| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Subrata K Bose, Mitul A Mehta, Sudhakar Selvaraj, Oliver D Howes, Rainer Hinz, Eugenii A Rabiner, Paul M Grasby, Federico E Turkheimer, Venkatesha Murth. Presynaptic 5-HT1A is related to 5-HTT receptor density in the human brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 11. 2012-03-20. PMID:21750580. |
we hypothesized that lower 5-htt densities in the dorsal raphe nucleus (drn) and limbic regions will be accompanied by lower 5-ht1a receptor density in the same regions, contributing to the 5-ht1a receptor desensitization. |
2012-03-20 |
2023-08-12 |
human |
| Cynthia L Bethea, Fernanda B Lima, Maria L Centeno, Karin V Weissheimer, Olga Senashova, Arubala P Reddy, Judy L Camero. Effects of citalopram on serotonin and CRF systems in the midbrain of primates with differences in stress sensitivity. Journal of chemical neuroanatomy. vol 41. issue 4. 2012-02-22. PMID:21683135. |
examination of the serotonin system revealed that ss monkeys had significantly lower fev (fifth ewing variant, rodent pet1), tph2 (tryptophan hydroxylase 2), 5ht1a autoreceptor and sert (serotonin reuptake transporter) expression in the dorsal raphe than sr monkeys. |
2012-02-22 |
2023-08-12 |
monkey |
| L B Gualda, G G Martins, B Müller, F S Guimarães, R M W Oliveir. 5-HT1A autoreceptor modulation of locomotor activity induced by nitric oxide in the rat dorsal raphe nucleus. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 44. issue 4. 2012-02-09. PMID:21445531. |
5-ht1a autoreceptor modulation of locomotor activity induced by nitric oxide in the rat dorsal raphe nucleus. |
2012-02-09 |
2023-08-12 |
rat |
| Su-Ying Cui, Xiang-Yu Cui, Juan Zhang, Zi-Jun Wang, Bin Yu, Zhao-Fu Sheng, Xue-Qiong Zhang, Xiao-Lei Shi, Yong-He Zhan. Diltiazem potentiates pentobarbital-induced hypnosis via 5-HT1A and 5-HT2A/2C receptors: role for dorsal raphe nucleus. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21689675. |
diltiazem potentiates pentobarbital-induced hypnosis via 5-ht1a and 5-ht2a/2c receptors: role for dorsal raphe nucleus. |
2011-12-09 |
2023-08-12 |
rat |
| Christian Beste, Katharina Domschke, Britta Radenz, Michael Falkenstein, Carsten Konra. The functional 5-HT1A receptor polymorphism affects response inhibition processes in a context-dependent manner. Neuropsychologia. vol 49. issue 9. 2011-12-06. PMID:21645534. |
as the functional effect of the 5-ht1a c(-1019)g polymorphism has previously been shown to be rather specific for serotonergic 1a autoreceptors in the dorsal raphe nucleus (drn), the results suggest that contextual modulations in cognitive control may be exerted by the drn. |
2011-12-06 |
2023-08-12 |
human |
| Tamara B Franklin, Natacha Linder, Holger Russig, Beat Thöny, Isabelle M Mansu. Influence of early stress on social abilities and serotonergic functions across generations in mice. PloS one. vol 6. issue 7. 2011-12-06. PMID:21799751. |
the defects are associated with impaired serotonergic signaling, in particular, reduced 5ht1a receptor expression in the dorsal raphe nucleus, and increased serotonin level in a dorsal raphe projection area. |
2011-12-06 |
2023-08-12 |
mouse |
| Robert R Rozeske, Andrew K Evans, Matthew G Frank, Linda R Watkins, Christopher A Lowry, Steven F Maie. Uncontrollable, but not controllable, stress desensitizes 5-HT1A receptors in the dorsal raphe nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 40. 2011-11-18. PMID:21976495. |
uncontrollable, but not controllable, stress desensitizes 5-ht1a receptors in the dorsal raphe nucleus. |
2011-11-18 |
2023-08-12 |
rat |
| Fei-Fei Luo, Fang Han, Yu-Xiu Sh. Changes in 5-HT1A receptor in the dorsal raphe nucleus in a rat model of post-traumatic stress disorder. Molecular medicine reports. vol 4. issue 5. 2011-11-01. PMID:21720713. |
changes in 5-ht1a receptor in the dorsal raphe nucleus in a rat model of post-traumatic stress disorder. |
2011-11-01 |
2023-08-12 |
rat |
| Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. |
shifting topographic activation and 5-ht1a receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. |
2011-09-26 |
2023-08-12 |
Not clear |
| L Y Yeung, H F Kung, David T Ye. Localization of 5-HT1A and 5-HT2A positive cells in the brainstems of control age-matched and Alzheimer individuals. Age (Dordrecht, Netherlands). vol 32. issue 4. 2011-04-04. PMID:20508993. |
the 5-ht1a positive cells were found in substantia nigra, pontile nucleus, and vagal as well as dorsal raphe nucleus, while 5-ht2a receptor positive cells were found in motor, sensory and spinal trigeminal nuclei, pontile nucleus, substantia nigra, and nucleus solitarius. |
2011-04-04 |
2023-08-12 |
human |
| L Y Yeung, H F Kung, David T Ye. Localization of 5-HT1A and 5-HT2A positive cells in the brainstems of control age-matched and Alzheimer individuals. Age (Dordrecht, Netherlands). vol 32. issue 4. 2011-04-04. PMID:20508993. |
statistically significant differences (p ≤ 0.01) in density were observed in 5-ht1a cells in pontile, dorsal raphe, and vagal nuclei between control age-matched and alzheimer, and in 5-ht2a positive cells in the sensory trigeminal nucleus, between control and alzheimer. |
2011-04-04 |
2023-08-12 |
human |
| Elsa Maria Valdizán, Elena Castro, Angel Pazo. Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus. The international journal of neuropsychopharmacology. vol 13. issue 7. 2011-01-10. PMID:19895724. |
agonist-dependent modulation of g-protein coupling and transduction of 5-ht1a receptors in rat dorsal raphe nucleus. |
2011-01-10 |
2023-08-12 |
rat |
| Elsa Maria Valdizán, Elena Castro, Angel Pazo. Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus. The international journal of neuropsychopharmacology. vol 13. issue 7. 2011-01-10. PMID:19895724. |
in order to evaluate the possible existence of agonist-directed trafficking for 5-ht1a autoreceptors in the rat dorsal raphe nucleus, we studied their activation by two agonists with a different profile of efficacy [(+)8-oh-dpat and buspirone], addressing simultaneously the identification of the specific galpha subtypes ([35s]gtpgammas labelling and immunoprecipitation) involved and the subsequent changes in camp formation. |
2011-01-10 |
2023-08-12 |
rat |
| Andreas Hahn, Rupert Lanzenberger, Wolfgang Wadsak, Christoph Spindelegger, Uirike Moser, Leonhard-Key Mien, Markus Mitterhauser, Siegfried Kaspe. Escitalopram enhances the association of serotonin-1A autoreceptors to heteroreceptors in anxiety disorders. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 43. 2010-11-30. PMID:20980606. |
the 5-ht1a receptor binding potential (bpnd) was quantified for the dorsal raphe nucleus (drn) using a region-of-interest approach and for the entire brain by calculating parametric maps. |
2010-11-30 |
2023-08-12 |
human |
| Mohammad Charkhpour, Ali Reza Mohajjel Nayebi, Yousef Doustar, Kambiz Hassanzade. 8-OH-DPAT prevents morphine-induced apoptosis in rat dorsal raphe nucleus: a possible mechanism for attenuating morphine tolerance. Anesthesia and analgesia. vol 111. issue 5. 2010-11-16. PMID:20736434. |
previously, we found that activation of serotonin 1a (5-ht1a) receptors in the dorsal raphe nucleus (drn) decreased the development of tolerance to the analgesic effect of morphine. |
2010-11-16 |
2023-08-12 |
rat |
| Eugene Oh, Takashi Maejima, Chen Liu, Evan Deneris, Stefan Herlitz. Substitution of 5-HT1A receptor signaling by a light-activated G protein-coupled receptor. The Journal of biological chemistry. vol 285. issue 40. 2010-10-26. PMID:20643652. |
finally, rh-ct(5-ht1a) is able to rescue 5-ht(1a) signaling of 5-ht(1a) ko mice in cultured neurons and in slices of the dorsal raphe showing that rh-ct(5-ht1a) is able to functionally compensate for native 5-ht(1a). |
2010-10-26 |
2023-08-12 |
mouse |
| Christian Beste, Katharina Domschke, Michael Falkenstein, Carsten Konra. Differential modulations of response control processes by 5-HT1A gene variation. NeuroImage. vol 50. issue 2. 2010-05-11. PMID:19962444. |
the functional effect of the 5-ht1a c(-1019)g polymorphism has previously been shown to be specific for serotonergic 1 a autoreceptors of serotonergic neurons in the dorsal raphe nucleus (drn). |
2010-05-11 |
2023-08-12 |
Not clear |
| F B Lima, M L Centeno, M E Costa, A P Reddy, J L Cameron, C L Bethe. Stress sensitive female macaques have decreased fifth Ewing variant (Fev) and serotonin-related gene expression that is not reversed by citalopram. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19671441. |
fev (fifth ewing variant) ets transcription factor, tryptophan hydroxylase 2 (tph2), the serotonin reuptake transporter (sert), and the 5ht1a autoreceptor were determined at 7-8 levels of the dorsal raphe nucleus with in situ hybridization (ish) using radiolabeled- and digoxygenin-incorporated riboprobes. |
2010-02-12 |
2023-08-12 |
monkey |
| F B Lima, M L Centeno, M E Costa, A P Reddy, J L Cameron, C L Bethe. Stress sensitive female macaques have decreased fifth Ewing variant (Fev) and serotonin-related gene expression that is not reversed by citalopram. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19671441. |
ss monkeys also had significantly lower levels of tph2, sert and 5ht1a mrnas in the dorsal raphe nucleus than hsr monkeys. |
2010-02-12 |
2023-08-12 |
monkey |
| N A Urtikova, A Ia Sapronova, M J Brisorgueil, D Verge, M V Ugriumo. [Development of serotonergic neurons of dorsal raphe nuclei in mice with knockout of monoamine oxidase A and 5-HT1A and 5-HT1B autoreceptor]. Ontogenez. vol 40. issue 4. 2009-10-02. PMID:19705758. |
[development of serotonergic neurons of dorsal raphe nuclei in mice with knockout of monoamine oxidase a and 5-ht1a and 5-ht1b autoreceptor]. |
2009-10-02 |
2023-08-12 |
mouse |