| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Florian Gackière, Laurent Vina. Serotonergic modulation of post-synaptic inhibition and locomotor alternating pattern in the spinal cord. Frontiers in neural circuits. vol 8. 2015-05-15. PMID:25221477. |
this article will review the role of serotonin (5-ht), in particular 5-ht2 receptors, in shaping the alternating pattern. |
2015-05-15 |
2023-08-13 |
rat |
| Florian Gackière, Laurent Vina. Serotonergic modulation of post-synaptic inhibition and locomotor alternating pattern in the spinal cord. Frontiers in neural circuits. vol 8. 2015-05-15. PMID:25221477. |
experiments aimed at either reducing the endogenous level of serotonin in the spinal cord or blocking the activation of 5-ht2 receptors. |
2015-05-15 |
2023-08-13 |
rat |
| Alla Edward Lychkova, Valeria De Pasquale, Luigi Avallone, Alexander Michael Puzikov, Luigi Michele Pavon. Serotonin regulates contractile activity of the uterus in non-pregnant rabbits. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 165. 2015-04-09. PMID:24892885. |
these data suggest that 5-ht stimulation of the parasympathetic nerves results in the induction of uterine contraction via the activation of 5-ht2, 3, and 4 receptor subfamilies. |
2015-04-09 |
2023-08-13 |
Not clear |
| b' M R Kuznetsov, I V Kosykh, S M Iumin, N V Kunitsyn, V F Kuznetsova, V Iu Tolstikhin, L A Magnitski\\xc4\\xa. [Use of naftidrofuryl in angiology]. Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery. vol 20. issue 4. 2015-02-23. PMID:25490354.' |
the review analyses the role of serotonin in the development of pathological processes in angiological patients, showing its negative role in aggravating chronic and acute ischaemia of various organs (brain, myocardium, extremities) both at the expense of vasoconstriction and due to an increase in blood platelet aggregation of blood platelets and erythrocytes, followed by analysis of clinical efficacy of naftidrofuryl) - serotonin 5-ht2 receptor antagonist. |
2015-02-23 |
2023-08-13 |
Not clear |
| Keisuke Hazama, Atsuko Hayata-Takano, Kazuki Uetsuki, Atsushi Kasai, Naoki Encho, Norihito Shintani, Kazuki Nagayasu, Ryota Hashimoto, Dora Reglodi, Tsuyoshi Miyakawa, Takanobu Nakazawa, Akemichi Baba, Hitoshi Hashimot. Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice. PloS one. vol 9. issue 2. 2015-01-27. PMID:24586556. |
mice with homozygous disruption of the pacap gene display profound behavioral and neurological abnormalities that are ameliorated with the atypical antipsychotic and dopamine d2 and serotonin (5-ht)2 antagonist risperidone and the 5-ht2 receptor antagonist ritanserin; however, the underlying mechanisms remain unknown. |
2015-01-27 |
2023-08-12 |
mouse |
| Michelle R Lofwall, Paul A Nuzzo, Charles Campbell, Sharon L Wals. Aripiprazole effects on self-administration and pharmacodynamics of intravenous cocaine and cigarette smoking in humans. Experimental and clinical psychopharmacology. vol 22. issue 3. 2015-01-26. PMID:24467369. |
aripiprazole is a partial agonist at dopamine (d2) and serotonin (5-ht1a) receptors and 5-ht2 antagonist. |
2015-01-26 |
2023-08-12 |
human |
| E A Larson, M G Metzen, M J Chacro. Serotonin modulates electrosensory processing and behavior via 5-HT2-like receptors. Neuroscience. vol 271. 2015-01-13. PMID:24780766. |
here we show that the 5-ht2 receptor antagonist ketanserin (ket) can effectively block the effects of 5-ht on pyramidal neuron excitability in vitro. |
2015-01-13 |
2023-08-13 |
Not clear |
| E A Larson, M G Metzen, M J Chacro. Serotonin modulates electrosensory processing and behavior via 5-HT2-like receptors. Neuroscience. vol 271. 2015-01-13. PMID:24780766. |
thus, our results strongly suggest that the previously observed effects of 5-ht on sensory processing within ell and their consequences for behavior are mediated by 5-ht2 receptors. |
2015-01-13 |
2023-08-13 |
Not clear |
| Kyung Hoon Oh, Yoonjin Nam, Ji Hoon Jeong, In Kyeom Kim, Uy Dong Soh. The effect of DA-9701 on 5-hydroxytryptamine-induced contraction of feline esophageal smooth muscle cells. Molecules (Basel, Switzerland). vol 19. issue 4. 2014-11-25. PMID:24759073. |
5-ht binds to the 5-ht2, 5-ht3 and 5-ht4 receptors to induce smooth muscle contraction in feline esmcs. |
2014-11-25 |
2023-08-13 |
cat |
| Jacob Wienecke, Li-Qun Ren, Hans Hultborn, Meng Chen, Morten Møller, Yifan Zhang, Mengliang Zhan. Spinal cord injury enables aromatic L-amino acid decarboxylase cells to synthesize monoamines. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 36. 2014-11-10. PMID:25186745. |
the production of 5-ht by aadc cells, together with an upregulation of 5-ht2 receptors, offers a partial explanation of hyperreflexia below a chronic sci. |
2014-11-10 |
2023-08-13 |
rat |
| Costanza Burattini, Giulia Battistini, Francesco Tamagnini, Giorgio Aicard. Low-frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid. Journal of neurophysiology. vol 111. issue 5. 2014-10-30. PMID:24335217. |
present results suggest that lfs-4hz induces the release of 5-ht, which acts at 5-ht2 postsynaptic receptors, increasing ca(2+) influx through l-type voltage-gated channels and 2-arachidonoylglycerol production and release; the ecb travels retrogradely and binds to presynaptic cb1 receptors, causing a long-lasting decrease of glutamate release, resulting in ltd. |
2014-10-30 |
2023-08-12 |
rat |
| Francisca Cléa Florenço de Sousa, Iris Cristina Maia Oliveira, Maria Izabel Gomes Silva, Carla Thiciane Vasconcelos de Melo, Vívian Romero Santiago, Raquell de Castro Chaves, Mariana Lima Fernandes, Stanley Juan Chaves Gutierrez, Silvânia Maria Mendes Vasconcelos, Danielle Silveira Macêdo, José Maria Barbosa Filh. Involvement of monoaminergic system in the antidepressant-like effect of riparin I from Aniba riparia (Nees) Mez (Lauraceae) in mice. Fundamental & clinical pharmacology. vol 28. issue 1. 2014-10-07. PMID:22913717. |
the pretreatment of mice with prazosin (1 mg/kg, i.p., an α₁ -adrenoceptor antagonist), yohimbine (1 mg/kg, i.p., an α₂ -adrenoceptor antagonist), sch23390 (15 μg/kg, i.p., a dopamine d1 receptor antagonist), sulpiride (50 mg/kg, i.p., a dopamine d2 receptor antagonist), p-chlorophenylalanine (100 mg/kg, an inhibitor of serotonin synthesis) or ritanserin (4 mg/kg, a serotonin 5-ht2(a)/2(c) receptor antagonist) blocked the anti-immobility effects elicited by rip i (50 mg/kg, p.o.) |
2014-10-07 |
2023-08-12 |
mouse |
| Farideh A Javid, Stefano Pale. The effect of 5-HT and electrical field stimulation on the contractility of the whole isolated urinary bladder of Suncus murinus. European journal of pharmacology. vol 723. 2014-10-07. PMID:24513135. |
in conclusion, the 5-ht2 receptors are likely to play a role in mediating the contractile response to 5-ht in detrusor muscle. |
2014-10-07 |
2023-08-12 |
Not clear |
| Zana R Majeed, Audra Stacy, Robin L Coope. Pharmacological and genetic identification of serotonin receptor subtypes on Drosophila larval heart and aorta. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. vol 184. issue 2. 2014-09-29. PMID:24370737. |
furthermore, 5-ht2 antagonist, ketanserin, markedly reduces the positive chronotropic effect of 5-ht in a dose-response manner. |
2014-09-29 |
2023-08-12 |
drosophila_melanogaster |
| Zana R Majeed, Audra Stacy, Robin L Coope. Pharmacological and genetic identification of serotonin receptor subtypes on Drosophila larval heart and aorta. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. vol 184. issue 2. 2014-09-29. PMID:24370737. |
given these results, we conclude that these 5-ht2 receptor subtypes are involved in the action of 5-ht on the heart rate in the larval stage. |
2014-09-29 |
2023-08-12 |
drosophila_melanogaster |
| Cristina Miguelez, Teresa Morera-Herreras, Maria Torrecilla, Jose A Ruiz-Ortega, Luisa Uged. Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease. Frontiers in neural circuits. vol 8. 2014-09-24. PMID:24672433. |
the neurotransmitter serotonin (5-ht) has a multifaceted function in the modulation of information processing through the activation of multiple receptor families, including g-protein-coupled receptor subtypes (5-ht1, 5-ht2, 5-ht4-7) and ligand-gated ion channels (5-ht3). |
2014-09-24 |
2023-08-12 |
Not clear |
| Gerardo Aguirre Hernández, Ratnasamy Somanathan, Sylvain Bernè. Pelanserin: 3-[3-(4-phenyl-piperazin-1-yl)prop-yl]quinazoline-2,4(1H,3H)-dione. Acta crystallographica. Section E, Structure reports online. vol 70. issue Pt 8. 2014-09-24. PMID:25249922. |
the title compound, c21h24n4o2, is a potent serotonin 5-ht2 and α1-adrenoceptor antagonist. |
2014-09-24 |
2023-08-13 |
Not clear |
| Tomohisa Mori, Naoki Uzawa, Haruyo Kazawa, Hirohiko Watanabe, Ayano Mochizuki, Masahiro Shibasaki, Kazumi Yoshizawa, Kimio Higashiyama, Tsutomu Suzuk. Differential substitution for the discriminative stimulus effects of 3,4-methylenedioxymethamphetamine and methylphenidate in rats. The Journal of pharmacology and experimental therapeutics. vol 350. issue 2. 2014-08-26. PMID:24917544. |
on the other hand, serotonin (5-ht) receptor agonists 5-ht1a and 5-ht2 fully substituted for the discriminative stimulus effects of mdma. |
2014-08-26 |
2023-08-13 |
rat |
| Michael D Shuman, Ian R Mcgran. Rationale for iloperidone in the treatment of posttraumatic stress disorder. Innovations in clinical neuroscience. vol 11. issue 5-6. 2014-08-25. PMID:25152843. |
additional reduction in hypervigilance may occur through blockade of dopamine receptor d2 and serotonin receptors in the 5-ht2 family. |
2014-08-25 |
2023-08-13 |
Not clear |
| Yaqing Li, Lisa Li, Marilee J Stephens, Dwight Zenner, Katherine C Murray, Ian R Winship, Romana Vavrek, Glen B Baker, Karim Fouad, David J Bennet. Synthesis, transport, and metabolism of serotonin formed from exogenously applied 5-HTP after spinal cord injury in rats. Journal of neurophysiology. vol 111. issue 1. 2014-08-11. PMID:24068759. |
in contrast, when we applied exogenous 5-htp (in vitro or in vivo), aadc-containing vessels and neurons synthesized 5-ht, which contributed to increased motoneuron activity and muscle spasms (long-lasting reflexes, llrs), by acting on 5-ht2 receptors (sb206553 sensitive) located on motoneurons (ttx resistant). |
2014-08-11 |
2023-08-12 |
rat |