| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng Wu, Meng-Ni Li, Yi-Wei Feng, Xiao-Fei He, Wan-Qi Li, Feng-Yin Liang, Xue Li, Ge Li, Zhong Pei, Yue Lan, Guang-Qing X. Continuous theta burst stimulation provides neuroprotection by accelerating local cerebral blood flow and inhibiting inflammation in a mouse model of acute ischemic stroke. Brain research. vol 1726. 2021-03-29. PMID:31586625. |
treatment with ctbs resulted in a reduction in the volume of the infarct region and significantly increased vascular diameter and blood flow velocity in peri-infarct region, as well as decreased the numbers of calcium binding adapter molecule 1 (iba-1)-positive microglia and glial fibrillary acidic protein (gfap)-positive astrocytes. |
2021-03-29 |
2023-08-13 |
mouse |
| Jing Wang, Simin Lai, Guodong Li, Ting Zhou, Biao Wang, Fang Cao, Teng Chen, Xia Zhang, Yanjiong Che. Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31626970. |
d3rko mice exhibited a large number of iba1-labelled microglia in the absence of glial fibrillary acidic protein (gfap)-labelled astrocytes in mesolimbic dopaminergic brain areas. |
2021-03-08 |
2023-08-13 |
mouse |
| Samantha L Hodges, Suzanne O Nolan, Lindsay A Tomac, Ilyasah D A Muhammad, Matthew S Binder, Joseph H Taube, Joaquin N Lug. Lipopolysaccharide-induced inflammation leads to acute elevations in pro-inflammatory cytokine expression in a mouse model of Fragile X syndrome. Physiology & behavior. vol 215. 2021-03-04. PMID:31838149. |
there were no differences in hippocampal protein expression between genotypes in microglia (iba1) or astrocyte (gfap) reactivity. |
2021-03-04 |
2023-08-13 |
mouse |
| Jorge Miguel Amaya, Ernst Suidgeest, Isabelle Sahut-Barnola, Typhanie Dumontet, Nathanaëlle Montanier, Guilhem Pagès, Cécile Keller, Louise van der Weerd, Alberto M Pereira, Antoine Martinez, Onno C Meije. Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse. Frontiers in neuroscience. vol 15. 2021-03-03. PMID:33642975. |
we also observed a decrease in the expression of glial fibrillary acidic protein (gfap, a marker for reactive astrocytes) and ionized calcium-binding adapter molecule 1 (iba1, a marker for activated microglia) in the cingulate regions of the anterior corpus callosum and the hippocampus. |
2021-03-03 |
2023-08-13 |
mouse |
| Jaspreet Kaur, Eller Cont. Dataset on inflammation induced after lumbar puncture. Data in brief. vol 34. 2021-02-02. PMID:33521177. |
data presented in the article implicate active microglia measured by using protein biomarker such as iba-1 [1, 3] and astrocytes measured by using glial fibrillary acidic protein (gfap) [2, 3] and s100 (strongly targets s100b and weakly a1) [7, 8] in the csf collected two-three weeks after the laminectomy and dura breakage from the adult rats. |
2021-02-02 |
2023-08-13 |
rat |
| Jaspreet Kaur, Eller Cont. Dataset on inflammation induced after lumbar puncture. Data in brief. vol 34. 2021-02-02. PMID:33521177. |
western blots were performed with the collected csf which showed high expression of glial markers such as gfap, iba-1 and s100 which has shown to target s100b with no expression of a1 (or a2, play an important role in neuroprotection) astrocytes which have recently been shown to be produced by microglia at the site of injury [9]. |
2021-02-02 |
2023-08-13 |
rat |
| Estibaliz Etxeberria-Rekalde, Saioa Alzola-Aldamizetxebarria, Stefanie Flunkert, Isabella Hable, Magdalena Daurer, Joerg Neddens, Birgit Hutter-Paie. Quantification of Huntington's Disease Related Markers in the R6/2 Mouse Model. Frontiers in molecular neuroscience. vol 13. 2021-01-30. PMID:33505246. |
additionally, increased astrocytosis and activated microglia were observed by gfap, iba1 and tspo labeling, illustrating, that tspo is a more sensitive marker for early neuroinflammation compared to gfap and iba1. |
2021-01-30 |
2023-08-13 |
mouse |
| Yiying Zhou, Xiang Wu, Luying Ye, Yujing Bai, Hui Zhang, Zhenquan Xuan, Yi Feng, Panpan Zhang, Yi Chen, Yushan Yan, Binbin Zhu, Wei Cu. Edaravone at high concentrations attenuates cognitive dysfunctions induced by abdominal surgery under general anesthesia in aged mice. Metabolic brain disease. vol 35. issue 2. 2021-01-29. PMID:31916204. |
edaravone could also decrease glial fibrillary acidic protein (gfap) and ionized calcium binding adaptor molecule-1 (iba-1) positive areas in the hippocampal regions of surgery mice, suggesting that edaravone might inhibit surgery-induced over-activation of microglia and astrocytes. |
2021-01-29 |
2023-08-13 |
mouse |
| Jérôme Roy, Laurence Larroquet, Anne Surget, Anthony Lanuque, Franck Sandres, Frederic Terrier, Geneviève Corraze, Jetty Chung-Yung Lee, Sandrine Skiba-Cass. Impact on cerebral function in rainbow trout fed with plant based omega-3 long chain polyunsaturated fatty acids enriched with DHA and EPA. Fish & shellfish immunology. vol 103. 2021-01-25. PMID:32473359. |
however, the mrna expression of transcripts related to cell specification were down regulated, namely tmem119 markers of microglial cell in forebrain and midbrain, gfap markers of astrocyte in the midbrain, and rbfox3 markers of neurons in the midbrain and hindbrain in juveniles fed high ω-3 experimental diet. |
2021-01-25 |
2023-08-13 |
Not clear |
| Audrey Yi Tyan Peng, Ira Agrawal, Wan Yun Ho, Yi-Chun Yen, Ashley J Pinter, Jerry Liu, Qi Xuan Cheryl Phua, Katrianne Bethia Koh, Jer-Cherng Chang, Emma Sanford, Jodie Hon Kiu Man, Peiyan Wong, David H Gutmann, Greg Tucker-Kellogg, Shuo-Chien Lin. Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 46. 2021-01-25. PMID:33127758. |
herein, we show that tdp-43-deleted astrocytes exhibit a cell-autonomous increase in gfap immunoreactivity without affecting astrocyte or microglia proliferation. |
2021-01-25 |
2023-08-13 |
mouse |
| Joji Kunihiro, Hiroaki Nabeka, Hiroyuki Wakisaka, Kana Unuma, Md Sakirul Islam Khan, Tetsuya Shimokawa, Farzana Islam, Takuya Doihara, Kimiko Yamamiya, Shouichiro Saito, Fumihiko Hamada, Seiji Matsud. Prosaposin and its receptors GRP37 and GPR37L1 show increased immunoreactivity in the facial nucleus following facial nerve transection. PloS one. vol 15. issue 12. 2021-01-14. PMID:33259479. |
following facial nerve transection, many small iba1- and glial fibrillary acidic protein (gfap)-positive cells with strong gpr37l1 immunoreactivity, including microglia and astrocytes, were observed predominately on the operated side. |
2021-01-14 |
2023-08-13 |
rat |
| Henghua Jiang, Liqin Xu, Wen Liu, Mian Xiao, Jin Ke, Xing Lon. Chronic Pain Causes Peripheral and Central Responses in MIA-Induced TMJOA Rats. Cellular and molecular neurobiology. 2021-01-02. PMID:33387118. |
second, the period of tmjoa chronic pain was further explored by assessing the numbers of glial fibrillary acidic protein (gfap)-positive astrocytes and ionized calcium-binding adaptor molecule 1 (iba-1)-positive microglia in the trigeminal spinal nucleus (tsn) and performing nonsteroidal anti-inflammatory drug (nsaid) efficacy experiments. |
2021-01-02 |
2023-08-13 |
rat |
| Takuya Ikenari, Hirofumi Kurata, Takemasa Satoh, Yoshio Hata, Tetsuji Mor. Evaluation of Fluoro-Jade C Staining: Specificity and Application to Damaged Immature Neuronal Cells in the Normal and Injured Mouse Brain. Neuroscience. vol 425. 2020-12-15. PMID:31785351. |
fjc negative (-) apoptotic cells expressing activated caspase 3 were also observed, and a small number of fjc(+)/ionized calcium-binding adaptor molecule 1 (iba1)(+) microglia and fjc(+)/glial fibrillary acidic protein (gfap)(+) astrocytes were observed in the normal brain. |
2020-12-15 |
2023-08-13 |
mouse |
| Ola A Hussein, Asmaa Fathi Abdel Mola, Amal Rate. Tramadol administration induced hippocampal cells apoptosis, astrogliosis, and microgliosis in juvenile and adult male mice, histological and immunohistochemical study. Ultrastructural pathology. vol 44. issue 1. 2020-12-14. PMID:31924115. |
astrogliosis and microgliosis were proved by the increased immunoreactivity of astrocytes to glial fibrillary acidic protein (gfap) and microglia to cd68. |
2020-12-14 |
2023-08-13 |
mouse |
| Adriel Barrios-Anderson, Xiaodi Chen, Sakura Nakada, Ray Chen, Yow-Pin Lim, Barbara S Stonestree. Inter-alpha Inhibitor Proteins Modulate Neuroinflammatory Biomarkers After Hypoxia-Ischemia in Neonatal Rats. Journal of neuropathology and experimental neurology. 2020-12-08. PMID:31274164. |
hiaips reduced quantities of cortical gfap, hippocampal iba-1-positive microglia, corpus callosum mpo, and cortical mmp9-mpo cells and the percent of neutrophils in peripheral blood after hi in male, but not female rats. |
2020-12-08 |
2023-08-13 |
human |
| Takashi Fujishiro, Megumi Honjo, Hiroshi Kawasaki, Ryo Asaoka, Reiko Yamagishi, Makoto Aihar. Structural Changes and Astrocyte Response of the Lateral Geniculate Nucleus in a Ferret Model of Ocular Hypertension. International journal of molecular sciences. vol 21. issue 4. 2020-12-07. PMID:32079216. |
immunohistochemical analysis with antibodies against neun, glial fibrillary acidic protein (gfap), and iba-1 was performed to specifically label neurons, astrocytes, and microglia in the lgn. |
2020-12-07 |
2023-08-13 |
Not clear |
| Jatuporn Namyen, Kannika Permpoonputtana, Chutikorn Nopparat, Jiraporn Tocharus, Chainarong Tocharus, Piyarat Govitrapon. Protective Effects of Melatonin on Methamphetamine-Induced Blood-Brain Barrier Dysfunction in Rat Model. Neurotoxicity research. vol 37. issue 3. 2020-12-04. PMID:31900895. |
our results also showed the protective effects of melatonin against meth neurotoxic profiles, characterized by reactive gliosis: microglia (integrin-αm) and astrocyte (gfap); an excessive upregulation of primary pro-inflammatory cytokines: interleukin-1β (il-1β), interleukin-6 (il-6), and tumor necrosis factor-α (tnf-α); activation of neuroinflammatory signaling: nuclear factor-kappa b (nf-κb); and suppression of anti-oxidative signaling: nuclear factor erythroid 2-related factor (nrf2), that may exacerbate bbb structural impairment. |
2020-12-04 |
2023-08-13 |
rat |
| Francesca Siani, Rosaria Greco, Giovanna Levandis, Cristina Ghezzi, Francesca Daviddi, Chiara Demartini, Elisabetta Vegeto, Marie-Thérèse Fuzzati-Armentero, Fabio Blandin. Influence of Estrogen Modulation on Glia Activation in a Murine Model of Parkinson's Disease. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28620274. |
animals were sacrificed at different time points following 6-ohda injection and brain sections containing striatum and substantia nigra pars compacta (snc) underwent immunohistochemistry for tyrosine hydroxylase (th) (dopaminergic marker), immunofluorescence for iba1 and gfap (markers of microglia and astrocyte activation, respectively) and triple immunoflorescent to identify polarization of microglia toward the cytotoxic m1 (dapi/iba1/tnfα) or cytoprotective m2 (dapi/iba1/cd206) phenotype. |
2020-10-01 |
2023-08-13 |
mouse |
| Oluwabusayo R Folarin, Amanda M Snyder, Douglas G Peters, Funmilayo Olopade, James R Connor, James O Olopad. Brain Metal Distribution and Neuro-Inflammatory Profiles after Chronic Vanadium Administration and Withdrawal in Mice. Frontiers in neuroanatomy. vol 11. 2020-10-01. PMID:28790895. |
also, haematoxylin and eosin (h&e) staining of brain sections, and immunohistochemistry for microglia (iba-1), astrocytes (gfap), neurons (neu-n) and neu-n + 4',6-diamidine-2'-pheynylindole dihydrochloride (dapi) immunofluorescent labeling were observed for morphological and morphometric parameters. |
2020-10-01 |
2023-08-13 |
mouse |
| Sandra Bien-Möller, Ellen Balz, Susann Herzog, Laura Plantera, Silke Vogelgesang, Kerstin Weitmann, Carolin Seifert, Matthias A Fink, Sascha Marx, Angela Bialke, Chitra Venugopal, Sheila K Singh, Wolfgang Hoffmann, Bernhard H Rauch, Henry W S Schroede. Association of Glioblastoma Multiforme Stem Cell Characteristics, Differentiation, and Microglia Marker Genes with Patient Survival. Stem cells international. vol 2018. 2020-10-01. PMID:29535786. |
here, we performed expression analyses of stem cell (abcg2, cd44, cd95, cd133, elf4, nanog, and nestin) as well as differentiation and microglia markers (gfap, iba1, and sparc) in gbm compared to nonmalignant brain. |
2020-10-01 |
2023-08-13 |
Not clear |