| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rik Ossenkoppele, Daniel R Schonhaut, Michael Schöll, Samuel N Lockhart, Nagehan Ayakta, Suzanne L Baker, James P O'Neil, Mustafa Janabi, Andreas Lazaris, Averill Cantwell, Jacob Vogel, Miguel Santos, Zachary A Miller, Brianne M Bettcher, Keith A Vossel, Joel H Kramer, Maria L Gorno-Tempini, Bruce L Miller, William J Jagust, Gil D Rabinovic. Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26962052. |
voxel-wise contrasts against controls (at p < 0.05 family-wise error corrected) showed that (18)f-av1451 and (18)f-fdg patterns in patients with posterior cortical atrophy ('visual variant of alzheimer's disease', n = 7) specifically targeted the clinically affected posterior brain regions, while (11)c-pib bound diffusely throughout the neocortex. |
2017-05-08 |
2023-08-13 |
human |
| A V Avetisyan, A N Samokhin, I Y Alexandrova, R A Zinovkin, R A Simonyan, N V Bobkov. Mitochondrial Dysfunction in Neocortex and Hippocampus of Olfactory Bulbectomized Mice, a Model of Alzheimer's Disease. Biochemistry. Biokhimiia. vol 81. issue 6. 2017-01-11. PMID:27301290. |
mitochondrial dysfunction in neocortex and hippocampus of olfactory bulbectomized mice, a model of alzheimer's disease. |
2017-01-11 |
2023-08-13 |
mouse |
| Jasinda H Lee, Shu Qing Koh, Simone Guadagna, Paul T Francis, Margaret M Esiri, Christopher P Chen, Peter T-H Wong, Gavin S Dawe, Mitchell K P La. Altered relaxin family receptors RXFP1 and RXFP3 in the neocortex of depressed Alzheimer's disease patients. Psychopharmacology. vol 233. issue 4. 2016-09-20. PMID:26542729. |
altered relaxin family receptors rxfp1 and rxfp3 in the neocortex of depressed alzheimer's disease patients. |
2016-09-20 |
2023-08-13 |
human |
| Hanna Bielarczyk, Agnieszka Jankowska-Kulawy, Corinna Höfling, Anna Ronowska, Sylwia Gul-Hinc, Steffen Roßner, Reinhard Schliebs, Tadeusz Pawelczyk, Andrzej Szutowic. AβPP-Transgenic 2576 Mice Mimic Cell Type-Specific Aspects of Acetyl-CoA-Linked Metabolic Deficits in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 48. issue 4. 2016-08-03. PMID:26402099. |
deficits of pyruvate dehydrogenase in the neocortex are common features of alzheimer's disease and other age-related encephalopathies in humans. |
2016-08-03 |
2023-08-13 |
mouse |
| Tiina Laiterä, Mitja I Kurki, Juha-Pekka Pursiheimo, Henrik Zetterberg, Seppo Helisalmi, Tuomas Rauramaa, Irina Alafuzoff, Anne M Remes, Hilkka Soininen, Annakaisa Haapasalo, Juha E Jääskeläinen, Mikko Hiltunen, Ville Leinone. The Expression of Transthyretin and Amyloid-β Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients. Journal of Alzheimer's disease : JAD. vol 48. issue 4. 2016-08-03. PMID:26444765. |
idiopathic normal pressure hydrocephalus (inph) is a dementing condition in which alzheimer's disease (ad)-related amyloid-β (aβ) plaques are frequently observed in the neocortex. |
2016-08-03 |
2023-08-13 |
Not clear |
| Sara Porcellotti, Francesca Fanelli, Anna Fracassi, Sara Sepe, Francesco Cecconi, Cinzia Bernardi, AnnaMaria Cimini, Maria Paola Cerù, Sandra Moren. Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease. Oxidative medicine and cellular longevity. vol 2015. 2016-03-29. PMID:25973140. |
oxidative stress during the progression of β-amyloid pathology in the neocortex of the tg2576 mouse model of alzheimer's disease. |
2016-03-29 |
2023-08-13 |
mouse |
| Jeremy Cosgrove, Jane Elizabeth Alty, Stuart Jamieso. Cognitive impairment in Parkinson's disease. Postgraduate medical journal. vol 91. issue 1074. 2015-12-18. PMID:25814509. |
the major pathological correlate of parkinson's disease dementia is lewy body deposition in the limbic system and neocortex although alzheimer's related pathology is also an important contributor. |
2015-12-18 |
2023-08-13 |
Not clear |
| Mitchell K P Lai, Margaret M Esiri, Michelle G K Ta. Genome-wide profiling of alternative splicing in Alzheimer's disease. Genomics data. vol 2. 2015-10-20. PMID:26484111. |
we have previously reported genome-wide gene alterations in the neocortex of a well-characterized cohort of alzheimer's disease (ad) patients and matched elderly controls using a commercial exon microarray platform [1]. |
2015-10-20 |
2023-08-13 |
human |
| F Clavaguera, J Hench, M Goedert, M Tolna. Invited review: Prion-like transmission and spreading of tau pathology. Neuropathology and applied neurobiology. vol 41. issue 1. 2015-09-15. PMID:25399729. |
in the most prevalent tauopathy, alzheimer's disease, tau pathology progresses in a stereotypical manner with the first lesions appearing in the locus coeruleus and the entorhinal cortex from where they appear to spread to the hippocampus and neocortex. |
2015-09-15 |
2023-08-13 |
Not clear |
| Taya Thomas, Scott Miners, Seth Lov. Post-mortem assessment of hypoperfusion of cerebral cortex in Alzheimer's disease and vascular dementia. Brain : a journal of neurology. vol 138. issue Pt 4. 2015-06-16. PMID:25688080. |
perfusion is reduced in the cerebral neocortex in alzheimer's disease. |
2015-06-16 |
2023-08-13 |
Not clear |
| Adriana Ferreir. Calpain dysregulation in Alzheimer's disease. ISRN biochemistry. vol 2012. 2015-05-13. PMID:25969760. |
alzheimer's disease (ad) is characterized by the presence of senile plaques and neurofibrillary tangles in the neocortex and hippocampus of ad patients. |
2015-05-13 |
2023-08-13 |
Not clear |
| E Orta-Salazar, A Aguilar-Vázquez, H Martínez-Coria, S Luquín-De Anda, M Rivera-Cervantes, C Beas-Zarate, A Feria-Velasco, S Díaz-Cintr. REST/NRSF-induced changes of ChAT protein expression in the neocortex and hippocampus of the 3xTg-AD mouse model for Alzheimer's disease. Life sciences. vol 116. issue 2. 2015-01-28. PMID:25261598. |
rest/nrsf-induced changes of chat protein expression in the neocortex and hippocampus of the 3xtg-ad mouse model for alzheimer's disease. |
2015-01-28 |
2023-08-13 |
mouse |
| Sravani Musunuri, Magnus Wetterhall, Martin Ingelsson, Lars Lannfelt, Konstantin Artemenko, Jonas Bergquist, Kim Kultima, Ganna Shevchenk. Quantification of the brain proteome in Alzheimer's disease using multiplexed mass spectrometry. Journal of proteome research. vol 13. issue 4. 2014-12-08. PMID:24606058. |
we have compared the brain proteome in the temporal neocortex between alzheimer's disease (ad) patients and non-ad individuals by using shotgun mass spectrometry based on a stable isotope dimethyl labeling. |
2014-12-08 |
2023-08-12 |
human |
| Christian Grosser, Lisa Neumann, Bernhard Horsthemke, Michael Zeschnigk, Johannes van de Ne. Methylation analysis of SST and SSTR4 promoters in the neocortex of Alzheimer's disease patients. Neuroscience letters. vol 566. 2014-11-11. PMID:24602981. |
methylation analysis of sst and sstr4 promoters in the neocortex of alzheimer's disease patients. |
2014-11-11 |
2023-08-12 |
Not clear |
| Michelle G K Tan, Chingli Lee, Jasinda H Lee, Paul T Francis, Robert J Williams, María J Ramírez, Christopher P Chen, Peter T-H Wong, Mitchell K P La. Decreased rabphilin 3A immunoreactivity in Alzheimer's disease is associated with Aβ burden. Neurochemistry international. vol 64. 2014-10-06. PMID:24200817. |
synaptic dysfunction, together with neuritic plaques, neurofibrillary tangles and cholinergic neuron loss is an established finding in the alzheimer's disease (ad) neocortex. |
2014-10-06 |
2023-08-12 |
Not clear |
| Markus P Kummer, Thea Hammerschmidt, Ana Martinez, Dick Terwel, Gregor Eichele, Anika Witten, Stefanie Figura, Monika Stoll, Stephanie Schwartz, Hans-Christian Pape, Joachim L Schultze, David Weinshenker, Michael T Heneka, Inga Urba. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 26. 2014-08-21. PMID:24966384. |
to assess the consequences of locus ceruleus (lc) degeneration and subsequent noradrenaline (na) deficiency in early alzheimer's disease (ad), mice overexpressing mutant amyloid precursor protein and presenilin-1 (app/ps1) were crossed with ear2(-/-) mice that have a severe loss of lc neurons projecting to the hippocampus and neocortex. |
2014-08-21 |
2023-08-13 |
mouse |
| Faiyaz Ahmed, Raza Murad Ghalib, P Sasikala, K K Mueen Ahme. Cholinesterase inhibitors from botanicals. Pharmacognosy reviews. vol 7. issue 14. 2014-06-24. PMID:24347920. |
alzheimer's disease (ad) is a progressive neurodegenerative disease, wherein a progressive loss of cholinergic synapses occurs in hippocampus and neocortex. |
2014-06-24 |
2023-08-12 |
Not clear |
| Sylvia E Perez, Mary Ann Raghanti, Patrick R Hof, Lynn Kramer, Milos D Ikonomovic, Pascale N Lacor, Joseph M Erwin, Chet C Sherwood, Elliott J Mufso. Alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (Gorilla gorilla gorilla). The Journal of comparative neurology. vol 521. issue 18. 2014-06-11. PMID:23881733. |
alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (gorilla gorilla gorilla). |
2014-06-11 |
2023-08-12 |
Not clear |
| M Morawski, K Nuytens, T Juhasz, U Zeitschel, G Seeger, E Waelkens, L Regal, I Schulz, T Arendt, Z Szeltner, J Creemers, S Rossne. Cellular and ultra structural evidence for cytoskeletal localization of prolyl endopeptidase-like protein in neurons. Neuroscience. vol 242. 2014-05-16. PMID:23485813. |
this staining was reduced in the neocortex of alzheimer's disease (ad) patients. |
2014-05-16 |
2023-08-12 |
mouse |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
alzheimer's disease (ad) is an irreversible neurodegenerative disease that is characterised by the presence of β-amyloid (aβ) plaques, neurofibrillary tangles (nfts) and synaptic loss specifically in brain regions involved in learning and memory such as the neocortex and the hippocampus. |
2014-05-15 |
2023-08-12 |
mouse |