| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chengyi Huang, Yufeng Y. Synergistic Cytotoxicity of β-Elemene and Cisplatin in Gingival Squamous Cell Carcinoma by Inhibition of STAT3 Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-04-24. PMID:28355175. |
mtt assay, clonogenic assay, annexin v/pi apoptosis assay, western blot analysis, and xenograft model treatment were carried out in vitro and in vivo. |
2017-04-24 |
2023-08-13 |
Not clear |
| Shi Zhong, You-Gui Li, Dong-Feng Ji, Tian-Bao Lin, Zhi-Qiang L. Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells. Molecules (Basel, Switzerland). vol 21. issue 7. 2017-04-18. PMID:27447597. |
we performed an in vitro study involving mtt, flow cytometry, rt-pcr, and western blot analyses to investigate the effects of pca treatment on cell proliferation, cell cycle distribution, apoptosis, and expression of several cell cycle-related genes in ht-29 cells. |
2017-04-18 |
2023-08-13 |
human |
| In-Su Kim, Palanivel Ganesan, Dong-Kug Cho. Cx43 Mediates Resistance against MPP⁺-Induced Apoptosis in SH-SY5Y Neuroblastoma Cells via Modulating the Mitochondrial Apoptosis Pathway. International journal of molecular sciences. vol 17. issue 11. 2017-04-10. PMID:27809287. |
in another experiment, we demonstrated that over-expression of cx43 in the sh-sy5y cell system decreased mpp⁺-induced apoptosis based on the mtt assay and reduced the bax/bcl-2 ratio and the release of cytochrome c based on western blot analysis. |
2017-04-10 |
2023-08-13 |
human |
| Chunyuan Liu, Aihong Zhang, Lei Cheng, Yang Ga. miR‑410 regulates apoptosis by targeting Bak1 in human colorectal cancer cells. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27177325. |
cell growth and apoptosis was tested using an mtt assay, western blot and cytochrome c assay. |
2017-04-06 |
2023-08-13 |
human |
| Yiqun Yao, Yongjian Liu, Xiupeng Lv, Bin Dong, Feng Wang, Jun Li, Qiuping Zhang, Ruixue Xu, Yinghui X. Down-regulation of ribosomal protein S15A inhibits proliferation of human glioblastoma cells in vivo and in vitro via AKT pathway. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 4. 2017-02-13. PMID:26537582. |
molecular mechanisms and the effect of rps15a on cell growth and migration were investigated by using western blot, mtt assay, wound healing assay, transwell migration assay, and tumorigenesis in nude mice. |
2017-02-13 |
2023-08-13 |
mouse |
| Bing Liang, Wei Wei, Jianta Wang, Mingming Zhang, Ran Xu, Fei Wu, Haitao Xiao, Lei Tan. Protective effects of Semiaquilegia adoxoides n-butanol extract against hydrogen peroxide-induced oxidative stress in human lens epithelial cells. Pharmaceutical biology. vol 54. issue 9. 2017-02-13. PMID:26974044. |
the antioxidant effects of nsa were determined in terms of cell viability (mtt assay), apoptosis (annexinv/pi staining), radical scavenging capability (various enzymatic assays), loss of mitochondrial membrane potential (rhodamine 123 staining), expression of apoptotic markers including caspase-3 and caspase-9 and the change of bcl-2/bax ratio (western blot) in the hle cells. |
2017-02-13 |
2023-08-13 |
human |
| Yan-Ran Wu, Hai-Jun Qi, Dan-Fang Deng, Ying-Ying Luo, Sheng-Lan Yan. MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 9. 2017-02-13. PMID:27188433. |
western blot was used for detection of pten, p13k, and akt protein expressions, mtt method for cell proliferation, transwell assay for cell migration and invasion, and flow cytometry for cell cycle and apoptosis. |
2017-02-13 |
2023-08-13 |
human |
| Shuo Zhang, Lei Gao, Asmitananda Thakur, Puyu Shi, Feng Liu, Jing Feng, Ting Wang, Yiqian Liang, Johnson J Liu, Mingwei Chen, Hui Re. miRNA-204 suppresses human non-small cell lung cancer by targeting ATF2. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-08. PMID:26935060. |
rna isolation, qrt-pcr, mtt, colony formation assay, cell cycle assay, cell apoptosis assay, cell migration assay, and western blot were performed. |
2017-02-08 |
2023-08-13 |
human |
| Zahra Goodarzi, Hoorieh Soleimanjahi, Ehsan Arefian, Esmaeil Saberfa. The effect of bovine rotavirus and its nonstructural protein 4 on ER stress-mediated apoptosis in HeLa and HT-29 cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-07. PMID:26427658. |
mtt, flow cytometry, and western blot were used to evaluate the cell viability, apoptosis, and expression level of c/ebp-homologous protein (chop) and activated caspase-4. |
2017-02-07 |
2023-08-13 |
cattle |
| Wei Dai, Quangen Gao, Jianping Qiu, Jianmao Yuan, Guoliang Wu, Genhai She. Quercetin induces apoptosis and enhances 5-FU therapeutic efficacy in hepatocellular carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 5. 2017-02-06. PMID:26628295. |
the antiproliferative effects of q were measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), and the apoptosis and cell cycle dynamics were assessed by flow cytometry; the expression of apoptosis-associated proteins were evaluated by western blot and immunohistochemistry staining; the tumor growth in vivo was evaluated in a xenograft mouse model. |
2017-02-06 |
2023-08-13 |
mouse |
| Qianfeng Fu, Yuling Jiang, Daxin Zhang, Xiuli Liu, Junfeng Guo, Jinlong Zha. Valosin-containing protein (VCP) promotes the growth, invasion, and metastasis of colorectal cancer through activation of STAT3 signaling. Molecular and cellular biochemistry. vol 418. issue 1-2. 2017-02-02. PMID:27344168. |
cell proliferation, invasion, apoptosis, and cell cycle arrest were subsequently examined by mtt assay, transwell chamber assay, flow cytometry, and western blot analysis, respectively. |
2017-02-02 |
2023-08-13 |
mouse |
| Shan Huang, Hai Feng Liu, Xianghua Quan, Yan Jin, Guangshan Xuan, Ren-Bo An, Tsering Dikye, Bin L. Rhamnella gilgitica Attenuates Inflammatory Responses in LPS-Induced Murine Macrophages and Complete Freund's Adjuvant-Induced Arthritis Rats. The American journal of Chinese medicine. vol 44. issue 7. 2017-01-27. PMID:27785942. |
the effects of rg on cell viability were determined by a mtt assay, and the effects of rg on pro-inflammatory mediators were analyzed by elisa and western blot. |
2017-01-27 |
2023-08-13 |
rat |
| Xuxia Tang, Chen Zhang, Jiongzhou Wei, Yuting Fang, Rongxiang Zhao, Jianxin Y. Apoptosis is induced by shikonin through the mitochondrial signaling pathway. Molecular medicine reports. vol 13. issue 4. 2016-12-28. PMID:26935754. |
mtt, annexin v‑phycoerythrin/7‑aminoactinomycin d staining, electron microscopy and jc‑1 probe staining were performed to analyze mitochondrial membrane potential, and western blot analysis was used to examine the activation of the mitochondrial signaling pathway, and the changes in mitochondrial apoptosis pathway‑associated protein expression. |
2016-12-28 |
2023-08-13 |
human |
| Xiaofen Pan, Rui Meng, Zhonghua Yu, Jingjing Mou, Sha Liu, Ziyi Sun, Zhenwei Zou, Gang Wu, Gang Pen. Quinalizarin enhances radiosensitivity of nasopharyngeal carcinoma cells partially by suppressing SHP-1 expression. International journal of oncology. vol 48. issue 3. 2016-11-10. PMID:26781335. |
cell viability, survival, dna double-strand breaks (dsb), apoptosis, cell cycle distribution, expression of shp-1 and other related proteins were detected with mtt assay, colony formation assay, immunofluorescent assay, flow cytometry and western blot analysis, respectively. |
2016-11-10 |
2023-08-13 |
human |
| Ting Pi, Xiao-Wen Zhou, Liang Cai, Wei Zhang, Chao-Fen Su, Wu-Tian Wu, Xiao-Ming Ren, Huan-Min Lu. PI3K/Akt signaling pathway is involved in the neurotrophic effect of senegenin. Molecular medicine reports. vol 13. issue 2. 2016-10-27. PMID:26647727. |
primary cortical rat neurons were treated with various pharmacological antagonists and with or without senegenin, and subjected to mtt and western blot analysis to explore the effects of senegenin on cell survival as well as the activation of signaling pathways. |
2016-10-27 |
2023-08-13 |
rat |
| Zhi-jian Meng, Ke Ta. Enhancement of Chemosensitivity by Stathmin-1 Silencing in Gastric Cancer Cells In Situ and In Vivo. Oncology research. vol 23. issue 1-2. 2016-10-24. PMID:26802649. |
the cell growth inhibition, expression of associated proteins, cell cycle, and apoptosis were evaluated by mtt, western blot, and flow cytometric assays, respectively. |
2016-10-24 |
2023-08-13 |
Not clear |
| Yi-Jin Li, Bao-Kang Dong, Meng Fan, Wen-Xue Jian. BTG2 inhibits the proliferation and metastasis of osteosarcoma cells by suppressing the PI3K/AKT pathway. International journal of clinical and experimental pathology. vol 8. issue 10. 2016-10-05. PMID:26722427. |
the effects of btg2 on cell proliferation, migration and invasion were explored by mtt, transwell assays, western blot, and in vivo tumorigenesis in nude mice. |
2016-10-05 |
2023-08-13 |
mouse |
| Min Hee Sung, Ok-Kyoung Kwon, Sei-Ryang Oh, Joongku Lee, Sang-Hong Park, Sang Bae Han, Kyung-Seop Ah. Azorella compacta methanolic extract induces apoptosis via activation of mitogen-activated protein kinase. Molecular medicine reports. vol 12. issue 5. 2016-08-26. PMID:26397193. |
apoptosis induction was measured by mtt assay, fluorescence microscopy, dna fragmentation assay, flow cytometric analysis, reverse transcription quantitative polymerase chain reaction and western blot analyses. |
2016-08-26 |
2023-08-13 |
human |
| Hongfei Ren, Hongyu Ren, Xue Li, Dongdong Yu, Shuai Mu, Zhiguang Chen, Qin F. Effects of intermedin on proliferation, apoptosis and the expression of OPG/RANKL/M-CSF in the MC3T3-E1 osteoblast cell line. Molecular medicine reports. vol 12. issue 5. 2016-08-26. PMID:26398911. |
cell proliferation, apoptosis and the expression of receptor activator of nf‑κb ligand (rankl), osteoprotegerin (opg) and macrophage colony‑stimulating factor (m‑csf) were measured following treatment using multiple detection techniques, including an mtt assay, flow cytometry, reverse transcription‑quantitative polymerase chain reaction and western blot analysis. |
2016-08-26 |
2023-08-13 |
Not clear |
| Fei-Ting Hsu, Yu-Chang Liu, Tsu-Te Liu, Jeng-Jong Hwan. Curcumin Sensitizes Hepatocellular Carcinoma Cells to Radiation via Suppression of Radiation-Induced NF-κB Activity. BioMed research international. vol 2015. 2016-08-18. PMID:26539482. |
the effects of curcumin, radiation, and combination of both on cell viability, apoptosis, nf-κb activation, and expressions of nf-κb downstream effector proteins were investigated with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), nf-κb reporter gene, mitochondrial membrane potential (mmp), electrophoretic mobility shift (emsa), and western blot assays in huh7-nf-κb-luc2, hep3b, and hepg2 cells. |
2016-08-18 |
2023-08-13 |
human |