| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Vergun, A I Sobolevsky, M V Yelshansky, J Keelan, B I Khodorov, M R Duche. Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture. The Journal of physiology. vol 531. issue Pt 1. 2001-05-10. PMID:11179399. |
exposure of hippocampal neurones to glutamate at toxic levels is associated with a profound collapse of mitochondrial potential and deregulation of calcium homeostasis. |
2001-05-10 |
2023-08-12 |
rat |
| J P Ren, H L Xia, J S Chen. [The relation between changes of nitric oxide synthase in hippocampus and activities of excitatory amino acid receptor during epilepsy]. Sheng li xue bao : [Acta physiologica Sinica]. vol 50. issue 4. 2001-05-10. PMID:11324544. |
the time course of alteration in neuronal nitric oxide synthase (nnos) and the influence of glutamate receptor antagonists on immunoreactivity of nnos were investigated immunohistochemically in rat hippocampus during penicillin-induced epilepsy. |
2001-05-10 |
2023-08-12 |
rat |
| L H Wang, P Zhao, Y L Huang, J S Chen. [Changes of intracellular calcium level in hippocampal slice neurons: a confocal laser scanning microscopic study]. Sheng li xue bao : [Acta physiologica Sinica]. vol 50. issue 3. 2001-05-10. PMID:11324580. |
with this improvement of labeling and the use of the confocal laser scanning microscope (leica lasetechnik gmbh), changes of calcium fluorescence intensity in ca1 pyramidal cells of rat hippocampal slices on the models of mimic epilepsy (induced by penicillin or glutamate) or hypoglycemia/hypoxia were studied in vitro. |
2001-05-10 |
2023-08-12 |
rat |
| S V Vellucci, R F Parrot. Hippocampal gene expression in the pig: upregulation of corticotrophin releasing hormone mRNA following central administration of the peptide. Neuropeptides. vol 34. issue 3-4. 2001-05-03. PMID:11021984. |
in this study, mrna for crh and selected ionotropic glutamate receptor (iglur) subunits (nr1, glur2, glur3) was quantified in the hippocampus of pigs in which stress was simulated by central administration of crh (100 microg). |
2001-05-03 |
2023-08-12 |
rat |
| J B McCarthy, S T Lim, N B Elkind, J S Trimmer, R M Duvoisin, E Rodriguez-Boulan, M J Capla. The C-terminal tail of the metabotropic glutamate receptor subtype 7 is necessary but not sufficient for cell surface delivery and polarized targeting in neurons and epithelia. The Journal of biological chemistry. vol 276. issue 12. 2001-05-03. PMID:11106656. |
here we report that metabotropic glutamate receptor subtype 7a (mglur7a) is polarized at the basolateral surface when expressed in madin-darby canine kidney (mdck) epithelial cells but is not polarized when expressed in cultured hippocampal neurons. |
2001-05-03 |
2023-08-12 |
human |
| H P Chang, Y L Ma, F J Wan, L Y Tsai, F P Lindberg, E H Le. Functional blocking of integrin-associated protein impairs memory retention and decreases glutamate release from the hippocampus. Neuroscience. vol 102. issue 2. 2001-05-03. PMID:11166115. |
functional blocking of integrin-associated protein impairs memory retention and decreases glutamate release from the hippocampus. |
2001-05-03 |
2023-08-12 |
mouse |
| H P Chang, Y L Ma, F J Wan, L Y Tsai, F P Lindberg, E H Le. Functional blocking of integrin-associated protein impairs memory retention and decreases glutamate release from the hippocampus. Neuroscience. vol 102. issue 2. 2001-05-03. PMID:11166115. |
at a dose that effectively impairs both memory retention and long-term potentiation, integrin-associated protein monoclonal antibody also significantly blocks potassium chloride-induced glutamate release from the hippocampus in vivo. |
2001-05-03 |
2023-08-12 |
mouse |
| H P Chang, Y L Ma, F J Wan, L Y Tsai, F P Lindberg, E H Le. Functional blocking of integrin-associated protein impairs memory retention and decreases glutamate release from the hippocampus. Neuroscience. vol 102. issue 2. 2001-05-03. PMID:11166115. |
from these results we suggest that integrin-associated protein monoclonal antibody may impair synaptic plasticity and behavioral plasticity in mice through blockade of granular cell attachment to extracellular matrix protein and the subsequent signal transduction, and through inhibition of glutamate release from the hippocampus. |
2001-05-03 |
2023-08-12 |
mouse |
| G Segovia, A Porras, A Del Arco, F Mor. Glutamatergic neurotransmission in aging: a critical perspective. Mechanisms of ageing and development. vol 122. issue 1. 2001-04-26. PMID:11163621. |
first, an age-related decrease of glutamate content in tissue from cerebral cortex and hippocampus has been reported, although it may be mainly a consequence of changes in metabolic activity rather than glutamatergic neurotransmission. |
2001-04-26 |
2023-08-12 |
rat |
| K Abe, N Matsuk. Measurement of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction activity and lactate dehydrogenase release using MTT. Neuroscience research. vol 38. issue 4. 2001-04-26. PMID:11164558. |
this method was successfully applied for evaluating t-butyl hydroperoxide toxicity in cultured rat cortical astrocytes and glutamate toxicity in cultured rat hippocampal neurons. |
2001-04-26 |
2023-08-12 |
rat |
| M C Walker, A Ruiz, D M Kullman. Monosynaptic GABAergic signaling from dentate to CA3 with a pharmacological and physiological profile typical of mossy fiber synapses. Neuron. vol 29. issue 3. 2001-04-26. PMID:11301029. |
mossy fibers are the sole excitatory projection from dentate gyrus granule cells to the hippocampus, where they release glutamate, dynorphin, and zinc. |
2001-04-26 |
2023-08-12 |
Not clear |
| D D Savage, R Galindo, S A Queen, L L Paxton, A M Alla. Characterization of electrically evoked [3H]-D-aspartate release from hippocampal slices. Neurochemistry international. vol 38. issue 3. 2001-04-19. PMID:11099785. |
we demonstrate here that [3h]-d-aspartate (d-asp) release can be detected from hippocampal slices at lower stimulation intensities in the presence of a glutamate reuptake inhibitor. |
2001-04-19 |
2023-08-12 |
Not clear |
| B Hassel, E Taubøll, L Gjersta. Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels. Epilepsy research. vol 43. issue 2. 2001-04-19. PMID:11164704. |
the hippocampal level of gaba increased 25%, and the activities of glutamate decarboxylase and succinic semialdehyde/gaba transaminase increased 12 and 21% (p< 0.05), respectively, indicating increased gaba turnover. |
2001-04-19 |
2023-08-12 |
rat |
| b' V Erakovi\\xc4\\x87, G Zupan, J Varljen, J Laginja, A Simoni\\xc4\\x8. Altered activities of rat brain metabolic enzymes caused by pentylenetetrazol kindling and pentylenetetrazol--induced seizures. Epilepsy research. vol 43. issue 2. 2001-04-19. PMID:11164705.' |
glutamate dehydrogenase, aspartate-aminotransferase (ast), alanine-aminotransferase, gamma-glutamyltransferase, alkaline phosphatase (alp), lactate dehydrogenase (ldh) and creatine kinase (ck) were determined in the frontal cortex, cerebellum, hippocampus and pons-medulla regions of hannover-wistar rats. |
2001-04-19 |
2023-08-12 |
rat |
| R J Cormier, S Mennerick, H Melbostad, C F Zorumsk. Basal levels of adenosine modulate mGluR5 on rat hippocampal astrocytes. Glia. vol 33. issue 1. 2001-04-12. PMID:11169789. |
on cultured hippocampal microislands containing only astrocytes, activation of metabotropic glutamate receptors (mglurs) with the specific agonist 1s,3r-acpd triggers ca2+ elevations that are potentiated by adenosine a1 receptor activation. |
2001-04-12 |
2023-08-12 |
rat |
| P Saransaari, S S Oj. Taurine and neural cell damage. Amino acids. vol 19. issue 3-4. 2001-04-05. PMID:11140356. |
excitotoxic concentrations of glutamate also potentiate taurine release in mouse hippocampal slices. |
2001-04-05 |
2023-08-12 |
mouse |
| J Hada, T Kaku, M H Jiang, K Morimoto, Y Hayashi, K Naga. Sodium nitroprusside-induced seizure and taurine release from rat hippocampus. Amino acids. vol 19. issue 3-4. 2001-04-05. PMID:11140358. |
we have recently reported that the nitric oxide (no) donor, sodium nitroprusside (snp), induces seizures which are associated with an increase in the basal release of aspartate and glutamate from rat hippocampus (kaku et al., 1998). |
2001-04-05 |
2023-08-12 |
rat |
| V Gundersen, F Fonnum, O P Ottersen, J Storm-Mathise. Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 21. issue 1. 2001-04-05. PMID:11149667. |
postembedding immunocytochemistry was used to localize aspartate, glutamate, gamma-aminobutyric acid (gaba), and glutamine in hippocampus and striatum during normo- and hypoglycemia in rat. |
2001-04-05 |
2023-08-12 |
rat |
| H Manev, T Uz, T Q. 5-Lipoxygenase and cyclooxygenase mRNA expression in rat hippocampus:early response to glutamate receptor activation by kainate. Experimental gerontology. vol 35. issue 9-10. 2001-03-29. PMID:11113602. |
5-lipoxygenase and cyclooxygenase mrna expression in rat hippocampus:early response to glutamate receptor activation by kainate. |
2001-03-29 |
2023-08-12 |
rat |
| H Manev, T Uz, T Q. 5-Lipoxygenase and cyclooxygenase mRNA expression in rat hippocampus:early response to glutamate receptor activation by kainate. Experimental gerontology. vol 35. issue 9-10. 2001-03-29. PMID:11113602. |
our results indicate that hippocampal expression of both 5lox and cox2 increases rather promptly when glutamate receptors are stimulated by kainate. |
2001-03-29 |
2023-08-12 |
rat |