| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Feng Gao, Jingyi Sun, Minmin Yao, Yanan Song, Hui Yi, Mingfeng Yang, Qingbin Ni, Jiming Kong, Hui Yuan, Baoliang Sun, Ying Wan. SERS "hot spot" enhance-array assay for misfolded SOD1 correlated with white matter lesions and aging. Analytica chimica acta. vol 1238. 2022-12-04. PMID:36464456. |
misfolding of superoxide dismutase-1 (sod1) has been correlated with many neurodegenerative diseases, such as amyotrophic lateral sclerosis's and alzheimer's among others. |
2022-12-04 |
2023-08-14 |
Not clear |
| Qu Tian, Yang An, Melissa H Kitner Triolo, Christos Davatzikos, Stephanie A Studenski, Luigi Ferrucci, Susan M Resnic. Associations of Olfaction With Longitudinal Trajectories of Brain Volumes and Neuropsychological Function in Older Adults. Neurology. 2022-12-02. PMID:36460474. |
olfactory function declines with aging and olfactory deficits are one of the earliest features of neurodegenerative diseases, such as parkinson's disease and alzheimer's disease. |
2022-12-02 |
2023-08-14 |
Not clear |
| Christella Gordon-Kim, Allisandra Rha, George A Poppitz, Jillian Smith-Carpenter, Regina Luu, Alexis B Roberson, Russell Conklin, Alexis Blake, David G Lyn. Polyanion order controls liquid-to-solid phase transition in peptide/nucleic acid co-assembly. Frontiers in molecular biosciences. vol 9. 2022-12-01. PMID:36452451. |
inspired by the highly dynamic character of these organelles and the recent studies that atp both inhibits and templates phase separation of the fused in sarcoma (fus) protein implicated in several neurodegenerative diseases, we explored the rna templated ordering of a single motif of the aβ peptide of alzheimer's disease. |
2022-12-01 |
2023-08-14 |
Not clear |
| Irene Villalón-García, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Marta Talaverón-Rey, Juan M Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A Sánchez-Alcáza. Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration. Neural regeneration research. vol 18. issue 6. 2022-12-01. PMID:36453394. |
lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as alzheimer's, parkinson's, and huntington's diseases, or neurodegeneration with brain iron accumulation disorders. |
2022-12-01 |
2023-08-14 |
Not clear |
| Anna Atlante, Giuseppina Amadoro, Valentina Latina, Daniela Valent. Therapeutic Potential of Targeting Mitochondria for Alzheimer's Disease Treatment. Journal of clinical medicine. vol 11. issue 22. 2022-11-26. PMID:36431219. |
alzheimer's disease (ad), a chronic and progressive neurodegenerative disease, is characterized by memory and cognitive impairment and by the accumulation in the brain of abnormal proteins, more precisely beta-amyloid (β-amyloid or aβ) and tau proteins. |
2022-11-26 |
2023-08-14 |
Not clear |
| Mehboob Hoque, Arijit Samanta, Syed Sahajada Mahafujul Alam, Torki A Zughaibi, Mohammad Amjad Kamal, Shams Tabre. Nanomedicine-based immunotherapy for Alzheimer's Disease. Neuroscience and biobehavioral reviews. 2022-11-26. PMID:36435391. |
alzheimer's disease (ad) is the most prevalent neurodegenerative disease caused by the deposition of amyloid β (aβ) fibrils forming extracellular plaques and the development of neurofibrillary tangles (nft) of intracellular hyperphosphorylated tau protein. |
2022-11-26 |
2023-08-14 |
Not clear |
| Dena Nuwaylati, Basmah Eldakhakhny, Abdulhadi Bima, Hussein Sakr, Ayman Elsamanoud. Low-Carbohydrate High-Fat Diet: A SWOC Analysis. Metabolites. vol 12. issue 11. 2022-11-24. PMID:36422267. |
insulin resistance (ir) plays a role in the pathogenesis of many diseases, such as type 2 diabetes mellitus, cardiovascular disease, non-alcoholic fatty liver disease, obesity, and neurodegenerative diseases, including alzheimer's disease. |
2022-11-24 |
2023-08-14 |
human |
| Francesco Limone, Joseph R Klim, Daniel A Morde. Pluripotent stem cell strategies for rebuilding the human brain. Frontiers in aging neuroscience. vol 14. 2022-11-21. PMID:36408113. |
in this review, we cover advances in methods used to differentiate human pluripotent stem cells into several highly specialized types of neurons, including cholinergic, dopaminergic, and motor neurons, and the potential clinical applications of stem cell-derived neurons for common neurodegenerative diseases, including alzheimer's disease, parkinson's disease, huntington's disease, ataxia, and amyotrophic lateral sclerosis. |
2022-11-21 |
2023-08-14 |
human |
| Sadhana Sharma, Curtis Borski, Jessica Hanson, Micklaus A Garcia, Christopher D Link, Charles Hoeffer, Anushree Chatterjee, Prashant Nagpa. Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine. ACS chemical neuroscience. 2022-11-21. PMID:36410860. |
however, chronic neuroinflammation leading to the activation of immune cells like microglia and astrocytes causes damage to the nervous tissue, and it is causally linked to a range of neurodegenerative diseases such as alzheimer's diseases (ad), multiple sclerosis (ms), parkinson's disease (pd), and many others. |
2022-11-21 |
2023-08-14 |
mouse |
| Yu Li, Yuanyuan Zhao, Xiaona Li, Liuqun Zhai, Hua Zheng, Ying Yan, Qiang Fu, Jinlian Ma, Haier Fu, Zhenqiang Zhang, Zhonghua L. Biological and therapeutic role of LSD1 in Alzheimer's diseases. Frontiers in pharmacology. vol 13. 2022-11-17. PMID:36386192. |
alzheimer's disease (ad) is a common chronic neurodegenerative disease characterized by cognitive learning and memory impairments, however, current treatments only provide symptomatic relief. |
2022-11-17 |
2023-08-14 |
Not clear |
| Karthikeyan Selvarasu, Abhay Kumar Singh, Ashok Iyaswamy, Sravan Gopalkrishnashetty Sreenivasmurthy, Senthilkumar Krishnamoorthi, Amal Kanti Bera, Jian-Dong Huang, Siva Sundara Kumar Durairaja. Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer's disease and tauopathy models. Frontiers in molecular biosciences. vol 9. 2022-11-17. PMID:36387285. |
many neurodegenerative diseases, such as alzheimer's disease (ad) and frontotemporal dementia with parkinsonism linked to chromosome 17, are characterized by tau pathology. |
2022-11-17 |
2023-08-14 |
mouse |
| YuHong Fu, Ying He, Katherine Phan, Surabhi Bhatia, Russell Pickford, Ping Wu, Nicolas Dzamko, Glenda M Halliday, Woojin Scott Ki. Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain. Acta neuropathologica communications. vol 10. issue 1. 2022-11-15. PMID:36376990. |
we were therefore interested in the manifestation of lipid peroxidation in synucleinopathies, a group of neurodegenerative diseases characterized by the central pathology of α-synuclein aggregates, including parkinson's disease, multiple system atrophy, dementia with lewy bodies and alzheimer's disease with lewy bodies. |
2022-11-15 |
2023-08-14 |
Not clear |
| Yuan Li, Haifeng Zhang, Weihong Long, Menghan Gao, Weiying Guo, Lu Y. Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation Aging. vol 14. 2022-11-15. PMID:36378718. |
inhibition of nlrp3 and golph3 ameliorates diabetes-induced neuroinflammation golgi stress has been observed in various neurodegenerative diseases, such as alzheimer's disease and parkinson's disease. |
2022-11-15 |
2023-08-14 |
Not clear |
| Dahbia Yatoui, Philipp O Tsvetkov, Romain La Rocca, Viktoriia E Baksheeva, Diane Allegro, Gilles Breuzard, Géraldine Ferracci, Deborah Byrne, François Devre. Binding of two zinc ions promotes liquid-liquid phase separation of Tau. International journal of biological macromolecules. 2022-11-14. PMID:36375666. |
tau is a naturally disordered microtubule associated protein which forms intraneuronal aggregates in several neurodegenerative diseases including alzheimer's disease (ad). |
2022-11-14 |
2023-08-14 |
Not clear |
| Sam J Washer, Marta Perez-Alcantara, Yixi Chen, Juliette Steer, William S James, Gosia Trynka, Andrew R Bassett, Sally A Cowle. Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia. Scientific reports. vol 12. issue 1. 2022-11-14. PMID:36376339. |
there is increasing genetic evidence for the role of microglia in neurodegenerative diseases, including alzheimer's, parkinson's, and motor neuron disease. |
2022-11-14 |
2023-08-14 |
human |
| Lei Gu, Jacky M K Kwong, Joseph Caprioli, Natik Pir. Visual Function and Survival of Injured Retinal Ganglion Cells in Aged Rbfox1 Knockout Animals. Cells. vol 11. issue 21. 2022-11-11. PMID:36359797. |
rbfox1 has been associated with neurodevelopmental and neurological conditions as well as age-related neurodegenerative diseases such as alzheimer's and parkinson's. |
2022-11-11 |
2023-08-14 |
mouse |
| Ujala Sehar, Priyanka Rawat, Arubala P Reddy, Jonathan Kopel, P Hemachandra Redd. Amyloid Beta in Aging and Alzheimer's Disease. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36361714. |
alzheimer's disease (ad), is a progressive neurodegenerative disease that affects behavior, thinking, learning, and memory in elderly individuals. |
2022-11-11 |
2023-08-14 |
Not clear |
| Ling Wu, Nailya Gilyazova, John F Ervin, Shih-Hsiu J Wang, Bin X. Site-Specific Phospho-Tau Aggregation-Based Biomarker Discovery for AD Diagnosis and Differentiation. ACS chemical neuroscience. 2022-11-09. PMID:36350059. |
tau aggregates are present in multiple neurodegenerative diseases known as "tauopathies," including alzheimer's disease (ad), pick's disease (pid), progressive supranuclear palsy (psp), and corticobasal degeneration (cbd). |
2022-11-09 |
2023-08-14 |
human |
| Xiaoying Chen, David M Holtzma. Emerging roles of innate and adaptive immunity in Alzheimer's disease. Immunity. 2022-11-09. PMID:36351425. |
alzheimer's disease (ad) is the most common neurodegenerative disease, with characteristic extracellular amyloid-β (aβ) deposition and intracellular accumulation of hyperphosphorylated, aggregated tau. |
2022-11-09 |
2023-08-14 |
Not clear |
| Shenglong Guo, Qi Lei, Hena Guo, Qian Yang, Yanli Xue, Ruili Che. Edaravone Attenuates Aβ 1-42-Induced Inflammatory Damage and Ferroptosis in HT22 Cells. Neurochemical research. 2022-11-05. PMID:36333599. |
ferroptosis and neuroinflammation play a crucial role in the pathogenesis of alzheimer's disease (ad), and edaravone (eda) has been demonstrated to have anti-inflammatory, antioxidant and neuroprotective effects in neurodegenerative diseases. |
2022-11-05 |
2023-08-14 |
Not clear |