| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Salehi, P J Lucassen, C W Pool, N K Gonatas, R Ravid, D F Swaa. Decreased neuronal activity in the nucleus basalis of Meynert in Alzheimer's disease as suggested by the size of the Golgi apparatus. Neuroscience. vol 59. issue 4. 1994-09-12. PMID:8058125. |
furthermore, these data support the idea that atrophy and decreased activity are the main phenomena in the nucleus basalis in alzheimer's disease; they also indicate that the size of the golgi apparatus is a sensitive parameter to follow this process. |
1994-09-12 |
2023-08-12 |
Not clear |
| W Samuel, R D Terry, R DeTeresa, N Butters, E Maslia. Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia. Archives of neurology. vol 51. issue 8. 1994-08-24. PMID:8042925. |
clinical correlates of cortical and nucleus basalis pathology in alzheimer dementia. |
1994-08-24 |
2023-08-12 |
Not clear |
| H Förstl, R Levy, A Burns, P Luthert, N Cairn. Disproportionate loss of noradrenergic and cholinergic neurons as cause of depression in Alzheimer's disease--a hypothesis. Pharmacopsychiatry. vol 27. issue 1. 1994-05-19. PMID:8159776. |
forty-two patients with neuropathologically confirmed alzheimer's disease, who had been examined prospectively, had a significant decrease of neuron numbers in the locus coeruleus, substantia nigra, and basal nucleus of meynert compared to 10 age-matched, non-demented controls. |
1994-05-19 |
2023-08-12 |
Not clear |
| J L Muir, B J Everitt, T W Robbin. AMPA-induced excitotoxic lesions of the basal forebrain: a significant role for the cortical cholinergic system in attentional function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 4. 1994-05-17. PMID:7512637. |
taken together with our earlier work, which has failed to demonstrate mnemonic deficits following lesions to the magnocellular neurons of the nucleus basalis of meynert, these results suggest that the most consistent deficit produced following lesions of the bf-cortical cholinergic system is attentional dysfunction analogous deficits in visual attention are also seen in patients with alzheimer's disease, which can also be improved by anti-cholinesterase treatment. |
1994-05-17 |
2023-08-12 |
Not clear |
| J L Muir, K J Page, D J Sirinathsinghji, T W Robbins, B J Everit. Excitotoxic lesions of basal forebrain cholinergic neurons: effects on learning, memory and attention. Behavioural brain research. vol 57. issue 2. 1994-04-06. PMID:7509608. |
a substantial body of literature has suggested that the memory and learning deficits associated with alzheimer's disease are attributable to degeneration of the cholinergic magnocellular neurons of the nucleus basalis of meynert (nbm). |
1994-04-06 |
2023-08-12 |
Not clear |
| K Kyoshima, M Matsuda, J Hand. [Transplantation of basal forebrain cells of fetal rats into the subarachnoid space: improvement of disturbance of passive avoidance memory due to injury of basal forebrain]. Nihon geka hokan. Archiv fur japanische Chirurgie. vol 62. issue 4. 1994-03-11. PMID:8311641. |
the memory disturbance of senile dementia of alzheimer type has been thought to associate with marked degeneration and loss of cholinergic neurons of the basal forebrain (nucleus basalis of meynert, nbm). |
1994-03-11 |
2023-08-12 |
rat |
| A Donne. [The basal forebrain. Neuroanato-physiology and neurologic applications]. L'Encephale. vol 19. issue 3. 1994-02-07. PMID:8275909. |
neurons of the nucleus basalis of meynert undergo a profound degeneration in patients with alzheimer's disease and provide a pathological substrate of the cholinergic deficiency in their brain. |
1994-02-07 |
2023-08-12 |
Not clear |
| E J Mufson, E Cochran, W Benzing, J H Kordowe. Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging, Alzheimer's disease and Down's syndrome. Dementia (Basel, Switzerland). vol 4. issue 5. 1994-01-27. PMID:7505157. |
the galanin (gal) containing peptide fiber system circuit which innervates acetylcholine containing basal forebrain neurons has been shown to hypertrophy and hyperinnervate remaining cholinergic ch4 perikarya in alzheimer's disease (ad). |
1994-01-27 |
2023-08-12 |
Not clear |
| V Chan-Palay, M Höchli, E Savaskan, G Hungerecke. Calbindin D-28k and monoamine oxidase A immunoreactive neurons in the nucleus basalis of Meynert in senile dementia of the Alzheimer type and Parkinson's disease. Dementia (Basel, Switzerland). vol 4. issue 1. 1993-09-30. PMID:8358501. |
calbindin d-28k and monoamine oxidase a immunoreactive neurons in the nucleus basalis of meynert in senile dementia of the alzheimer type and parkinson's disease. |
1993-09-30 |
2023-08-12 |
Not clear |
| V Chan-Palay, M Höchli, E Savaskan, G Hungerecke. Calbindin D-28k and monoamine oxidase A immunoreactive neurons in the nucleus basalis of Meynert in senile dementia of the Alzheimer type and Parkinson's disease. Dementia (Basel, Switzerland). vol 4. issue 1. 1993-09-30. PMID:8358501. |
in this study, calbindin d-28k (cabp), monoamine oxidase a (mao a) and nerve growth factor receptor (ngfr) immunoreactivities were investigated in the nucleus basalis of meynert (nbm) in patients with senile dementia of the alzheimer type (sdat), with parkinson's disease (pd) with or without dementia, and in controls. |
1993-09-30 |
2023-08-12 |
Not clear |
| M Takahashi, K Sugaya, K Kojima, T Katoh, M Ueki, K Kubot. SUT-8701, a cholecystokinin analog, prevents the cholinergic degeneration in the rat cerebral cortex following basal forebrain lesioning. Japanese journal of pharmacology. vol 61. issue 4. 1993-08-03. PMID:8320879. |
these results suggest that sut-8701 may be effective in slowing down the degenerative processes in alzheimer's disease by preserving the integrity of cholinergic neurons in the nucleus basalis. |
1993-08-03 |
2023-08-12 |
mouse |
| I Kracun, S Kalanj, J Talan-Hranilovic, C Cosovi. Cortical distribution of gangliosides in Alzheimer's disease. Neurochemistry international. vol 20. issue 3. 1993-07-02. PMID:1304338. |
in alzheimer's disease, all ganglio-series gangliosides (gm1, gd1a, gd1b and gt1b) were found to be decreased in temporal and frontal cortex, and nucleus basalis of meynert. |
1993-07-02 |
2023-08-11 |
Not clear |
| E Moyse, E Szigethy, J M Danger, H Vaudry, G L Wenk, A Beaudet, J Epelbau. Short- and long-term effects of nucleus basalis magnocellularis lesions on cortical levels of somatostatin and its receptors in the rat. Brain research. vol 607. issue 1-2. 1993-06-03. PMID:8097661. |
cognitive and histological alterations in human alzheimer's disease (ad) are correlated with selective neuronal loss in nucleus basalis of meynert. |
1993-06-03 |
2023-08-12 |
human |
| T Arendt, M K Brückne. Perisomatic sprouts immunoreactive for nerve growth factor receptor and neurofibrillary degeneration affect different neuronal populations in the basal nucleus in patients with Alzheimer's disease. Neuroscience letters. vol 148. issue 1-2. 1993-05-26. PMID:1300505. |
perisomatic sprouts immunoreactive for nerve growth factor receptor and neurofibrillary degeneration affect different neuronal populations in the basal nucleus in patients with alzheimer's disease. |
1993-05-26 |
2023-08-11 |
mouse |
| T Arendt, M K Brückne. Perisomatic sprouts immunoreactive for nerve growth factor receptor and neurofibrillary degeneration affect different neuronal populations in the basal nucleus in patients with Alzheimer's disease. Neuroscience letters. vol 148. issue 1-2. 1993-05-26. PMID:1300505. |
aberrant morphological profiles, most likely reflecting a process of perisomatic sprouting, have been detected in alzheimer's disease (ad) on neurons of the basal nucleus of meynert by means of golgi impregnation. |
1993-05-26 |
2023-08-11 |
mouse |
| S Lehéricy, E C Hirsch, P Cervera-Piérot, L B Hersh, S Bakchine, F Piette, C Duyckaerts, J J Hauw, F Javoy-Agid, Y Agi. Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease. The Journal of comparative neurology. vol 330. issue 1. 1993-05-11. PMID:8468401. |
cholinergic neurons were studied by immunohistochemistry, with an antiserum against choline acetyltransferase (chat), in the basal forebrain (ch1 to ch4) of four patients with alzheimer's disease (ad) and four control subjects. |
1993-05-11 |
2023-08-12 |
human |
| M Takahashi, K Sugaya, K Kubot. Kangenkaryu prevents the decrease of cholinergic markers following the nucleus basalis magnocellularis lesion. Japanese journal of pharmacology. vol 60. issue 3. 1993-03-02. PMID:1491519. |
the nucleus basalis magnocellularis (nbm)-lesioned rat is considered to be a model of the cholinergic dysfunction observed in the cerebral cortices of alzheimer's disease patients. |
1993-03-02 |
2023-08-11 |
rat |
| E De Micheli, T T Soncran. Age-dependent cerebral metabolic effects of unilateral nucleus basalis magnocellularis ablation in rats. Neurobiology of aging. vol 13. issue 6. 1993-02-26. PMID:1491734. |
to investigate the age-dependent functional importance of cholinergic neocortical inputs, and to explore whether cortical cholinergic denervation in aged animals might better model the cerebral metabolic changes of alzheimer's disease, the effects of unilateral ablation of the nucleus basalis magnocellularis (nbm) on cerebral glucose metabolism were studied in young and aged rats. |
1993-02-26 |
2023-08-11 |
rat |
| K Kosak. Dementia and neuropathology in Lewy body disease. Advances in neurology. vol 60. 1993-02-11. PMID:8420170. |
in some of the cases with the brain-stem type of lewy body disease, the dementia was attributed to an alzheimer pathology, while in many cases the various combinations of degeneration in the subcortical nuclei, mainly the nucleus basalis of meynert and locus ceruleus, played a major role in the dementia. |
1993-02-11 |
2023-08-12 |
Not clear |
| J K Robinson, J N Crawle. The role of galanin in cholinergically-mediated memory processes. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 1. 1993-01-21. PMID:7677976. |
galanin coexists with acetylcholine in neurons of the medial septum, diagonal band, and nucleus basalis of meynert, cells which degenerate during the course of alzheimer's disease. |
1993-01-21 |
2023-08-12 |
rat |