptosis in the substantia nigra pars compacta and depletion of dopamine in the striatum, which lead to pathological and clinical abnormalities. |
2016-03-01 |
2023-08-13 |
Not clear |
| Beatrice Macchi, Rosanna Di Paola, Francesca Marino-Merlo, Maria Rosa Felice, Salvatore Cuzzocrea, Antonio Mastin. Inflammatory and cell death pathways in brain and peripheral blood in Parkinson's disease. CNS & neurological disorders drug targets. vol 14. issue 3. 2016-02-01. PMID:25714978. |
the release of these inflammatory mediators in addition to deprivation in growth factors and increase of calcium and dopamine seem implicated in triggering apoptosis. |
2016-02-01 |
2023-08-13 |
Not clear |
| Maria Jose Garcia Barrado, Maria Carmen Iglesias Osma, Enrique J Blanco, Marta Carretero Hernández, Virginia Sánchez Robledo, Leonardo Catalano Iniesta, Sixto Carrero, Jose Carreter. Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells. PloS one. vol 10. issue 4. 2016-01-18. PMID:25886074. |
the aim of the present study is to analyze whether dopamine is a regulator of the proliferation and apoptosis of rat pancreatic beta cells after glucose-stimulated insulin secretion. |
2016-01-18 |
2023-08-13 |
rat |
| Maria Jose Garcia Barrado, Maria Carmen Iglesias Osma, Enrique J Blanco, Marta Carretero Hernández, Virginia Sánchez Robledo, Leonardo Catalano Iniesta, Sixto Carrero, Jose Carreter. Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells. PloS one. vol 10. issue 4. 2016-01-18. PMID:25886074. |
apoptosis in pancreatic islets and beta cells was increased by treatment with 1 and 10 μm dopamine along 12 h. in conclusion, these results suggest that dopamine could modulate the proliferation and apoptosis of pancreatic beta cells and that dopamine may be involved in the maintenance of pancreatic islets. |
2016-01-18 |
2023-08-13 |
rat |
| Jiaojiao Qin, Meilong Wu, Shu Yu, Xiaorong Gao, Jingjing Zhang, Xingyue Dong, Jinyan Ji, Yuxi Zhang, Lin Zhou, Qi Zhang, Fei Din. Pyrroloquinoline quinone-conferred neuroprotection in rotenone models of Parkinson's disease. Toxicology letters. vol 238. issue 3. 2015-12-30. PMID:26276080. |
pre-treatment with pqq prevented cultured sh-sy5y cells from rotenone-induced apoptosis, accompanied by modulation of apoptosis-related proteins (bcl-2, bax and smac), restoration of the mitochondrial membrane potential, inhibition of intracellular reactive oxygen species (ros) production, suppression of tyrosine residues nitration, and dopamine redistribution. |
2015-12-30 |
2023-08-13 |
rat |
| Xiang-Yun Li, Guang-Hai Mei, Qiang Dong, Yu Zhang, Zhuang-Li Guo, Jing-Jing Su, Yu-Ping Tang, Xue-Hong Jin, Hou-Guang Zhou, Yan-Yan Huan. Enhanced Neuroprotective Effects of Coadministration of Tetrandrine with Glutathione in Preclinical Model of Parkinson's Disease. Parkinson's disease. vol 2015. 2015-12-15. PMID:26664824. |
levels in the redox system, dopamine (da) metabolism, dopaminergic neuronal survival, and apoptosis of the substantia nigra (sn) and striatum, as well as the rotational behavior of animals were examined after a 50-day administration of gsh + tet (or gsh) and/or l-3,4-dihydroxyphenylalanine (l-dopa) to pd rats. |
2015-12-15 |
2023-08-13 |
rat |
| Muhammad Imran Naseer, Ikram Ullah, Mahmood Rasool, Shakeel Ahmed Ansari, Ishfaq Ahmed Sheikh, Fehmida Bibi, Adeel Gulzar Chaudhary, Mohammed H Al-Qahtani, Myeong Ok Ki. Downregulation of dopamine D₁ receptors and increased neuronal apoptosis upon ethanol and PTZ exposure in prenatal rat cortical and hippocampal neurons. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 35. issue 11. 2015-11-10. PMID:24810836. |
downregulation of dopamine d₁ receptors and increased neuronal apoptosis upon ethanol and ptz exposure in prenatal rat cortical and hippocampal neurons. |
2015-11-10 |
2023-08-13 |
rat |