| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gordon F Buchanan, Haleigh R Smith, Amanda MacAskill, George B Richerso. 5-HT2A receptor activation is necessary for CO2-induced arousal. Journal of neurophysiology. vol 114. issue 1. 2016-03-28. PMID:25925320. |
5-ht2 receptor agonists were given to mice in which 5-ht neurons had been genetically eliminated during embryonic life (lmx1b(f/f/p)) and which are known to lack co2-induced arousal. |
2016-03-28 |
2023-08-13 |
mouse |
| T F Meert, F Awouter. Central 5-HT2 antagonists: A preclinical evaluation of a therapeutic potential. Acta neuropsychiatrica. vol 2. issue 4. 2016-03-09. PMID:26952556. |
a preclinical evaluation is presented of the serotonin 5-ht2 antagonists ritanserin and risperidone. |
2016-03-09 |
2023-08-13 |
Not clear |
| L K Burke, L K Heisle. 5-hydroxytryptamine medications for the treatment of obesity. Journal of neuroendocrinology. vol 27. issue 6. 2016-03-01. PMID:25925636. |
pharmacological agents targeting 5-ht receptors (5-htr), in combination with genetic models of 5-htr manipulation, have uncovered a role for specific 5-htrs in energy balance and reveal the 5-ht2 c r as the principal 5-htr mediating this homeostatic process. |
2016-03-01 |
2023-08-13 |
human |
| S V Chausova, K G Gurevich, G P Bondareva, O Ju Filatov, I Y Malyshe. [The role of cellular mediators in the development of the phenomenon of inhibition induced by barium sulfate luminol-dependent chemiluminescence of blood under the influence of non-steroidal anti-inflammatory drugs in patients with intolerance to these drugs]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. issue 3. 2016-02-23. PMID:26852602. |
it was found that the phenomenon of suppression slchl blood under the influence of nsaids in patients with intolerance is mediated by the participation of mediators, and the contribution of h1--and h2--histamine receptors, 5-ht2 serotonin receptors and cys-leukotriene receptors in the development of that phenomenon depends on the chemical nature of nsaids and the clinical manifestations of intolerance. |
2016-02-23 |
2023-08-13 |
Not clear |
| Małgorzata Zygmunt, Grażyna Chłoń-Rzepa, Jacek Sap. THE EFFECT OF SEROTONIN 5-HT1A, 5-HT2 RECEPTOR LIGANDS, KETOPROFEN AND THEIR COMBINATION IN MODELS OF INDUCED PAIN IN MICE. Acta poloniae pharmaceutica. vol 72. issue 3. 2016-01-11. PMID:26642666. |
the effect of serotonin 5-ht1a, 5-ht2 receptor ligands, ketoprofen and their combination in models of induced pain in mice. |
2016-01-11 |
2023-08-13 |
mouse |
| Rakesh Deelip Sonawane, Vijaykumar B Deore, Savita D Patil, Chandragouda R Patil, Sanjay J Surana, Ramesh K Goya. Role of 5-HT2 receptors in diabetes: Swertiamarin seco-iridoid glycoside might be a possible 5-HT2 receptor modulator. Physiology & behavior. vol 144. 2015-12-29. PMID:25708274. |
this warrants that swertiamarin might modulate 5-ht2 receptors rather than affecting the uptake of serotonin. |
2015-12-29 |
2023-08-13 |
Not clear |
| Sebastian Weiterer, Dagmar Schulte, Sabrina Müller, Thomas Kohlen, Florian Uhle, Markus A Weigand, Michael Henric. Tumor necrosis factor alpha induces a serotonin dependent early increase in ciliary beat frequency and epithelial transport velocity in murine tracheae. PloS one. vol 9. issue 3. 2015-12-14. PMID:24626175. |
the increases in ciliary beat frequency as well as the accelerated particle transport velocity were either inhibited by the unspecific serotonin antagonist methysergide or by cyproheptadine a specific 5-ht2 receptor antagonist. |
2015-12-14 |
2023-08-12 |
mouse |
| Chiara Ceci, Martina Proietti Onori, Simone Macrì, Giovanni Laviol. Interaction between the endocannabinoid and serotonergic system in the exhibition of head twitch response in four mouse strains. Neurotoxicity research. vol 27. issue 3. 2015-11-25. PMID:25516122. |
recent evidence indicates that tetrahydrocannabinol (thc), the principal psychoactive component of cannabis, reduced in mice the head twitch responses, a tic pharmacologically induced by the selective serotonin 5-ht2 receptor agonist 2,5-dimethoxy-4-iodoamphetamine (doi). |
2015-11-25 |
2023-08-13 |
mouse |
| Pavel A Puzerey, Michael J Decker, Roberto F Galá. Elevated serotonergic signaling amplifies synaptic noise and facilitates the emergence of epileptiform network oscillations. Journal of neurophysiology. vol 112. issue 10. 2015-10-19. PMID:25122717. |
augmented serotonin signaling also increases cortical network activity by enhancing synaptic excitation through activation of 5-ht2 receptors. |
2015-10-19 |
2023-08-13 |
Not clear |
| Takuya Yokoyama, Nobuaki Nakamuta, Tatsumi Kusakabe, Yoshio Yamamot. Serotonin-mediated modulation of hypoxia-induced intracellular calcium responses in glomus cells isolated from rat carotid body. Neuroscience letters. vol 597. 2015-10-19. PMID:25937361. |
the frequency and magnitude of hypoxia-induced [ca(2+)]i changes observed in the glomus cells were enhanced in the presence of 5-ht, and this response was inhibited by the 5-ht2 receptor antagonist, ketanserin. |
2015-10-19 |
2023-08-13 |
rat |
| Anderson Manoel Herculano, Bruna Puty, Vanessa Miranda, Monica Gomes Lima, Caio Maximin. Interactions between serotonin and glutamate-nitric oxide pathways in zebrafish scototaxis. Pharmacology, biochemistry, and behavior. vol 129. 2015-10-09. PMID:25536532. |
nmda receptors have been implicated in the acute response to stress, possibly mediated the nitric oxide pathway; serotonin has also been implicated in these responses, and has recently been shown to modulate the nitric oxide pathway via 5-ht1 and 5-ht2 receptors. |
2015-10-09 |
2023-08-13 |
zebrafish |
| P I Yanchuk, S M Athamnah, E M Reshetnik, J A Levadyanska, N O Nikitina, S P Veselsk. [ROLE OF SEROTONIN IN THE REGULATION OF RESPIRATION AND BILE SECRETORY FUNCTION OF THE LIVER]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 61. issue 2. 2015-10-06. PMID:26387167. |
introduction of serotonin in the conditions of 5-ht2 receptors blockade by ketanserin also led to speed decrease of bile secretion, but in this case stimulating effect of autacoid on bile acid conjugation with taurine and glycine wasn't manifested and content of free cholate wasn't reduced. |
2015-10-06 |
2023-08-13 |
rat |
| Konstantinos N Tzirogiannis, Kalliopi T Kourentzi, Sofia Zyga, Vassiliki Papalimneou, Maria Tsironi, Agni D Grypioti, Ioannis Protopsaltis, Dimitrios Panidis, Georgios I Panoutsopoulo. Effect of 5-HT7 receptor blockade on liver regeneration after 60-70% partial hepatectomy. BMC gastroenterology. vol 14. 2015-10-05. PMID:25433672. |
the effect of serotonin, as an incomplete mitogen, on liver regeneration has recently been unveiled and is mediated through 5-ht2 receptor. |
2015-10-05 |
2023-08-13 |
Not clear |
| D Sarrouilhe, J Clarhaut, N Defamie, M Mesni. Serotonin and cancer: what is the link? Current molecular medicine. vol 15. issue 1. 2015-09-16. PMID:25601469. |
serotonin exhibits a growth stimulatory effect in aggressive cancers and carcinoids more often through 5- ht1 and 5-ht2 receptors. |
2015-09-16 |
2023-08-13 |
Not clear |
| Moe Igari, Hao-Wei Shen, Yoko Hagino, Setsu Fukushima, Yoshiyuki Kasahara, Klaus-Peter Lesch, Dennis L Murphy, Frank Scott Hall, George R Uhl, Kazutaka Ikeda, Nobuo Yaegashi, Ichiro Sor. Attenuated methamphetamine-induced locomotor sensitization in serotonin transporter knockout mice is restored by serotonin 1B receptor antagonist treatment. Behavioural pharmacology. vol 26. issue 1-2. 2015-09-03. PMID:25485646. |
the present experiments examined serotonergic roles in meth-induced locomotor sensitization by assessing: (a) the effect of serotonin transporter (sert; slc6a4) knockout (ko) on meth-induced locomotor sensitization; (b) extracellular monoamine levels in meth-treated animals as determined by in-vivo microdialysis; and (c) effects of serotonin (5-ht) receptor antagonists on meth-induced behavioral sensitization, with focus on effects of the 5-ht1b receptor antagonist sb 216641 and a comparison with the 5-ht2 receptor antagonist ketanserin. |
2015-09-03 |
2023-08-13 |
mouse |
| Takuya Yokoyama, Nobuaki Nakamuta, Tatsumi Kusakabe, Yoshio Yamamot. Sympathetic regulation of vascular tone via noradrenaline and serotonin in the rat carotid body as revealed by intracellular calcium imaging. Brain research. vol 1596. 2015-08-24. PMID:25463023. |
however, na did not induce [ca(2+)]i increases in pericytes in capillaries, whereas 5-ht did and this response was inhibited by the 5-ht2 receptor antagonist, ketanserin. |
2015-08-24 |
2023-08-13 |
rat |
| Yunpeng Du, Megan Cramer, Chieh Allen Lee, Jie Tang, Arivalagan Muthusamy, David A Antonetti, Hui Jin, Krzysztof Palczewski, Timothy S Ker. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 5. 2015-07-30. PMID:25667222. |
this response was reduced or ablated by pharmacologic inhibition of the α1-ar (a gq-coupled receptor) or gs-coupled serotonin (5-ht2, 5-ht4, 5-ht6, and 5-ht7) receptors or by activation of the gi-coupled α2-ar. |
2015-07-30 |
2023-08-13 |
mouse |
| Mohammad Nasehi, Mehdi Jamshidi-Mehr, Fatemeh Khakpai, Mohammad-Reza Zarrindas. Possible involvement of CA1 5-HT1B/1D and 5-HT2A/2B/2C receptors in harmaline-induced amnesia. Pharmacology, biochemistry, and behavior. vol 125. 2015-07-28. PMID:25181578. |
moreover, intra-ca1 administration of 5-ht1b/1d receptor agonist, cp94253 (5 ng/mouse), 5-ht1b/1d receptor antagonist, gr127935 (0.05 and 0.5 ng/mouse), 5-ht2a/2b/2c receptor agonist, α-methyl 5-ht (0.5 ng/mouse) and 5-ht2 receptor antagonist, cinancerine (0.5 ng/mouse) impaired memory acquisition, but did not affect locomotor activity and tail flick. |
2015-07-28 |
2023-08-13 |
mouse |
| R Davis, M I Wild. Mirtazapine : A Review of its Pharmacology and Therapeutic Potential in the Management of Major Depression. CNS drugs. vol 5. issue 5. 2015-06-16. PMID:26071050. |
the increased release of serotonin (5-hydroxytryptamine; 5-ht) stimulates serotonin 5-ht1 receptors because mirtazapine directly blocks 5-ht2 and 5-ht3 receptors. |
2015-06-16 |
2023-08-13 |
Not clear |
| Leonard L Howell, Kathryn A Cunningha. Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder. Pharmacological reviews. vol 67. issue 1. 2015-06-15. PMID:25505168. |
serotonin 5-ht2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder. |
2015-06-15 |
2023-08-13 |
Not clear |