| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernando Gonzalez-Ortiz, Michael Turton, Przemysław R Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas K Karikar. Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration. Brain : a journal of neurology. 2022-12-26. PMID:36572122. |
notably, plasma/serum brain-derived tau correlated with neurofilament light only in alzheimer's disease but not in the other neurodegenerative diseases. |
2022-12-26 |
2023-08-14 |
human |
| Dong Liang, Meng Ning, Hang Xie, Xiaoyan He, Peigen Ren, Xiaohua Lei, Xuepei Zhan. Radiotherapy Side Effects: Comprehensive Proteomic Study Unraveled Neural Stem Cell Degenerative Differentiation upon Ionizing Radiation. Biomolecules. vol 12. issue 12. 2022-12-23. PMID:36551187. |
among these proteins, succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (sdha) and the acyl carrier protein, mitochondrial (ndufab1) were highly related to neurodegenerative diseases such as parkinson's disease, alzheimer's disease, and huntington's disease, illustrating the dual-character of nscs in cell differentiation: following exposure to ionizing radiation, the normal differentiation of nscs was compromised, and the upregulated oxidized proteins implied a degenerative differentiation trajectory. |
2022-12-23 |
2023-08-14 |
Not clear |
| Yanan Zhu, Lauren Gandy, Fuming Zhang, Jian Liu, Chunyu Wang, Laura J Blair, Robert J Linhardt, Lianchun Wan. Heparan Sulfate Proteoglycans in Tauopathy. Biomolecules. vol 12. issue 12. 2022-12-23. PMID:36551220. |
tauopathies are a class of neurodegenerative diseases, including alzheimer's disease, and are characterized by intraneuronal tau inclusion in the brain and the patient's cognitive decline with obscure pathogenesis. |
2022-12-23 |
2023-08-14 |
Not clear |
| Md Jakaria, Abdel A Belaidi, Adam Southon, Krista A Dent, Darius J R Lane, Ashley I Bush, Scott Ayto. Receptor-Independent Anti-Ferroptotic Activity of TrkB Modulators. International journal of molecular sciences. vol 23. issue 24. 2022-12-23. PMID:36555849. |
dysregulated brain-derived neurotrophic factor (bdnf)/tropomyosin receptor kinase b (trkb) signalling is implicated in several neurodegenerative diseases, including alzheimer's disease. |
2022-12-23 |
2023-08-14 |
Not clear |
| Ling Wu, Sidharth S Madhavan, Christopher Tan, Bin X. Hexameric Aggregation Nucleation Core Sequences and Diversity of Pathogenic Tau Strains. Pathogens (Basel, Switzerland). vol 11. issue 12. 2022-12-23. PMID:36558893. |
tau aggregation associates with multiple neurodegenerative diseases including alzheimer's disease and rare tauopathies such as pick's disease, progressive supranuclear palsy, and corticobasal degeneration. |
2022-12-23 |
2023-08-14 |
Not clear |
| Xibing He, Viet Hoang Man, Jie Gao, Junmei Wan. Investigation of the Structure of Full-Length Tau Proteins with Coarse-Grained and All-Atom Molecular Dynamics Simulations. ACS chemical neuroscience. 2022-12-23. PMID:36563129. |
tau proteins not only have many important biological functions but also are associated with several neurodegenerative diseases, such as parkinson's disease and alzheimer's disease (ad). |
2022-12-23 |
2023-08-14 |
Not clear |
| Carol J Huseby, Elaine Delvaux, Danielle L Brokaw, Paul D Colema. Blood RNA transcripts reveal similar and differential alterations in fundamental cellular processes in Alzheimer's disease and other neurodegenerative diseases. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022-12-21. PMID:36541444. |
dysfunctional processes in alzheimer's disease and other neurodegenerative diseases lead to neural degeneration in the central and peripheral nervous system. |
2022-12-21 |
2023-08-14 |
Not clear |
| Itzhak Fische. Evolutionary perspective of Big tau structure: 4a exon variants of MAPT. Frontiers in molecular neuroscience. vol 15. 2022-12-19. PMID:36533137. |
tau plays important roles in modulating microtubule dynamics, axonal transport, synaptic plasticity, and dna repair, and has also been associated with neurodegenerative diseases (tauopathies) including alzheimer's disease and frontotemporal dementia. |
2022-12-19 |
2023-08-14 |
human |
| Ye Man Tang, Nisha S Pulimood, Stefano Stifan. Comparing the Characteristics of Microglia Preparations Generated Using Different Human iPSC-Based Differentiation Methods to Model Neurodegenerative Diseases. ASN neuro. vol 14. 2022-12-16. PMID:36524236. |
dysregulated microglia activation is a hallmark of nervous system disorders including neurodegenerative diseases such as amyotrophic lateral sclerosis (als) and alzheimer's disease. |
2022-12-16 |
2023-08-14 |
human |
| b' Simone Lista, Andrea Vergallo, Stefan J Teipel, Pablo Lemercier, Filippo Sean Giorgi, Audrey Gabelle, Francesco Garaci, Nicola B Mercuri, Claudio Babiloni, Bhakta Prasad Gaire, Yosef Koronyo, Maya Koronyo-Hamaoui, Harald Hampel, Robert Nistic\\xc3\\xb. Determinants of approved acetylcholinesterase inhibitor response outcomes in Alzheimer\'s disease: relevance for precision medicine in neurodegenerative diseases. Ageing research reviews. 2022-12-16. PMID:36526257.' |
determinants of approved acetylcholinesterase inhibitor response outcomes in alzheimer's disease: relevance for precision medicine in neurodegenerative diseases. |
2022-12-16 |
2023-08-14 |
Not clear |
| b' Simone Lista, Andrea Vergallo, Stefan J Teipel, Pablo Lemercier, Filippo Sean Giorgi, Audrey Gabelle, Francesco Garaci, Nicola B Mercuri, Claudio Babiloni, Bhakta Prasad Gaire, Yosef Koronyo, Maya Koronyo-Hamaoui, Harald Hampel, Robert Nistic\\xc3\\xb. Determinants of approved acetylcholinesterase inhibitor response outcomes in Alzheimer\'s disease: relevance for precision medicine in neurodegenerative diseases. Ageing research reviews. 2022-12-16. PMID:36526257.' |
acetylcholinesterase inhibitors (chei) are the global standard of care for the symptomatic treatment of alzheimer's disease (ad) and show significant positive effects in neurodegenerative diseases with cognitive and behavioral symptoms. |
2022-12-16 |
2023-08-14 |
Not clear |
| Sevilay Ayyildiz, Halil Aziz Velioglu, Behcet Ayyildiz, Bernis Sutcubasi, Lutfu Hanoglu, Zubeyir Bayraktaroglu, Suleyman Yildirim, Alper Atasever, Burak Yulu. Differentiation of claustrum resting-state functional connectivity in healthy aging, Alzheimer's disease, and Parkinson's disease. Human brain mapping. 2022-12-14. PMID:36515182. |
although the claustrum has been involved in several neurodegenerative diseases, specific changes in connections of the claustrum remain unclear in alzheimer's disease (ad), and parkinson's disease (pd). |
2022-12-14 |
2023-08-14 |
human |
| Ganggang Miao, Danping Zhuo, Xue Han, Wentao Yao, Chuan Liu, Hanyuan Liu, Hongyong Cao, Yangbai Sun, Zhiqiang Chen, Tingting Fen. From degenerative disease to malignant tumors: Insight to the function of ApoE. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2022-12-14. PMID:36516696. |
due to genetic polymorphisms of apoe (ε2, ε3, and ε4), its three common structural isoforms (apoe2, apoe3, apoe4) are also associated with the risk of many diseases, especially degenerative diseases, such as vascular degenerative diseases including atherosclerosis (as), coronary heart disease (chd), and neurodegenerative disease like alzheimer's disease (ad). |
2022-12-14 |
2023-08-14 |
Not clear |
| Arjuna Abitbol, Brody Mallard, Evelin Tiralongo, Joe Tiralong. Mushroom Natural Products in Neurodegenerative Disease Drug Discovery. Cells. vol 11. issue 23. 2022-12-11. PMID:36497196. |
neuroinflammation is a common feature of neurodegenerative diseases such as alzheimer's disease, parkinson's disease, huntington's disease, and multiple sclerosis, and is associated with the activation of the nlrp3 inflammasome, which in turn leads to neurodegeneration. |
2022-12-11 |
2023-08-14 |
Not clear |
| Tianqing Liu, Yuying Li, Yan Wang, Xiao-Xin Yan, Jiapei Dai, Mengchao Cu. Discovery and evaluation of aza-fused tricyclic derivatives for detection of Tau pathology in Alzheimer's disease. European journal of medicinal chemistry. vol 246. 2022-12-09. PMID:36493618. |
for various neurodegenerative diseases, including alzheimer's disease (ad), the abnormal aggregation of tau is not only the predominant contributing factor but also a major biomarker for disease diagnosis. |
2022-12-09 |
2023-08-14 |
Not clear |
| Xin Liu, Zhao-Yan Cheng, Yan-Feng Li, Chao Liu, Chen Wang, Gong Xiao-Jian, Ling H. Dopamine D2 receptor agonist Bromocriptine ameliorates Aβ European journal of pharmacology. 2022-12-05. PMID:36470446. |
dopamine d2 receptor agonist bromocriptine ameliorates aβ alzheimer's disease (ad) is the most common neurodegenerative disease, which lacks disease-modifying therapeutics so far. |
2022-12-05 |
2023-08-14 |
Not clear |
| Feng Gao, Jingyi Sun, Minmin Yao, Yanan Song, Hui Yi, Mingfeng Yang, Qingbin Ni, Jiming Kong, Hui Yuan, Baoliang Sun, Ying Wan. SERS "hot spot" enhance-array assay for misfolded SOD1 correlated with white matter lesions and aging. Analytica chimica acta. vol 1238. 2022-12-04. PMID:36464456. |
misfolding of superoxide dismutase-1 (sod1) has been correlated with many neurodegenerative diseases, such as amyotrophic lateral sclerosis's and alzheimer's among others. |
2022-12-04 |
2023-08-14 |
Not clear |
| Qu Tian, Yang An, Melissa H Kitner Triolo, Christos Davatzikos, Stephanie A Studenski, Luigi Ferrucci, Susan M Resnic. Associations of Olfaction With Longitudinal Trajectories of Brain Volumes and Neuropsychological Function in Older Adults. Neurology. 2022-12-02. PMID:36460474. |
olfactory function declines with aging and olfactory deficits are one of the earliest features of neurodegenerative diseases, such as parkinson's disease and alzheimer's disease. |
2022-12-02 |
2023-08-14 |
Not clear |
| Christella Gordon-Kim, Allisandra Rha, George A Poppitz, Jillian Smith-Carpenter, Regina Luu, Alexis B Roberson, Russell Conklin, Alexis Blake, David G Lyn. Polyanion order controls liquid-to-solid phase transition in peptide/nucleic acid co-assembly. Frontiers in molecular biosciences. vol 9. 2022-12-01. PMID:36452451. |
inspired by the highly dynamic character of these organelles and the recent studies that atp both inhibits and templates phase separation of the fused in sarcoma (fus) protein implicated in several neurodegenerative diseases, we explored the rna templated ordering of a single motif of the aβ peptide of alzheimer's disease. |
2022-12-01 |
2023-08-14 |
Not clear |
| Irene Villalón-García, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Marta Talaverón-Rey, Juan M Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A Sánchez-Alcáza. Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration. Neural regeneration research. vol 18. issue 6. 2022-12-01. PMID:36453394. |
lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as alzheimer's, parkinson's, and huntington's diseases, or neurodegeneration with brain iron accumulation disorders. |
2022-12-01 |
2023-08-14 |
Not clear |