| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Analía Bortolozzi, Mercè Amargós-Bosch, Miklos Toth, Francesc Artigas, Albert Adel. In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of neurochemistry. vol 88. issue 6. 2004-04-15. PMID:15009637. |
in vivo efflux of serotonin in the dorsal raphe nucleus of 5-ht1a receptor knockout mice. |
2004-04-15 |
2023-08-12 |
mouse |
| Analía Bortolozzi, Mercè Amargós-Bosch, Miklos Toth, Francesc Artigas, Albert Adel. In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of neurochemistry. vol 88. issue 6. 2004-04-15. PMID:15009637. |
in the dorsal raphe nucleus (dr), extracellular serotonin (5-ht) regulates serotonergic transmission through 5-ht1a autoreceptors. |
2004-04-15 |
2023-08-12 |
mouse |
| G Fairchild, M M Leitch, C D Ingra. Acute and chronic effects of corticosterone on 5-HT1A receptor-mediated autoinhibition in the rat dorsal raphe nucleus. Neuropharmacology. vol 45. issue 7. 2003-12-29. PMID:14573385. |
acute and chronic effects of corticosterone on 5-ht1a receptor-mediated autoinhibition in the rat dorsal raphe nucleus. |
2003-12-29 |
2023-08-12 |
rat |
| Petrus J Pauwels, Francis C Colpaer. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. The Journal of pharmacology and experimental therapeutics. vol 307. issue 2. 2003-12-10. PMID:12970382. |
little experimental evidence has been reported for diverse signaling via 5-hydroxytryptamine (5-ht)1a receptors despite the fact that agonists seem to be more efficacious at dorsal raphe somatodendritic 5-ht1a autoreceptors than at postsynaptic 5-ht1a receptors. |
2003-12-10 |
2023-08-12 |
human |
| Bea J van der Vegt, Natasja Lieuwes, Esther H E M van de Wall, Katsunori Kato, Luis Moya-Albiol, Sonia Martínez-Sanchis, Sietse F de Boer, Jaap M Koolhaa. Activation of serotonergic neurotransmission during the performance of aggressive behavior in rats. Behavioral neuroscience. vol 117. issue 4. 2003-09-09. PMID:12931952. |
to test this hypothesis, first, the 5-ht1a agonist alnespirone and gamma aminobutyric acid-a agonist muscimol were administered into the dorsal raphe nucleus. |
2003-09-09 |
2023-08-12 |
rat |
| Yoko Hagino, Masayuki Watanab. Effects of clozapine on the efflux of serotonin and dopamine in the rat brain: the role of 5-HT1A receptors. Canadian journal of physiology and pharmacology. vol 80. issue 12. 2003-08-13. PMID:12564641. |
this result suggests that the ability of clozapine to enhance the extracellular concentrations of 5-ht in the dorsal raphe attenuates this drug's effect in the frontal cortex, probably through the stimulation of 5-ht1a somatodendritic autoreceptors in the dorsal raphe. |
2003-08-13 |
2023-08-12 |
rat |
| D A Johnson, S E Gartside, C D Ingra. 5-HT1A receptor-mediated autoinhibition does not function at physiological firing rates: evidence from in vitro electrophysiological studies in the rat dorsal raphe nucleus. Neuropharmacology. vol 43. issue 6. 2003-06-24. PMID:12423665. |
5-ht1a receptor-mediated autoinhibition does not function at physiological firing rates: evidence from in vitro electrophysiological studies in the rat dorsal raphe nucleus. |
2003-06-24 |
2023-08-12 |
rat |
| Daisuke Mochizuki, Tadami Hokonohara, Koh Kawasaki, Naomasa Mik. Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors. Journal of psychopharmacology (Oxford, England). vol 16. issue 3. 2003-04-07. PMID:12236634. |
in-vitro electrophysiological recordings in the dorsal raphe nucleus showed that 5-ht inhibited the firing of serotonergic neurones, and the selective 5-ht1a receptor antagonist, n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-(2-pyridinyl) cyclohexane carboxamide (way 100635), reversed the inhibitory effect of 5-ht. |
2003-04-07 |
2023-08-12 |
rat |
| Luca Santarelli, Gabriella Gobbi, Pierre Blier, René He. Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). The Journal of clinical psychiatry. vol 63 Suppl 11. 2003-02-11. PMID:12562138. |
in parallel with these behavioral effects, physiologic changes, such as an increased firing rate of 5-hydroxytryptamine (5-ht) neurons in the dorsal raphe nuclei and a desensitization of presynaptic 5-ht1a inhibitory autoreceptors, were observed. |
2003-02-11 |
2023-08-12 |
mouse |
| R M Craven, D G Grahame-Smith, N R Newberr. 5-HT1A and 5-HT2 receptors differentially regulate the excitability of 5-HT-containing neurones of the guinea pig dorsal raphe nucleus in vitro. Brain research. vol 899. issue 1-2. 2002-04-02. PMID:11311877. |
5-ht1a and 5-ht2 receptors differentially regulate the excitability of 5-ht-containing neurones of the guinea pig dorsal raphe nucleus in vitro. |
2002-04-02 |
2023-08-12 |
rat |
| Maxime Richer, René Hen, Pierre Blie. Modification of serotonin neuron properties in mice lacking 5-HT1A receptors. European journal of pharmacology. vol 435. issue 2-3. 2002-03-27. PMID:11821026. |
using null mutant mice for the 5-ht1a receptor (5-ht1a-/-), extracellular electrophysiological recordings were first conducted to evaluate the impact of its genetic deletion on the firing rate of dorsal raphe 5-hydroxytryptamine (5-ht) neurons. |
2002-03-27 |
2023-08-12 |
mouse |
| H Kats. Selective 5-HT1A receptor agonist, 8-OH-DPAT, locally administered into the dorsal raphe nucleus increased extracellular acetylcholine concentrations in the medial prefrontal cortex of conscious rats. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 21. issue 4. 2002-03-08. PMID:11769569. |
selective 5-ht1a receptor agonist, 8-oh-dpat, locally administered into the dorsal raphe nucleus increased extracellular acetylcholine concentrations in the medial prefrontal cortex of conscious rats. |
2002-03-08 |
2023-08-12 |
rat |
| J M Monti, H Jantos, D Monti, F Alvariñ. Dorsal raphe nucleus administration of 5-HT1A receptor agonist and antagonists: effect on rapid eye movement sleep in the rat. Sleep research online : SRO. vol 3. issue 1. 2001-12-04. PMID:11382897. |
dorsal raphe nucleus administration of 5-ht1a receptor agonist and antagonists: effect on rapid eye movement sleep in the rat. |
2001-12-04 |
2023-08-12 |
rat |
| M He, E Sibille, D Benjamin, M Toth, T Shippenber. Differential effects of 5-HT1A receptor deletion upon basal and fluoxetine-evoked 5-HT concentrations as revealed by in vivo microdialysis. Brain research. vol 902. issue 1. 2001-09-20. PMID:11376590. |
basal and fluoxetine-evoked extracellular concentrations of 5-ht were quantified in the striatum, a projection area of dorsal raphe neurons (drn), of wild-type (wt) and 5-ht1a receptor knock out (ko) mice. |
2001-09-20 |
2023-08-12 |
mouse |
| A Newman-Tancredi, C Chaput, M Touzard, M J Milla. Pindolol antagonises G-protein activation at both pre- and postsynaptic serotonin 5-HT1A receptors: a. Naunyn-Schmiedeberg's archives of pharmacology. vol 363. issue 4. 2001-08-16. PMID:11330332. |
both 8-oh-dpat (1 microm) and 5-ht (10 microm) elicited a pronounced increase in [35s]gtpys binding in the dorsal raphe nucleus, which contains serotonergic cell bodies bearing 5-ht1a autoreceptors. |
2001-08-16 |
2023-08-12 |
Not clear |
| E Sørensen, J Grønli, B Bjorvatn, A Bjørkum, R Ursi. Sleep and waking following microdialysis perfusion of the selective 5-HT1A receptor antagonist p-MPPI into the dorsal raphe nucleus in the freely moving rat. Brain research. vol 897. issue 1-2. 2001-06-21. PMID:11282365. |
sleep and waking following microdialysis perfusion of the selective 5-ht1a receptor antagonist p-mppi into the dorsal raphe nucleus in the freely moving rat. |
2001-06-21 |
2023-08-12 |
rat |
| E Sørensen, J Grønli, B Bjorvatn, A Bjørkum, R Ursi. Sleep and waking following microdialysis perfusion of the selective 5-HT1A receptor antagonist p-MPPI into the dorsal raphe nucleus in the freely moving rat. Brain research. vol 897. issue 1-2. 2001-06-21. PMID:11282365. |
the aim of this study was to examine the involvement of the dorsal raphe nucleus (drn) presynaptic serotonergic 5-ht1a autoreceptors on sleep and waking parameters, in particular rapid eye movement (rem) sleep. |
2001-06-21 |
2023-08-12 |
rat |
| C Roberts, G W Pric. Interaction of serotonin autoreceptor antagonists in the rat dorsal raphe nucleus: an in vitro fast cyclic voltammetry study. Neuroscience letters. vol 300. issue 1. 2001-05-10. PMID:11172936. |
5-ht1a, 5-ht1b and 5-ht1d receptors are known to function as 5-ht autoreceptors in the rat dorsal raphe nucleus (drn), modulating local 5-ht efflux. |
2001-05-10 |
2023-08-12 |
rat |
| H Razani, Z Diaz-Cabiale, K Fuxe, S O Ogre. Intraventricular galanin produces a time-dependent modulation of 5-HT1A receptors in the dorsal raphe of the rat. Neuroreport. vol 11. issue 18. 2001-03-29. PMID:11192606. |
intraventricular galanin produces a time-dependent modulation of 5-ht1a receptors in the dorsal raphe of the rat. |
2001-03-29 |
2023-08-12 |
rat |
| Y Q Zhang, X Gao, Y L Huang, G C W. Expression of 5-HT1A receptor mRNA in rat dorsal raphe nucleus and ventrolateral periaqueductal gray neurons after peripheral inflammation. Neuroreport. vol 11. issue 15. 2001-02-08. PMID:11059903. |
expression of 5-ht1a receptor mrna in rat dorsal raphe nucleus and ventrolateral periaqueductal gray neurons after peripheral inflammation. |
2001-02-08 |
2023-08-12 |
rat |