| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Akiyama, T Nishimura, H Kondo, K Ikeda, Y Hayashi, P L McGee. Expression of the receptor for macrophage colony stimulating factor by brain microglia and its upregulation in brains of patients with Alzheimer's disease and amyotrophic lateral sclerosis. Brain research. vol 639. issue 1. 1994-06-16. PMID:7514086. |
microglia constitutively expressed the receptor for csf-1 and its expression was upregulated in lesions of alzheimer's disease and amyotrophic lateral sclerosis. |
1994-06-16 |
2023-08-12 |
human |
| H Akiyama, K Ikeda, H Kondo, M Kato, P L McGee. Microglia express the type 2 plasminogen activator inhibitor in the brain of control subjects and patients with Alzheimer's disease. Neuroscience letters. vol 164. issue 1-2. 1994-05-09. PMID:8152607. |
microglia express the type 2 plasminogen activator inhibitor in the brain of control subjects and patients with alzheimer's disease. |
1994-05-09 |
2023-08-12 |
mouse |
| A Klegeris, D G Walker, P L McGee. Activation of macrophages by Alzheimer beta amyloid peptide. Biochemical and biophysical research communications. vol 199. issue 2. 1994-04-21. PMID:7510964. |
microglia (brain resident macrophages) have been found to be closely associated with beta amyloid containing plaques in brain tissue affected by alzheimer disease (ad). |
1994-04-21 |
2023-08-12 |
rat |
| A McRae, A Dahlström, R Polinsky, E A Lin. Cerebrospinal fluid microglial antibodies: potential diagnostic markers for immune mechanisms in Alzheimer's disease. Behavioural brain research. vol 57. issue 2. 1994-04-06. PMID:8117427. |
hallmark lesions of alzheimer's disease (ad) are filled with reactive immunocompetent microglia, suggesting that immunological aberrations may participate in the pathophysiology of this disorder. |
1994-04-06 |
2023-08-12 |
rat |
| R B Banati, J Gehrmann, C Czech, U Mönning, L L Jones, G König, K Beyreuther, G W Kreutzber. Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia. Glia. vol 9. issue 3. 1994-02-28. PMID:7507467. |
early and rapid de novo synthesis of alzheimer beta a4-amyloid precursor protein (app) in activated microglia. |
1994-02-28 |
2023-08-12 |
Not clear |
| R B Banati, J Gehrmann, C Czech, U Mönning, L L Jones, G König, K Beyreuther, G W Kreutzber. Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia. Glia. vol 9. issue 3. 1994-02-28. PMID:7507467. |
upon acute activation, microglia, the immuneffector cells of the brain parenchyma, express the amyloid precursor protein (app) that is otherwise prominent in pathological structures related to alzheimer's disease. |
1994-02-28 |
2023-08-12 |
Not clear |
| A R Korotzer, C J Pike, C W Cotma. beta-Amyloid peptides induce degeneration of cultured rat microglia. Brain research. vol 624. issue 1-2. 1994-01-13. PMID:8252383. |
microglia are often associated with senile plaques, a primary pathological hallmark of alzheimer's disease (ad) that consists largely of insoluble deposits of beta-amyloid (a beta) protein. |
1994-01-13 |
2023-08-12 |
rat |
| K Nakajima, S Kohsak. Functional roles of microglia in the brain. Neuroscience research. vol 17. issue 3. 1993-12-13. PMID:8233123. |
in this article, we discussed the association or roles of microglia in injury and in brain diseases such as alzheimer's disease, aids dementia complex, multiple sclerosis and ischemia. |
1993-12-13 |
2023-08-12 |
Not clear |
| E R Whittemore, A R Korotzer, A Etebari, C W Cotma. Carbachol increases intracellular free calcium in cultured rat microglia. Brain research. vol 621. issue 1. 1993-12-09. PMID:8106116. |
furthermore, since cholinergic fibers have been shown to infiltrate neuritic plaques in alzheimer's disease (ad) and microglia have been reported to be activated in plaques, these results suggest that interactions between select neurotransmitters and microglia may play a key role in neurodegenerative diseases. |
1993-12-09 |
2023-08-12 |
rat |
| A F Carpenter, P W Carpenter, W R Markesber. Morphometric analysis of microglia in Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 52. issue 6. 1993-12-08. PMID:8229079. |
morphometric analysis of microglia in alzheimer's disease. |
1993-12-08 |
2023-08-12 |
human |
| A F Carpenter, P W Carpenter, W R Markesber. Morphometric analysis of microglia in Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 52. issue 6. 1993-12-08. PMID:8229079. |
hla-dr-immunoreactive microglia were quantitated in the middle temporal gyrus of five late-stage patients with alzheimer's disease (ad) and five age-matched control subjects using ln3 immunocytochemistry and computerized morphometric image analysis. |
1993-12-08 |
2023-08-12 |
human |
| N S Peress, H B Fleit, E Perillo, R Kuljis, C Pezzull. Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease. Journal of neuroimmunology. vol 48. issue 1. 1993-12-03. PMID:8227309. |
identification of fc gamma ri, ii and iii on normal human brain ramified microglia and on microglia in senile plaques in alzheimer's disease. |
1993-12-03 |
2023-08-12 |
human |
| N S Peress, H B Fleit, E Perillo, R Kuljis, C Pezzull. Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease. Journal of neuroimmunology. vol 48. issue 1. 1993-12-03. PMID:8227309. |
we found fc gamma ri, ii and iii immunoreactivity in senile plaques and on ramified microglia throughout the cortex and white matter of normal and alzheimer's disease brains. |
1993-12-03 |
2023-08-12 |
human |
| H M Wisniewski, J Weige. Migration of perivascular cells into the neuropil and their involvement in beta-amyloid plaque formation. Acta neuropathologica. vol 85. issue 6. 1993-08-26. PMID:8337937. |
our recent ultrastructural studies of amyloid angiopathy in biopsy specimens from alzheimer's disease patients showed that perivascular cells and perivascular microglia are involved in the production of amyloid fibrils. |
1993-08-26 |
2023-08-12 |
Not clear |
| M Barcikowska, P P Liberski, J W Boellaard, P Brown, D C Gajdusek, H Budk. Microglia is a component of the prion protein amyloid plaque in the Gerstmann-Sträussler-Scheinker syndrome. Acta neuropathologica. vol 85. issue 6. 1993-08-26. PMID:8337941. |
the microglial cell has been demonstrated as component of the cerebral amyloid plaque of alzheimer's disease. |
1993-08-26 |
2023-08-12 |
Not clear |
| M N Gordo. Microglia and immune activation in Alzheimer's disease. The Journal of the Florida Medical Association. vol 80. issue 4. 1993-07-02. PMID:7685046. |
microglia and immune activation in alzheimer's disease. |
1993-07-02 |
2023-08-12 |
Not clear |
| S A Scott, S A Johnson, C Zarow, L S Perlmutte. Inability to detect beta-amyloid protein precursor mRNA in Alzheimer plaque-associated microglia. Experimental neurology. vol 121. issue 1. 1993-06-24. PMID:8495706. |
inability to detect beta-amyloid protein precursor mrna in alzheimer plaque-associated microglia. |
1993-06-24 |
2023-08-12 |
Not clear |
| S A Scott, S A Johnson, C Zarow, L S Perlmutte. Inability to detect beta-amyloid protein precursor mRNA in Alzheimer plaque-associated microglia. Experimental neurology. vol 121. issue 1. 1993-06-24. PMID:8495706. |
a close association between alzheimer senile plaques and microglia (the resident mononuclear phagocytic system cells of the brain) is well documented. |
1993-06-24 |
2023-08-12 |
Not clear |
| S A Scott, S A Johnson, C Zarow, L S Perlmutte. Inability to detect beta-amyloid protein precursor mRNA in Alzheimer plaque-associated microglia. Experimental neurology. vol 121. issue 1. 1993-06-24. PMID:8495706. |
recent demonstrations of interactions between immune-related factors and alzheimer lesions suggest that beta-app and its breakdown products, along with microglia and their secretory products, may work synergistically in an ad pathogenetic cascade. |
1993-06-24 |
2023-08-12 |
Not clear |
| R B Banati, G Rothe, G Valet, G W Kreutzber. Detection of lysosomal cysteine proteinases in microglia: flow cytometric measurement and histochemical localization of cathepsin B and L. Glia. vol 7. issue 2. 1993-03-15. PMID:8432559. |
detection of lysosomal cysteine proteinases in microglia: flow cytometric measurement and histochemical localization of cathepsin b and l. the activation and differentiation of microglia is a prominent pathophysiological process in numerous inflammatory and demyelinating diseases of the central nervous system, including alzheimer's disease and the aids encephalopathy. |
1993-03-15 |
2023-08-12 |
rat |