| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Sheng, R E Mrak, W S Griffi. Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages. Journal of neuropathology and experimental neurology. vol 56. issue 3. 1997-04-07. PMID:9056542. |
glial-neuronal interactions in alzheimer disease: progressive association of il-1alpha+ microglia and s100beta+ astrocytes with neurofibrillary tangle stages. |
1997-04-07 |
2023-08-12 |
Not clear |
| J G Sheng, R E Mrak, W S Griffi. Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages. Journal of neuropathology and experimental neurology. vol 56. issue 3. 1997-04-07. PMID:9056542. |
activated microglia, overexpressing interleukin-1 (il-1), and activated astrocytes, overexpressing s100beta, have been implicated in the formation and evolution of tau2-immunoreactive (tau2+) neuritic plaques in alzheimer disease. |
1997-04-07 |
2023-08-12 |
Not clear |
| J G Sheng, R E Mrak, W S Griffi. Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages. Journal of neuropathology and experimental neurology. vol 56. issue 3. 1997-04-07. PMID:9056542. |
in this study, we assessed the role of il-1alpha+ microglia and s100beta+ astrocytes in the pathogenesis of another cardinal histopathological feature of alzheimer disease: tau2+ neurofibrillary tangles. |
1997-04-07 |
2023-08-12 |
Not clear |
| J G Sheng, R E Mrak, W S Griffi. Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages. Journal of neuropathology and experimental neurology. vol 56. issue 3. 1997-04-07. PMID:9056542. |
the numbers of tangles in randomly selected fields of parahippocampal cortex from 11 alzheimer patients correlated with both the numbers of il-1alpha+ microglia and the numbers of s100beta+ astrocytes in these fields (r = 0.72, p < 0.02; r = 0.73, p = 0.01, respectively). |
1997-04-07 |
2023-08-12 |
Not clear |
| J G Sheng, R E Mrak, W S Griffi. Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages. Journal of neuropathology and experimental neurology. vol 56. issue 3. 1997-04-07. PMID:9056542. |
this progressive association of activated il-1alpha+ microglia and activated s100beta+ astrocytes with tau2+ tangle stages suggests a role for glial-neuronal interactions in the degeneration of tangle-bearing neurons in alzheimer disease. |
1997-04-07 |
2023-08-12 |
Not clear |
| A McRae, A Dahlström, E A Lin. Microglial in neurodegenerative disorders: emphasis on Alzheimer's disease. Gerontology. vol 43. issue 1-2. 1997-04-01. PMID:8996832. |
hallmark lesions of alzheimer's disease (ad) are filled with reactive immunocompetent microglia, suggesting that immunological aberrations may participate in the pathophysiology of this disorder. |
1997-04-01 |
2023-08-12 |
rat |
| T Saitoh, D Kang, M Mallory, R DeTeresa, E Maslia. Glial cells in Alzheimer's disease: preferential effect of APOE risk on scattered microglia. Gerontology. vol 43. issue 1-2. 1997-04-01. PMID:8996833. |
glial cells in alzheimer's disease: preferential effect of apoe risk on scattered microglia. |
1997-04-01 |
2023-08-12 |
Not clear |
| B Drache, G E Diehl, K Beyreuther, L S Perlmutter, G Köni. Bcl-xl-specific antibody labels activated microglia associated with Alzheimer's disease and other pathological states. Journal of neuroscience research. vol 47. issue 1. 1997-03-26. PMID:8981243. |
bcl-xl-specific antibody labels activated microglia associated with alzheimer's disease and other pathological states. |
1997-03-26 |
2023-08-12 |
human |
| P L DiPatre, B B Gelma. Microglial cell activation in aging and Alzheimer disease: partial linkage with neurofibrillary tangle burden in the hippocampus. Journal of neuropathology and experimental neurology. vol 56. issue 2. 1997-03-18. PMID:9034367. |
microglial cell activation in aging and alzheimer disease: partial linkage with neurofibrillary tangle burden in the hippocampus. |
1997-03-18 |
2023-08-12 |
human |
| B L Fiebich, K Biber, K Lieb, D van Calker, M Berger, J Bauer, P J Gebicke-Haerte. Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2a-receptors. Glia. vol 18. issue 2. 1997-03-04. PMID:8913778. |
the results are discussed with respect to neurodegenerative disorders of the cns such as alzheimer's disease, in which activated microglia are critically involved and cox inhibitors may be of therapeutic benefit. |
1997-03-04 |
2023-08-12 |
rat |
| P Eikelenboom, R Veerhui. The role of complement and activated microglia in the pathogenesis of Alzheimer's disease. Neurobiology of aging. vol 17. issue 5. 1997-02-18. PMID:8892339. |
the role of complement and activated microglia in the pathogenesis of alzheimer's disease. |
1997-02-18 |
2023-08-12 |
Not clear |
| C Colton, S Wilt, D Gilbert, O Chernyshev, J Snell, M Dubois-Dalc. Species differences in the generation of reactive oxygen species by microglia. Molecular and chemical neuropathology. vol 28. issue 1-3. 1997-01-23. PMID:8871937. |
in order to understand how microglia contribute to changes in oxidative status of the cns and how this might related to disease states, such as alzheimer disease (ad), we have examined the regulation of superoxide anion and nitric oxide production from rodent and human microglia. |
1997-01-23 |
2023-08-12 |
mouse |
| A McRae, E A Ling, A Wigander, A Dahlströ. Microglial cerebrospinal fluid antibodies. Significance for Alzheimer disease. Molecular and chemical neuropathology. vol 28. issue 1-3. 1997-01-23. PMID:8871946. |
hallmark lesions of alzheimer disease (ad) are filled with reactive immunocompetent microglia, suggesting that immunological aderrations may participate in the pathophysiology of this disorder. |
1997-01-23 |
2023-08-12 |
rat |
| A Matsuo, D G Walker, K Terai, P L McGee. Expression of CD43 in human microglia and its downregulation in Alzheimer's disease. Journal of neuroimmunology. vol 71. issue 1-2. 1997-01-22. PMID:8982106. |
expression of cd43 in human microglia and its downregulation in alzheimer's disease. |
1997-01-22 |
2023-08-12 |
human |
| Y Vodovotz, M S Lucia, K C Flanders, L Chesler, Q W Xie, T W Smith, J Weidner, R Mumford, R Webber, C Nathan, A B Roberts, C F Lippa, M B Spor. Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease. The Journal of experimental medicine. vol 184. issue 4. 1996-12-13. PMID:8879214. |
in alzheimer's disease (ad), affected neurons accumulate beta amyloid protein, components of which can induce mouse microglia to express the high-output isoform of nitric oxide synthase (nos2) in vitro. |
1996-12-13 |
2023-08-12 |
mouse |
| D Giulian, L J Haverkamp, J H Yu, W Karshin, D Tom, J Li, J Kirkpatrick, L M Kuo, A E Rohe. Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 19. 1996-12-06. PMID:8815885. |
specific domains of beta-amyloid from alzheimer plaque elicit neuron killing in human microglia. |
1996-12-06 |
2023-08-12 |
human |
| D Giulian, L J Haverkamp, J H Yu, W Karshin, D Tom, J Li, J Kirkpatrick, L M Kuo, A E Rohe. Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 19. 1996-12-06. PMID:8815885. |
alzheimer's disease (ad) is found to have striking brain inflammation characterized by clusters of reactive microglia that surround senile plaques. |
1996-12-06 |
2023-08-12 |
human |
| L F Lue, L Brachova, D G Walker, J Roger. Characterization of glial cultures from rapid autopsies of Alzheimer's and control patients. Neurobiology of aging. vol 17. issue 3. 1996-12-03. PMID:8725904. |
we have developed isolated and mixed cultures of microglia, astrocytes, and oligodendrocytes from rapid (mean of 2 h 55 min) autopsies of nondemented elderly patients and patients with alzheimer's disease, parkinson's disease, and multiple sclerosis. |
1996-12-03 |
2023-08-12 |
human |
| D M Paresce, R N Ghosh, F R Maxfiel. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron. vol 17. issue 3. 1996-11-01. PMID:8816718. |
microglia are immune system cells associated with alzheimer's disease plaques containing beta-amyloid (a beta). |
1996-11-01 |
2023-08-12 |
Not clear |
| M D Ard, G M Cole, J Wei, A P Mehrle, J D Fratki. Scavenging of Alzheimer's amyloid beta-protein by microglia in culture. Journal of neuroscience research. vol 43. issue 2. 1996-10-30. PMID:8820967. |
scavenging of alzheimer's amyloid beta-protein by microglia in culture. |
1996-10-30 |
2023-08-12 |
human |