| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| H S Sharma, H A van Heugten, M A Goedbloed, P D Verdouw, J M Lamer. Angiotensin II induced expression of transcription factors precedes increase in transforming growth factor-beta 1 mRNA in neonatal cardiac fibroblasts. Biochemical and biophysical research communications vol 205 issue 1 1995 7999008 |
our results indicate that ang ii transiently stimulates the expression of transcription factors, which may up-regulate tgf-beta 1, that in turn could contribute to the process of myocardial extra-cellular matrix remodeling in hypertrophy. |
1995-01-17 |
2023-01-24 |
rat |
| T Nakase, K Takaoka, K Hirakawa, S Hirota, T Takemura, H Onoue, K Takebayashi, Y Kitamura, S Nomur. Alterations in the expression of osteonectin, osteopontin and osteocalcin mRNAs during the development of skeletal tissues in vivo. Bone and mineral vol 26 issue 2 1995 7994183 |
in growth cartilage, osn mrna was observed in chondrocytes in non-mineralized cartilage, whereas osp mrna was detected in hypertrophic chondrocytes in mineralized cartilage matrix with a characteristic switch in expression. |
1995-01-13 |
2023-01-24 |
mouse |
| J Secchi, D Lecaque, F W Dunn, S Jouquey, U D Auberval, F Benzoni, O Sirugue, G Hamo. Effects of subchronic treatment with trandolapril and enalapril on cardiovascular morphologic alterations in the aged spontaneously hypertensive rat with heart failure. Journal of cardiovascular pharmacology vol 23 Suppl 4 issue 1995 7527099 |
in the mesenteric artery, trandolapril treatment induced a complete regression of the media hypertrophy and a marked decrease in extracellular matrix surface. |
1995-01-05 |
2023-01-24 |
rat |
| H J Swa. Left ventricular dysfunction in ischemic heart disease: fundamental importance of the fibrous matrix. Cardiovascular drugs and therapy vol 8 Suppl 2 issue 1994 7947372 |
in the normal heart, and apparently in physiological hypertrophy, this matrix is submicroscopic. |
1994-12-28 |
2023-01-24 |
Not clear |
| J Suzuki, N Yoshikawa, H Nakamur. A quantitative analysis of the glomeruli in focal segmental glomerulosclerosis. Pediatric nephrology (Berlin, Germany) vol 8 issue 4 1994 7947029 |
these findings suggest that both glomerular hypertrophy and mesangial matrix increase in non-sclerotic glomeruli in fsgs may lead to glomerular sclerosis. |
1994-12-15 |
2023-01-24 |
Not clear |
| H Sakamaki, Y Kimura, M Nagum. Biological and morphological characteristics of a transplanted cartilaginous tumor derived from a human osteogenic sarcoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology vol 23 issue 7 1994 7525950 |
in the extracellular matrix around hypertrophic cells, matrix vesicles were observed with mineral deposits. |
1994-12-12 |
2023-01-24 |
mouse |
| H Sakamaki, Y Kimura, M Nagum. Biological and morphological characteristics of a transplanted cartilaginous tumor derived from a human osteogenic sarcoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology vol 23 issue 7 1994 7525950 |
alkaline phosphatase was found on the plasma membrane and golgi complexes of hypertrophic cells, and on matrix vesicles. |
1994-12-12 |
2023-01-24 |
mouse |
| M Galotto, G Campanile, G Robino, F D Cancedda, P Bianco, R Cancedd. Hypertrophic chondrocytes undergo further differentiation to osteoblast-like cells and participate in the initial bone formation in developing chick embryo. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol 9 issue 8 1994 7976506 |
in addition to staining hypertrophic chondrocytes surrounded by a type ii and type x collagen-stainable matrix, the la5 antibodies also stained elongated chondrocytes at the cartilage/bone collar interface and cells incorporated in the first layer of bone and osteoid matrix. |
1994-12-09 |
2023-01-24 |
chicken |
| R E Topping, M E Bolander, G Balia. Type X collagen in fracture callus and the effects of experimental diabetes. Clinical orthopaedics and related research vol issue 308 1994 7955687 |
an antiserum to type x collagen was prepared, and immunostaining was observed in the matrix surrounding the hypertrophic chondrocytes. |
1994-12-01 |
2023-01-24 |
rat |
| T Umehar. [Immunohistochemical localization of transforming growth factor-beta 1 in growth plate freshly transplanted into a full-thickness defect in articular cartilage]. Nihon Seikeigeka Gakkai zasshi vol 68 issue 9 1994 7525796 |
at 2 weeks after transplantation, tgf-beta 1 was detected in the matrix, but the hypertrophic chondrocyte cell membranes were not clear. |
1994-11-30 |
2023-01-24 |
rat |
| T Umehar. [Immunohistochemical localization of transforming growth factor-beta 1 in growth plate freshly transplanted into a full-thickness defect in articular cartilage]. Nihon Seikeigeka Gakkai zasshi vol 68 issue 9 1994 7525796 |
these findings suggested that tgf-beta 1 in the hypertrophic chondrocytes was probably transferred from the cytoplasm to the extracellular matrix and stimulated the ossification of the matrix with vessel induction and osteoid formation during the process of incorporation of the transplant into the articular cartilage defect. |
1994-11-30 |
2023-01-24 |
rat |
| J M Tournier, M Polette, J Hinnrasky, J Beck, Z Werb, C Basbau. Expression of gelatinase A, a mediator of extracellular matrix remodeling, by tracheal gland serous cells in culture and in vivo. The Journal of biological chemistry vol 269 issue 41 1994 7929245 |
tracheal gland morphogenesis and gland hypertrophy in disease involve the penetration of epithelial cells into the submucosa, a process that requires digestion of the basal lamina and the surrounding extracellular matrix. |
1994-11-17 |
2023-01-24 |
human |
| K Matsumoto, S Matsunaga, T Imamura, Y Ishidou, H Yoshida, T Sako. Expression and distribution of transforming growth factor-beta and decorin during fracture healing. In vivo (Athens, Greece) vol 8 issue 2 1994 7919124 |
once chondrocytes had hypertrophied, decorin was no longer observed, while the matrix around the hypertrophic chondrocytes was positively stained for tgb-beta. |
1994-11-10 |
2023-01-24 |
rat |
| A Schmitt-Gr\\xc3\\xa4ff, A Desmouli\\xc3\\xa8re, G Gabbian. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Archiv : an international journal of pathology vol 425 issue 1 1994 7921410 |
in contrast, alpha-sm actin expressing myofibroblasts persist in hypertrophic scars and in fibrotic lesions of many organs, including stroma reaction to epithelial tumours, where they are allegedly involved in retractile phenomena as well as in extracellular matrix accumulation. |
1994-11-10 |
2023-01-24 |
rat |
| C W Yang, H Vlassara, E P Peten, C J He, G E Striker, L J Strike. Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease. Proceedings of the National Academy of Sciences of the United States of America vol 91 issue 20 1994 7937785 |
we found that age induced an increase in glomerular extracellular matrix alpha 1(iv) collagen, laminin b1, and transforming growth factor beta 1 mrna levels, as measured by competitive pcr, as well as glomerular hypertrophy. |
1994-10-27 |
2023-01-24 |
mouse |
| L Schaefer, R M Schaefer, H Ling, M Teschner, A Heidlan. Renal proteinases and kidney hypertrophy in experimental diabetes. Diabetologia vol 37 issue 6 1994 7926340 |
iddm is associated with an increase in kidney size, which is due to cellular hypertrophy and progressive matrix accumulation within the glomerulus and throughout the tubulo-interstitium. |
1994-10-25 |
2023-01-24 |
rat |
| H Sakiyama, N Inaba, T Toyoguchi, Y Okada, M Matsumoto, H Moriya, H Ohts. Immunolocalization of complement C1s and matrix metalloproteinase 9 (92kDa gelatinase/type IV collagenase) in the primary ossification center of the human femur. Cell and tissue research vol 277 issue 2 1994 8082118 |
matrix metalloproteinase 9 (mmp-9, 92kda gelatinase/type iv collagenase) was also immunolocalized in hypertrophic chondrocytes, mesenchymal cells in the primitive bone marrow and the cartilage matrix adjacent to the marrow. |
1994-10-11 |
2023-01-24 |
human |
| S C Dieudonn\\xc3\\xa9, C M Semeins, S W Goei, S Vukicevic, J K Nulend, T K Sampath, M Helder, E H Burge. Opposite effects of osteogenic protein and transforming growth factor beta on chondrogenesis in cultured long bone rudiments. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol 9 issue 6 1994 8079653 |
in the ossifying center of the bone rudiments, both op-1 and tgf-beta inhibited cartilage hypertrophy, growth of the bone collar, and matrix mineralization. |
1994-10-06 |
2023-01-24 |
mouse |
| T A Sullivan, B Uschmann, R Hough, P S Lebo. Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. The Journal of biological chemistry vol 269 issue 36 1994 8077198 |
during development and fracture repair, endochondral bone formation is preceded by an orderly process of chondrocyte hypertrophy and cartilage matrix calcification. |
1994-10-04 |
2023-01-24 |
chicken |
| T A Sullivan, B Uschmann, R Hough, P S Lebo. Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. The Journal of biological chemistry vol 269 issue 36 1994 8077198 |
these results indicate that the ability of ascorbate to induce chondrocyte hypertrophy does not depend on production of a collagen-rich matrix. |
1994-10-04 |
2023-01-24 |
chicken |