| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Siyu Bao, Tianjie Li, Xiaoyu Long, Jinjuan Zhang, Hongcui Zhao, Yun Ren, Yue Zhao, Rong Li, Tao Tan, Yang Yu, Jie Qia. Chemokine Receptor Type 4 Regulates Migration and Invasion of Trophectoderm Cell in the Human Blastocyst. Biology of reproduction. vol 95. issue 1. 2017-10-24. PMID:27146031. |
bioinformatic analysis indicated that cxcr4 can induce cell apoptosis and migration mediated by rho signaling. |
2017-10-24 |
2023-08-13 |
mouse |
| Qianqian Zheng, Shigang Li, Yunli Jia, Wei Liu, Lingling Yu, Xianyong Chen, Jinling Wan. [Tryptase inhibits cell apoptosis through upregulating PAR-2 and Rho kinase in rheumatoid arthritis synovial fibroblasts]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 12. 2017-06-13. PMID:27916091. |
[tryptase inhibits cell apoptosis through upregulating par-2 and rho kinase in rheumatoid arthritis synovial fibroblasts]. |
2017-06-13 |
2023-08-13 |
Not clear |
| Qianqian Zheng, Shigang Li, Yunli Jia, Wei Liu, Lingling Yu, Xianyong Chen, Jinling Wan. [Tryptase inhibits cell apoptosis through upregulating PAR-2 and Rho kinase in rheumatoid arthritis synovial fibroblasts]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 12. 2017-06-13. PMID:27916091. |
objective to investigate the regulatory effects of tryptase on protease-activated receptors 2 (par-2), rho signal pathway and apoptosis of mh7a rheumatoid arthritis synovial fibroblasts. |
2017-06-13 |
2023-08-13 |
Not clear |
| Qianqian Zheng, Shigang Li, Yunli Jia, Wei Liu, Lingling Yu, Xianyong Chen, Jinling Wan. [Tryptase inhibits cell apoptosis through upregulating PAR-2 and Rho kinase in rheumatoid arthritis synovial fibroblasts]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 12. 2017-06-13. PMID:27916091. |
methods in mh7a cells, the expression of par-2 was measured by flow cytometry; cell apoptosis was examined by annexin v- fitc/pi staining combined with flow cytometry; the expression of rho kinase was detected by pull-down assay and western botting. |
2017-06-13 |
2023-08-13 |
Not clear |
| Qianqian Zheng, Shigang Li, Yunli Jia, Wei Liu, Lingling Yu, Xianyong Chen, Jinling Wan. [Tryptase inhibits cell apoptosis through upregulating PAR-2 and Rho kinase in rheumatoid arthritis synovial fibroblasts]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 12. 2017-06-13. PMID:27916091. |
conclusion tryptase plays a role in resistance to the apoptosis of mh7a cells through raising par-2 and activating rho kinase. |
2017-06-13 |
2023-08-13 |
Not clear |
| Shuyi Chen, Chunli Sun, Huawei Gu, Haiying Wang, Shan Li, Yi Ma, Jufang Wan. Salubrinal protects against Clostridium difficile toxin B-induced CT26 cell death. Acta biochimica et biophysica Sinica. vol 49. issue 3. 2017-06-01. PMID:28119311. |
two exotoxins of c. difficile, toxin a (tcda) and toxin b (tcdb), are the main virulence factors of cdi, which can induce glucosylation of rho gtpases in host cytosol, leading to cell morphological changes, cell apoptosis, and cell death. |
2017-06-01 |
2023-08-13 |
mouse |
| Yi-Xiang Liao, Jin-Min Zeng, Jia-Jie Zhou, Guang-Hua Yang, Kun Ding, Xian-Jue Zhan. Silencing of RTKN2 by siRNA suppresses proliferation, and induces G1 arrest and apoptosis in human bladder cancer cells. Molecular medicine reports. vol 13. issue 6. 2017-04-06. PMID:27082503. |
therefore, the present study investigated the expression levels of rhotekin 2 (rtkn2), a rho effector protein, in human bladder cancer tissues and cell lines, and examined the effect of rtkn2 on the proliferation, cell cycle, apoptosis and invasion of human bladder cancer cell lines. |
2017-04-06 |
2023-08-13 |
human |
| Christina Niermann, Simone Gorressen, Meike Klier, Nina S Gowert, Pierre Billuart, Malte Kelm, Marc W Merx, Margitta Elver. Oligophrenin1 protects mice against myocardial ischemia and reperfusion injury by modulating inflammation and myocardial apoptosis. Cellular signalling. vol 28. issue 8. 2017-02-22. PMID:27117132. |
loss of ophn1 induced enhanced activity of rho effector molecules leading to elevated cardiomyocyte apoptosis and increased migration of inflammatory cells into the infarct border zone of ophn1 deficient mice. |
2017-02-22 |
2023-08-13 |
mouse |
| Hamidreza Edrissi, Sarah C Schock, Antoine M Hakim, Charlie S Thompso. Microparticles generated during chronic cerebral ischemia increase the permeability of microvascular endothelial barriers in vitro. Brain research. vol 1634. 2016-12-13. PMID:26723565. |
we conclude that the increase in permeability of artificial barriers induced by mps is primarily due to enhanced apoptosis induced by activation of the tnf-α pathway and activated caspase 3 and rho kinases delivered to endothelial cells by mps. |
2016-12-13 |
2023-08-13 |
rat |
| Jinjuan Zhang, Tianjie Li, Weizhi Ji, Yang Yu, Tao Ta. Rho GDIalpha Modulates Rabbit Trophoblast Stem Cell Survival and Migration. Biology of reproduction. vol 93. issue 6. 2016-10-05. PMID:26559677. |
here we report that overexpression of rho gdialpha resulted in rapid apoptosis of tscs, while its knockdown promoted proliferation. |
2016-10-05 |
2023-08-13 |
rabbit |
| Liang Wu, Xinye Han, Yuan Liu, Danhua Su, Tao Fu, Xugan Jiang, Shengxia Chen, Huaxi X. [Increased apoptosis and down-regulation of RhoA in HepG2 cells infected by Listeria monocytogenes]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 5. 2016-09-22. PMID:27126939. |
to explore the apoptosis of hepg2 cells infected by listeria monocytogenes egd strain (lm-egd) as well as rho family small gtpases rhoa expression. |
2016-09-22 |
2023-08-13 |
Not clear |
| Priscila F de Aquino, Paulo Costa Carvalho, Fábio C S Nogueira, Clovis Orlando da Fonseca, Júlio Cesar Thomé de Souza Silva, Maria da Gloria da Costa Carvalho, Gilberto B Domont, Nilson I T Zanchin, Juliana de Saldanha da Gama Fische. A Time-Based and Intratumoral Proteomic Assessment of a Recurrent Glioblastoma Multiforme. Frontiers in oncology. vol 6. 2016-09-06. PMID:27597932. |
we discuss several key proteins (e.g., s100a9) and enriched pathways linked with gbm such as the ras pathway, rho gtpases activate pkns, and those related to apoptosis, to name a few. |
2016-09-06 |
2023-08-13 |
Not clear |
| Cui-Ping Yin, Shang-Hui Guan, Bo Zhang, Xue-Xin Wang, Shou-Wei Yu. Upregulation of HIF-1α protects neuroblastoma cells from hypoxia-induced apoptosis in a RhoA-dependent manner. Molecular medicine reports. vol 12. issue 5. 2016-08-22. PMID:26323527. |
the ras homolog (rho) family, including rho member a (rhoa), is involved in reorganization of the actin cytoskeleton, cell migration and in the regulation of apoptosis and gene transcription. |
2016-08-22 |
2023-08-13 |
Not clear |
| Hongyi Zhu, Xiangguo Cheng, Xin Niu, Yuelei Zhang, Junjie Guan, Xiaolin Liu, Shicong Tao, Yang Wang, Changqing Zhan. Proton-sensing GPCR-YAP Signalling Promotes Cell Proliferation and Survival. International journal of biological sciences. vol 11. issue 10. 2016-06-27. PMID:26327812. |
furthermore, we demonstrated that proton-sensing g-protein-coupled receptors (gpcrs) are required for the ph-dependent regulation of proliferation and apoptosis through the g protein α subunit 12/13 (g12/13) and rho gtpases. |
2016-06-27 |
2023-08-13 |
Not clear |
| Ting Peng, Wei-Na Wang, Mei-Mei Gu, Chen-Ying Xie, Yu-Chao Xiao, Yuan Liu, Lei Wan. Essential roles of Cdc42 and MAPK in cadmium-induced apoptosis in Litopenaeus vannamei. Aquatic toxicology (Amsterdam, Netherlands). vol 163. 2016-01-11. PMID:25863597. |
the mitogen-activated protein kinase (mapk) signaling pathway plays a vital role in animals' stress responses, including mediation of apoptosis induced by the rho gtpase cdc42. |
2016-01-11 |
2023-08-13 |
Not clear |
| Mihwa Kim, Ahrom Ham, Katelyn Yu-Mi Kim, Kevin M Brown, H Thomas Le. The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release. PloS one. vol 9. issue 6. 2015-10-19. PMID:24945528. |
taken together, we conclude that the volatile anesthetic isoflurane causes rho kinase-mediated release of endothelial microparticles containing preformed cd73 and increase adenosine generation to protect against endothelial apoptosis and inflammation. |
2015-10-19 |
2023-08-13 |
mouse |
| Ambrish Kumar, Nadia Al-Sammarraie, Donald J DiPette, Ugra S Sing. Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma. Oncotarget. vol 5. issue 22. 2015-09-24. PMID:25365944. |
metformin impairs rho gtpase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma. |
2015-09-24 |
2023-08-13 |
mouse |
| Ambrish Kumar, Nadia Al-Sammarraie, Donald J DiPette, Ugra S Sing. Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma. Oncotarget. vol 5. issue 22. 2015-09-24. PMID:25365944. |
these studies demonstrated that metformin impairs rho gtpases signaling to induce apoptosis via jnk pathway. |
2015-09-24 |
2023-08-13 |
mouse |
| Jose J G Marin, Alicia Hernandez, Isabel E Revuelta, Ester Gonzalez-Sanchez, Jose M Gonzalez-Buitrago, Maria J Pere. Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: role of the Akt/mTOR survival pathway and Bcl-2 family proteins. Free radical biology & medicine. vol 61. 2015-08-21. PMID:23597504. |
in the absence of changes in intracellular atp content, rho cells were highly resistant to bile acid-induced apoptosis and partially resistant to bile acid-induced necrosis. |
2015-08-21 |
2023-08-12 |
human |
| Xiao Liu, Zhengzheng Zhang, Xianliang Yan, He Liu, Licai Zhang, Aiming Yao, Chengcheng Guo, Xiaoyun Liu, Tie X. The Rho kinase inhibitor Y-27632 facilitates the differentiation of bone marrow mesenchymal stem cells. Journal of molecular histology. vol 45. issue 6. 2015-07-15. PMID:25178638. |
the rho gtpases and downstream rho kinases (rho coiled-coil kinases or rocks) are central regulators of cytoskeletal dynamics during the cell cycle and thus help determine the balance between stem cells self-renewal, lineage commitment, and apoptosis. |
2015-07-15 |
2023-08-13 |
Not clear |