| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chao-Ji Yu, Meng Wang, Rui-Yang Li, Tao Wei, Han-Chen Yang, Yun-Si Yin, Ying-Xin Mi, Qi Qin, Yi Tan. TREM2 and Microglia Contribute to the Synaptic Plasticity: from Physiology to Pathology. Molecular neurobiology. 2022-11-01. PMID:36318443. |
numerous studies have proven that microglia can participate in the occurrence and progression of neurodegenerative diseases (ndds), such as alzheimer's disease (ad), by regulating synaptic plasticity. |
2022-11-01 |
2023-08-14 |
Not clear |
| Yelizhati Ruzha, Junjun Ni, Zhenzhen Quan, Hui Li, Hong Qin. Role of Vitronectin and Its Receptors in Neuronal Function and Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293243. |
moreover, evidence suggests that vtn is associated with neurodegenerative diseases, such as alzheimer's disease, but its function has not been fully understood. |
2022-10-27 |
2023-08-14 |
Not clear |
| María Pilar de Torre, Rita Yolanda Cavero, María Isabel Calv. Anticholinesterase Activity of Selected Medicinal Plants from Navarra Region of Spain and a Detailed Phytochemical Investigation of Molecules (Basel, Switzerland). vol 27. issue 20. 2022-10-27. PMID:36296692. |
anticholinesterase activity of selected medicinal plants from navarra region of spain and a detailed phytochemical investigation of alzheimer's disease is a neurodegenerative disease characterized by progressive memory loss and cognitive impairment due to a severe loss of cholinergic neurons in specific brain areas. |
2022-10-27 |
2023-08-14 |
Not clear |
| Javier Andrés Muñiz, Carolina Lucía Facal, Leandro Urrutia, Ramiro Clerici-Delville, Ana Damianich, Juan E Ferrario, Germán Falasco, María Elena Aval. SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy. Frontiers in bioengineering and biotechnology. vol 10. 2022-10-24. PMID:36277399. |
abnormal tau metabolism leads to neurodegenerative diseases named tauopathies, such as alzheimer's disease and frontotemporal dementia. |
2022-10-24 |
2023-08-14 |
human |
| E A Kovalenko, E V Makhnovich, N A Osinovskaya, A N Bogolepov. [Focused ultrasound as a non-invasive method with therapeutic potential in patients with Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 122. issue 10. 2022-10-24. PMID:36279227. |
alzheimer's disease (ad) is a common, progressive neurodegenerative disease characterized by abnormal deposition of β-amyloid (aβ) and hyperphosphorylated tau protein. |
2022-10-24 |
2023-08-14 |
Not clear |
| Pijush Chakraborty, Markus Zweckstette. Phase separation of the microtubule-associated protein tau. Essays in biochemistry. 2022-10-17. PMID:36251053. |
the aggregation and misfolding of the neuronal microtubule-associated protein tau is closely linked to the pathology of alzheimer's disease and several other neurodegenerative diseases. |
2022-10-17 |
2023-08-14 |
Not clear |
| Lenka Hromadkova, Mohammad Khursheed Siddiqi, He Liu, Jiri G Safa. Populations of Tau Conformers Drive Prion-like Strain Effects in Alzheimer's Disease and Related Dementias. Cells. vol 11. issue 19. 2022-10-14. PMID:36230957. |
recent findings of diverse populations of prion-like conformers of misfolded tau protein expand the prion concept to alzheimer's disease (ad) and monogenic frontotemporal lobar degeneration (ftld)-mapt p301l, and suggest that distinct strains of misfolded proteins drive the phenotypes and progression rates in many neurodegenerative diseases. |
2022-10-14 |
2023-08-14 |
human |
| Rose Chesworth, David Cheng, Chloe Staub, Tim Kar. Effect of long-term cannabidiol on learning and anxiety in a female Alzheimer's disease mouse model. Frontiers in pharmacology. vol 13. 2022-10-14. PMID:36238565. |
cannabidiol is a promising potential therapeutic for neurodegenerative diseases, including alzheimer's disease (ad). |
2022-10-14 |
2023-08-14 |
mouse |
| Duo Yun, Yajie Wang, Yuyu Zhang, Mengzhen Jia, Tianzhi Xie, Yihang Zhao, Cong Yang, Weixuan Chen, Rui Guo, Xuebo Liu, Xiaoshuang Dai, Zhigang Liu, Tian Yua. Sesamol Attenuates Scopolamine-Induced Cholinergic Disorders, Neuroinflammation, and Cognitive Deficits in Mice. Journal of agricultural and food chemistry. 2022-10-14. PMID:36239029. |
alzheimer's disease (ad) is a neurodegenerative disease, characterized by memory loss and cognitive deficits accompanied by neuronal damage and cholinergic disorders. |
2022-10-14 |
2023-08-14 |
mouse |
| Elisa Landucci, Costanza Mazzantini, Daniele Lana, Maura Calvani, Giada Magni, Maria Grazia Giovannini, Domenico E Pellegrini-Giampietr. Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model. Neurobiology of disease. 2022-10-14. PMID:36240948. |
in the last years the interest on the non-psychoactive compounds present in cannabis sativa has massively increased, and cannabidiol (cbd) has been shown to be effective in the treatment of different types of neurological disorders and neurodegenerative diseases such as epilepsy, ischemia, multiple sclerosis and alzheimer's disease. |
2022-10-14 |
2023-08-14 |
Not clear |
| Shuji Wakatsuki, Toshiyuki Arak. Novel insights into the mechanism of reactive oxygen species-mediated neurodegeneration. Neural regeneration research. vol 18. issue 4. 2022-10-07. PMID:36204830. |
neurite degeneration, a major component of many neurodegenerative diseases, such as parkinson's disease, alzheimer's disease, and amyotrophic lateral sclerosis, is not part of the typical apoptosis signaling mechanism, but rather it appears that a self-destructive process is in action. |
2022-10-07 |
2023-08-14 |
Not clear |
| Emil W Westi, Emil Jakobsen, Caroline M Voss, Lasse K Bak, Lars H Pinborg, Blanca I Aldana, Jens V Anderse. Divergent Cellular Energetics, Glutamate Metabolism, and Mitochondrial Function Between Human and Mouse Cerebral Cortex. Molecular neurobiology. 2022-10-06. PMID:36201140. |
disruptions of brain energy and neurotransmitter metabolism are associated with several pathological conditions including neurodegenerative diseases such as alzheimer's disease. |
2022-10-06 |
2023-08-14 |
mouse |
| Fengjuan Jiao, Bojie Zhou, Lingyan Men. The regulatory mechanism and therapeutic potential of transcription factor EB in neurodegenerative diseases. CNS neuroscience & therapeutics. 2022-10-03. PMID:36184826. |
transcription factor eb (tfeb), a major regulator of alp, has emerged as a leading factor in addressing neurodegenerative disease pathology, including alzheimer's disease (ad), parkinson's disease (pd), polyq diseases, and amyotrophic lateral sclerosis (als). |
2022-10-03 |
2023-08-14 |
Not clear |
| Wei Xiong, Ye Liu, Heng Zhou, Shuili Jing, Yan He, Qingsong Y. Alzheimer's disease: Pathophysiology and dental pulp stem cells therapeutic prospects. Frontiers in cell and developmental biology. vol 10. 2022-10-03. PMID:36187488. |
alzheimer's disease (ad) is a destructive neurodegenerative disease with the progressive dysfunction, structural disorders and decreased numbers of neurons in the brain, which leads to long-term memory impairment and cognitive decline. |
2022-10-03 |
2023-08-14 |
Not clear |
| Alisa Cario, Sanjula P Wickramasinghe, Elizabeth Rhoades, Christopher L Berge. The N-terminal disease-associated R5L Tau mutation increases microtubule shrinkage rate due to disruption of microtubule-bound Tau patches. The Journal of biological chemistry. 2022-09-26. PMID:36162501. |
tau misregulation is associated with a class of neurodegenerative diseases, known as tauopathies, including progressive supranuclear palsy (psp), pick's disease, and alzheimer's disease. |
2022-09-26 |
2023-08-14 |
Not clear |
| Gemma Shireby, Emma L Dempster, Stefania Policicchio, Rebecca G Smith, Ehsan Pishva, Barry Chioza, Jonathan P Davies, Joe Burrage, Katie Lunnon, Dorothea Seiler Vellame, Seth Love, Alan Thomas, Keeley Brookes, Kevin Morgan, Paul Francis, Eilis Hannon, Jonathan Mil. DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types. Nature communications. vol 13. issue 1. 2022-09-24. PMID:36153390. |
alzheimer's disease (ad) is a chronic neurodegenerative disease characterized by the progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex. |
2022-09-24 |
2023-08-14 |
Not clear |
| Rosalía Fernández-Calle, Sabine C Konings, Javier Frontiñán-Rubio, Juan García-Revilla, Lluís Camprubí-Ferrer, Martina Svensson, Isak Martinson, Antonio Boza-Serrano, José Luís Venero, Henrietta M Nielsen, Gunnar K Gouras, Tomas Deierbor. APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases. Molecular neurodegeneration. vol 17. issue 1. 2022-09-24. PMID:36153580. |
apoe in the bullseye of neurodegenerative diseases: impact of the apoe genotype in alzheimer's disease pathology and brain diseases. |
2022-09-24 |
2023-08-14 |
human |
| Shashank Pandey, Michal Jirásko, Jan Lochman, Alexandr Chvátal, Magdalena Chottova Dvorakova, Radek Kučer. iPSCs in Neurodegenerative Disorders: A Unique Platform for Clinical Research and Personalized Medicine. Journal of personalized medicine. vol 12. issue 9. 2022-09-23. PMID:36143270. |
the contribution of humanipscs in the most common neurodegenerative diseases (e.g., parkinson's disease and alzheimer's disease, diabetic neuropathy, stroke, and spinal cord injury) were examined and ranked as per their published literature on pubmed. |
2022-09-23 |
2023-08-14 |
human |
| Javad Sharifi-Rad, Simona Rapposelli, Simona Sestito, Jesús Herrera-Bravo, Alejandra Arancibia-Diaz, Luis A Salazar, Balakyz Yeskaliyeva, Ahmet Beyatli, Gerardo Leyva-Gómez, Carlos González-Contreras, Eda Sönmez Gürer, Miquel Martorell, Daniela Calin. Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation. Journal of personalized medicine. vol 12. issue 9. 2022-09-23. PMID:36143299. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by a tangle-shaped accumulation of beta-amyloid peptide fragments and tau protein in brain neurons. |
2022-09-23 |
2023-08-14 |
Not clear |
| Haoran Jia, Tianwu Xi. Tracers progress for positron emission tomography imaging of glial-related disease. Journal of biomedical research. 2022-09-22. PMID:36131689. |
extensive studies have shown that astrocytes and microglia play an important role in neurodegenerative diseases, such as alzheimer's disease, parkinson's disease, huntington's disease, as well as glioma, epilepsy, ischemic stroke, and infections. |
2022-09-22 |
2023-08-14 |
human |