| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M ROBSON, J B SENIO. THE 5-HYDROXYTRYPTAMINE CONTENT OF THE PLACENTA AND FOETUS DURING PREGNANCY IN MICE. British journal of pharmacology and chemotherapy. vol 22. 1996-12-01. PMID:14190473. |
treatment with cyproheptadine, a 5ht antagonist, did not delay parturition. |
1996-12-01 |
2023-08-12 |
mouse |
| D B AATER, C PETRIE, D A WATKINSO. EFFECT OF 5-HYDROXYTRYPTAMINE AND CYPROHEPTADINE ON TUMOUR BLOOD FLOW; ESTIMATION BY RATE OF COOLING AFTER MICROWAVE DIATHERMY. Acta radiologica: therapy, physics, biology. vol 3. 1996-12-01. PMID:14295469. |
effect of 5-hydroxytryptamine and cyproheptadine on tumour blood flow; estimation by rate of cooling after microwave diathermy. |
1996-12-01 |
2023-08-12 |
Not clear |
| T Mitsuma, M Kayama, Y Yokoi, N Rhue, M Izumi, S Takatsu, K Adachi, Y Hirooka, T Nogimor. Effects of serotonin on the release of thyrotropin-releasing hormone from the rat retina in vitro. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 28. issue 5. 1996-11-14. PMID:8738109. |
the trh release from the rat retina was inhibited significantly in a dose-related manner with the addition of serotonin and enhanced with cyproheptadine. |
1996-11-14 |
2023-08-12 |
rat |
| T Mitsuma, M Kayama, Y Yokoi, N Rhue, M Izumi, S Takatsu, K Adachi, Y Hirooka, T Nogimor. Effects of serotonin on the release of thyrotropin-releasing hormone from the rat retina in vitro. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 28. issue 5. 1996-11-14. PMID:8738109. |
the inhibitory effect of serotonin on trh release from the retina was blocked with the addition of cyproheptadine. |
1996-11-14 |
2023-08-12 |
rat |
| R Sakakibara, T Fukutake, K Kita, T Hattor. Treatment of primary erythromelalgia with cyproheptadine. Journal of the autonomic nervous system. vol 58. issue 1-2. 1996-10-24. PMID:8740669. |
the 5-ht and histamine antagonist cyproheptadine effectively relieved the burning pain and increased skin temperature. |
1996-10-24 |
2023-08-12 |
Not clear |
| L L Stark, A R Mercer, N J Emptage, T J Care. Pharmacological and kinetic characterization of two functional classes of serotonergic modulation in Aplysia sensory neurons. Journal of neurophysiology. vol 75. issue 2. 1996-10-10. PMID:8714658. |
based on a previously described dissociation of some of these modulatory effects, revealed with the 5ht-receptor antagonist, cyproheptadine, we investigated whether a similar dissociation could be found by systematically varying the concentration of the endogenous agonist, 5ht. |
1996-10-10 |
2023-08-12 |
aplysia |
| M J Doughty, W M Lyl. Medications used to prevent migraine headaches and their potential ocular adverse effects. Optometry and vision science : official publication of the American Academy of Optometry. vol 72. issue 12. 1996-10-03. PMID:8749335. |
those drugs that are administered for the purpose of reducing the frequency or severity of migraine attacks are classified according to whether they act on the cerebral vasculature primarily at serotonin (5-ht2) receptors (e.g., methysergide, cyproheptadine, and pizotyline), beta adrenergic (primarily beta-2) receptors (e.g., propranolol and timolol), via central nervous system (cns) adrenergic (alpha-2) receptors (e.g., clonidine), or calcium channels (e.g., flunarizine). |
1996-10-03 |
2023-08-12 |
Not clear |
| L S Lin, M T Li. Hypothalamic serotonin release and raised blood pressure after raphe nuclei stimulation in rats. Brain research bulletin. vol 39. issue 5. 1996-09-11. PMID:8705318. |
the dr stimulation-induced hypertension, tachycardia, or increased hypothalamic 5-ht release were attenuated by prior destruction of the ascending serotonergic system produced by icv injection of 5,7-dihydroxytryptamine and by prior blockade of postsynaptic serotonergic receptors produced by intrahypothalamic injection of 5-ht2 antagonists, cyproheptadine and ketanserin. |
1996-09-11 |
2023-08-12 |
rat |
| D Aizenberg, Z Zemishlany, A Weizma. Cyproheptadine treatment of sexual dysfunction induced by serotonin reuptake inhibitors. Clinical neuropharmacology. vol 18. issue 4. 1996-08-07. PMID:8665544. |
cyproheptadine treatment of sexual dysfunction induced by serotonin reuptake inhibitors. |
1996-08-07 |
2023-08-12 |
Not clear |
| H Y Lei, S H Lee, S H Lei. Antigen-induced anaphylactic death in mice. International archives of allergy and immunology. vol 109. issue 4. 1996-07-09. PMID:8634527. |
the bsa-induced anaphylactic death could be prevented by pretreating icr mice with cyproheptadine (histamine and serotonin antagonist) or diphenhydramine (histamine antagonist) and ketanserin (serotonin antagonist). |
1996-07-09 |
2023-08-12 |
mouse |
| K A Spore. The serotonin syndrome. Implicated drugs, pathophysiology and management. Drug safety. vol 13. issue 2. 1995-12-19. PMID:7576268. |
methysergide and cyproheptadine appear to be useful adjuncts in treating the serotonin syndrome. |
1995-12-19 |
2023-08-12 |
Not clear |
| H W Cole, C E Brown, D E Magee, C Magee, R E Roudebush, H U Bryan. Serotonin-induced paw edema in the rat: pharmacological profile. General pharmacology. vol 26. issue 2. 1995-12-06. PMID:7590099. |
a mixed 5-ht/histamine antagonist, cyproheptadine, also produced a nearly complete inhibition of the 5-ht response with an approximate ed50 of 1.3 mg/kg. |
1995-12-06 |
2023-08-12 |
rat |
| Y Fischer, J Thomas, J Kamp, E Jüngling, H Rose, Carpéné, H Kammermeie. 5-hydroxytryptamine stimulates glucose transport in cardiomyocytes via a monoamine oxidase-dependent reaction. The Biochemical journal. vol 311 ( Pt 2). 1995-11-28. PMID:7487898. |
the effect of 5-ht was not affected by (i) the 5-ht receptor antagonists methysergide (1 microm), ketanserin (1 microm), cyproheptadine (1 microm), mdl 72222 (1 microm) or ics 205-930 (3 microm), nor by (ii) the adrenergic receptor antagonists prazosin (1 microm), yohimbine (1 microm) or propranolol (5 microm), nor by (iii) the dopaminergic antagonists sch 23390 (1 microm) or haloperidol (1 microm). |
1995-11-28 |
2023-08-12 |
rat |
| K C Mill. Serotonin syndrome. American family physician. vol 52. issue 5. 1995-11-01. PMID:7572570. |
patients with serotonin syndrome usually respond to discontinuation of drug therapy and supportive care alone, but they may require treatment with a specific antiserotonergic drug such as cyproheptadine, methysergide and/or propranolol. |
1995-11-01 |
2023-08-12 |
Not clear |
| T H Tsai, T F Lee, C F Chen, L C Wan. Modulatory effects of magnolol on potassium-stimulated 5-hydroxytryptamine release from rat cortical and hippocampal slices. Neuroscience letters. vol 186. issue 1. 1995-07-14. PMID:7783947. |
the inhibitory effect of magnolol on k(+)-stimulated 5-ht release from the cortex was not affected by either antagonists (metergoline, propranolol, and cyproheptadine) (0.01-10 microm) of various 5-ht receptor subtypes or the voltage-dependent sodium channel blocker tetrodotoxin (1 microm). |
1995-07-14 |
2023-08-12 |
rat |
| C S Venugopalan, E P Holmes, K M Kleino. Evidence for serotonin involvement in the NANC excitatory neurotransmission in the catfish intestine. Journal of autonomic pharmacology. vol 15. issue 1. 1995-06-09. PMID:7538135. |
three types of serotonin receptor antagonists, namely methiothepin (predominantly a 5-ht1 antagonist), ketanserin (a selective 5-ht2 antagonist), methysergide and cyproheptadine (predominantly 5-ht2 blockers) and metoclopramide (a selective 5-ht3 blocker) were tested for their effectiveness against serotonin and efs-induced contractions. |
1995-06-09 |
2023-08-12 |
Not clear |
| C S Venugopalan, E P Holmes, K M Kleino. Evidence for serotonin involvement in the NANC excitatory neurotransmission in the catfish intestine. Journal of autonomic pharmacology. vol 15. issue 1. 1995-06-09. PMID:7538135. |
methiothepin, methysergide, cyproheptadine and metoclopramide produced significant blockade of the response to serotonin, whereas only methiothepin and cyproheptadine produced blockade of efs-induced response. |
1995-06-09 |
2023-08-12 |
Not clear |
| D N Velázquez Martínez, M Valencia Flores, M López Cabrera, J E Villarrea. Effects of indorenate on food intake: a comparison with fenfluramine and amphetamine. Psychopharmacology. vol 117. issue 1. 1995-05-25. PMID:7724707. |
the serotonin antagonists cinanserin, cyproheptadine, methergoline and methysergide effectively prevented the decrease in food intake produced by indorenate and fenfluramine. |
1995-05-25 |
2023-08-12 |
Not clear |
| M A Cheido, G V Idov. Participation of opiate delta-receptors in immunomodulation. Neuroscience and behavioral physiology. vol 24. issue 6. 1995-05-16. PMID:7715767. |
the activation of the opiate delta-receptors by the highly specific agonist dslet evokes an immunoinhibitory effect in cba mice which disappears with preliminary blockade of s2 serotonin receptors by cyproheptadine. |
1995-05-16 |
2023-08-12 |
mouse |
| S Le Corre, L Segu, M Caldani, P Cheminea. Differences in ketanserin binding in the ventromedial hypothalamus of ewes responsive or refractory to short days. Neuroendocrinology. vol 60. issue 6. 1995-05-02. PMID:7700502. |
the displacement studies from the cortex slices showed that the 5ht antagonists such as methysergide, ketanserin, cyproheptadine and spiperone competed with the labelled ligand at nanomolar concentrations whereas serotonin was less active. |
1995-05-02 |
2023-08-12 |
Not clear |