| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rossana Tozzi, Giuseppina Palladini, Silvia Fallarini, Rosanna Nano, Chiara Gatti, Cristina Presotto, Antonio Schiavone, Rosella Micheletti, Patrizia Ferrari, Roberto Fogari, Stefano Perlin. Matrix metalloprotease activity is enhanced in the compensated but not in the decompensated phase of pressure overload hypertrophy. American journal of hypertension. vol 20. issue 6. 2007-07-26. PMID:17531925. |
during the transition of pressure overload hypertrophy (poh) to heart failure (hf) there is intense interstitial cardiac remodeling, characterized by a complex balance between collagen deposition and degradation by matrix metalloproteases (mmps). |
2007-07-26 |
2023-08-12 |
Not clear |
| Tatsuo Okada, Jun Wada, Kazuyuki Hida, Jun Eguchi, Izumi Hashimoto, Masako Baba, Akihiro Yasuhara, Kenichi Shikata, Hirofumi Makin. Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms. Diabetes. vol 55. issue 6. 2007-07-23. PMID:16731829. |
although similar hba(1c) levels were observed in both groups, pioglitazone significantly inhibited glomerular hypertrophy and mesangial matrix expansion and reduced urinary albumin excretion compared with the insulin-treated group. |
2007-07-23 |
2023-08-12 |
mouse |
| Giovanni de Simone, Oreste de Divitii. Extracellular matrix and left ventricular mechanics in overload hypertrophy. Advances in clinical pathology : the official journal of Adriatic Society of Pathology. vol 6. issue 1. 2007-07-19. PMID:17582942. |
extracellular matrix and left ventricular mechanics in overload hypertrophy. |
2007-07-19 |
2023-08-12 |
Not clear |
| Elena V Tchetina, Masahiko Kobayashi, Tadashi Yasuda, Tineke Meijers, Isabelle Pidoux, A Robin Pool. Chondrocyte hypertrophy can be induced by a cryptic sequence of type II collagen and is accompanied by the induction of MMP-13 and collagenase activity: implications for development and arthritis. Matrix biology : journal of the International Society for Matrix Biology. vol 26. issue 4. 2007-07-18. PMID:17306969. |
our results show that the induction of collagenase activity by a cryptic peptide sequence of type ii collagen, is accompanied by chondrocyte hypertrophy and associated with cellular and matrix changes. |
2007-07-18 |
2023-08-12 |
cattle |
| Bradley Stringer, Rachel Waddington, Alastair Sloan, Ian Phillips, Gary Telford, David Hughes, Geoffrey Craig, Lavinia Gangemi, Ian Brook, Christine Freeman, Xuesong Cao, Mandeep Gosal, Simon Smith, Graham Russell, George Foste. Bespoke human hypertrophic chondrocytic cell lines provide the osteoinductive signals required for vascularized bone formation. Tissue engineering. vol 13. issue 1. 2007-07-17. PMID:17518587. |
it also demonstrates that matrix material generated from human immortalized hypertrophic chondrocytic cells may provide an abundant, efficacious, and safer alternative to bone autograft--the currently preferred material for fracture repair. |
2007-07-17 |
2023-08-12 |
human |
| Deepa H Kumbar, Andrew VanBergen, Catherina Ocampo, Sunthorn Muangmingsuk, Andrew J Griffin, Madhu Gupt. Adapter molecule DOC-2 is differentially expressed in pressure and volume overload hypertrophy and inhibits collagen synthesis in cardiac fibroblasts. Journal of applied physiology (Bethesda, Md. : 1985). vol 102. issue 5. 2007-07-13. PMID:17255372. |
these pathways are implicated in the accumulation of extracellular matrix proteins during progression of hypertrophy to heart failure; however, the role of doc-2 in cardiac pathophysiology has never been examined. |
2007-07-13 |
2023-08-12 |
rat |
| Steven L Henry, Matthew J Concannon, Paul A Kaplan, Alberto A Diaz-Aria. The inhibitory effect of minocycline on hypertrophic scarring. Plastic and reconstructive surgery. vol 120. issue 1. 2007-07-10. PMID:17572548. |
matrix metalloproteinases are enzymes that serve to degrade the extracellular matrix, giving them a central role in the inflammatory and wound-healing processes; they have been implicated in the pathophysiology of hypertrophic scarring. |
2007-07-10 |
2023-08-12 |
Not clear |
| Steven L Henry, Matthew J Concannon, Paul A Kaplan, Alberto A Diaz-Aria. The inhibitory effect of minocycline on hypertrophic scarring. Plastic and reconstructive surgery. vol 120. issue 1. 2007-07-10. PMID:17572548. |
the purpose of this study was to examine the effect of minocycline, a matrix metalloproteinase inhibitor, on hypertrophic scarring. |
2007-07-10 |
2023-08-12 |
Not clear |
| S Soeta, H Shimoura, N Hatakeyama, T Kodaka, H Amasaki, S Yamano, K Taniguchi, Y Nait. Immunohistochemical examination of epiphyseal growth plates of Japanese Brown cattle with chondrodysplasia. Journal of comparative pathology. vol 136. issue 2-3. 2007-06-28. PMID:17416234. |
backscattered electron (bse) imaging showed that the calcified cartilage matrix was restricted to the lower region of the hypertrophic zone (hz) of the egp in the control cattle, while the calcified cartilage matrix and bone tissue were scattered in the inner areas of the egp in all the chondrodysplastic cattle. |
2007-06-28 |
2023-08-12 |
cattle |
| Arne Yndestad, Jan Kristian Damås, Erik Øie, Thor Ueland, Lars Gullestad, Pål Aukrus. Role of inflammation in the progression of heart failure. Current cardiology reports. vol 9. issue 3. 2007-06-19. PMID:17470337. |
importantly, experimental studies have shown that inflammatory cytokines such as tumor necrosis factor-alpha, interleukin-1b, and monocyte chemoattractant peptide-1 may contribute to the development and progression of hf by promoting myocardial hypertrophy, activating matrix metalloproteinases, provoking contractile dysfunction, and inducing apoptosis. |
2007-06-19 |
2023-08-12 |
Not clear |
| S G Vellema. Muscle development in the embryo and hatchling. Poultry science. vol 86. issue 5. 2007-06-12. PMID:17435046. |
it is probable that the expression of extracellular matrix proteins involved in growth factor signaling will affect muscle growth properties during hyperplasia and hypertrophy. |
2007-06-12 |
2023-08-12 |
Not clear |
| Cheol Whee Park, Hyeong Wook Kim, Seung Hyun Ko, Ji Hee Lim, Gyeong Ryul Ryu, Hyun Wha Chung, Sang Woo Han, Seog Jun Shin, Byung Kee Bang, Matthew D Breyer, Yoon Sik Chan. Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice. Journal of the American Society of Nephrology : JASN. vol 18. issue 4. 2007-05-31. PMID:17360951. |
renal histology studies further demonstrated that glomerular hypertrophy, mesangial matrix expansion, tgf-beta1 expression, and type iv collagen accumulation and associated glomerular lipid accumulation were significantly decreased in db/db mice that were treated with 1 nmol/kg exendin-4. |
2007-05-31 |
2023-08-12 |
mouse |
| Barbara D Boyan, Kevin L Wong, Mimi Fang, Zvi Schwart. 1alpha,25(OH)2D3 is an autocrine regulator of extracellular matrix turnover and growth factor release via ERp60 activated matrix vesicle metalloproteinases. The Journal of steroid biochemistry and molecular biology. vol 103. issue 3-5. 2007-05-11. PMID:17224270. |
during cell maturation and hypertrophy, ecm is reorganized via a process regulated by 1alpha,25(oh)(2)d(3) and involving matrix metalloproteinases (mmps), including mmp-3 and mmp-2. |
2007-05-11 |
2023-08-12 |
Not clear |
| Toni-Ann S Duhaney, Lei Cui, Mary K Rude, Nathan K Lebrasseur, Soeun Ngoy, Deepa S De Silva, Deborah A Siwik, Ronglih Liao, Flora Sa. Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload. Hypertension (Dallas, Tex. : 1979). vol 49. issue 5. 2007-05-07. PMID:17353509. |
fenofibrate also increased myocardial hypertrophy, cardiac fibrosis, and the ratio of matrix metalloproteinase-2/tissue inhibitor of matrix metalloproteinase-2 in po pparalpha-deficient mice. |
2007-05-07 |
2023-08-12 |
mouse |
| Tao Zhang, Xin-zhou Rong, Rong-hua Yang, Tian-zeng Li, Ying-bin X. [Effect of asiaticoside on the expression of transforming growth factor-beta mRNA and matrix metalloproteinases in hypertrophic scars]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 1. 2007-05-01. PMID:16495179. |
[effect of asiaticoside on the expression of transforming growth factor-beta mrna and matrix metalloproteinases in hypertrophic scars]. |
2007-05-01 |
2023-08-12 |
Not clear |
| Tao Zhang, Xin-zhou Rong, Rong-hua Yang, Tian-zeng Li, Ying-bin X. [Effect of asiaticoside on the expression of transforming growth factor-beta mRNA and matrix metalloproteinases in hypertrophic scars]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 1. 2007-05-01. PMID:16495179. |
to investigate the effect of asiaticoside on the expressions of transforming growth factor (tgf)-beta mrna, matrix metalloproteinases (mmps) and tissue inhibitors of metalloproteinases (timps) in postburn hypertrophic scars. |
2007-05-01 |
2023-08-12 |
Not clear |
| E D Fixman, A Stewart, J G Marti. Basic mechanisms of development of airway structural changes in asthma. The European respiratory journal. vol 29. issue 2. 2007-04-20. PMID:17264325. |
while information concerning the genesis of inflammation is abundant, the precise factors responsible for cellular hyperplasia, hypertrophy and altered matrix deposition are far from resolved. |
2007-04-20 |
2023-08-12 |
human |
| Ichiro Takahashi, Kazuyuki Onodera, Jin-Wan Bae, Hidetoshi Mitani, Yasuyuki Sasano, Hideo Mitan. Age-related changes in the expression of gelatinase and tissue inhibitor of metalloproteinase genes in mandibular condylar, growth plate, and articular cartilage in rats. Journal of molecular histology. vol 36. issue 5. 2007-04-17. PMID:16208432. |
therefore, we concluded that timp-1 and timp-2 were general inhibitors of mmp-2 and mmp-9 in condylar cartilage, while timp-3 regulates the collagenolytic degradation of the hypertrophic cartilage matrix. |
2007-04-17 |
2023-08-12 |
rat |
| Mei Sun, Manyin Chen, Fayez Dawood, Urszula Zurawska, Jeff Y Li, Thomas Parker, Zamaneh Kassiri, Lorrie A Kirshenbaum, Malcolm Arnold, Rama Khokha, Peter P Li. Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state. Circulation. vol 115. issue 11. 2007-04-12. PMID:17353445. |
in the present study, we tested our hypothesis that tnf-alpha regulates the cardiac inflammatory response, extracellular matrix homeostasis, and ventricular hypertrophy in response to mechanical overload and contributes to ventricular dysfunction. |
2007-04-12 |
2023-08-12 |
Not clear |
| Matthias Meier, Joon-Keun Park, Daniel Overheu, Torsten Kirsch, Carsten Lindschau, Faikah Gueler, Michael Leitges, Jan Menne, Hermann Halle. Deletion of protein kinase C-beta isoform in vivo reduces renal hypertrophy but not albuminuria in the streptozotocin-induced diabetic mouse model. Diabetes. vol 56. issue 2. 2007-04-09. PMID:17259378. |
after 8 weeks of diabetes, the high-glucose-induced renal and glomerular hypertrophy, as well as the increased expression of extracellular matrix proteins such as collagen and fibronectin, was reduced in pkc-beta(-/-) mice. |
2007-04-09 |
2023-08-12 |
mouse |