| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Younai, G Venters, S Vu, L Nichter, M E Nimni, T L Tua. Role of growth factors in scar contraction: an in vitro analysis. Annals of plastic surgery. vol 36. issue 5. 1996-10-23. PMID:8743660. |
hypertrophic scar fibroblasts showed a consistently higher basal level of fibrin matrix gel (fmg) contraction than other fibroblasts. |
1996-10-23 |
2023-08-12 |
Not clear |
| M S Hirsch, S C Cook, R Killiany, K K Hartford Svobod. Increased cell diameter precedes chondrocyte terminal differentiation, whereas cell-matrix attachment complex proteins appear constant. The Anatomical record. vol 244. issue 3. 1996-10-21. PMID:8742695. |
cephalic chondrocytes become hypertrophic and secrete type x collagen into the extracellular matrix, whereas middle and caudal chondrocytes remain cartilagenous throughout development, continuing to secrete collagen types ii, ix, and xi. |
1996-10-21 |
2023-08-12 |
chicken |
| D W Haas, M F Holic. Enhanced osteonectin expression in the chondroid matrix of the unloaded mandibular condyle. Calcified tissue international. vol 59. issue 3. 1996-10-15. PMID:8694898. |
microscopic inspection of the condyle demonstrated osteonectin immunostaining of proliferating, early hypertrophic chondrocytes, and the chondroid matrix across the sagittal section in an anterior-posterior direction. |
1996-10-15 |
2023-08-12 |
mouse |
| K Imanaka-Yoshida, B A Danowski, J M Sanger, J W Sange. Living adult rat cardiomyocytes in culture: evidence for dissociation of costameric distribution of vinculin from costameric distributions of attachments. Cell motility and the cytoskeleton. vol 33. issue 4. 1996-10-03. PMID:8801032. |
we speculate that the ability of the vinculin-attached z-lines of adult cardiomyocytes to dissociate from the extracellular matrix may aid in the remodeling of the adult heart in the repair process after myocardial infarction and also in stress induced hypertrophic growth. |
1996-10-03 |
2023-08-12 |
rat |
| M E Robbins, S M Bonsi. Radiation nephropathy: a review. Scanning microscopy. vol 9. issue 2. 1996-10-02. PMID:8714748. |
the endothelial changes appear to resolve, but the mesangial lesions progress, with hypercellularity and/or hypertrophy, increased mesangial matrix, mesangial sclerosis, and ultimately, glomerulosclerosis. |
1996-10-02 |
2023-08-12 |
Not clear |
| S Na. Immunohistochemical localization of extracellular matrix proteins in cerebral vessels in chronic hypertension. Journal of neuropathology and experimental neurology. vol 55. issue 3. 1996-09-20. PMID:8786397. |
vascular hypertrophy or vascular remodeling are both associated with an increase in the extracellular matrix of cerebral arteries and arterioles in chronic hypertension. |
1996-09-20 |
2023-08-12 |
rat |
| P Grellier, M Sabbah, B Fouqueray, K Woodruff, D Yee, H E Abboud, S L Abbou. Characterization of insulin-like growth factor binding proteins and regulation of IGFBP3 in human mesangial cells. Kidney international. vol 49. issue 4. 1996-08-29. PMID:8691727. |
since igf-i and tgf-beta are implicated in glomerular hypertrophy and matrix expansion, we tested their effect on igfbps released by mc. |
1996-08-29 |
2023-08-12 |
human |
| B Maisc. Ventricular remodeling. Cardiology. vol 87 Suppl 1. 1996-08-16. PMID:8681317. |
despite the varying etiopathology that these different aspects of heart disease share, a similar sequence of molecular, biochemical and mechanical events that can lead to heart failure, myocyte hypertrophy, extensive extracellular matrix production and fibrosis, even in patients who were previously unaffected by the original disease process (for example, inflammation or infarction). |
1996-08-16 |
2023-08-12 |
Not clear |
| R Hirschber. Insulin-like growth factor I in the kidney. Mineral and electrolyte metabolism. vol 22. issue 1-3. 1996-08-12. PMID:8676803. |
igf-i has been associated with the initiation of hypertrophy in models of compensatory renal growth and may contribute to the accumulation of extracellular matrix proteins in the nephron in chronic renal diseases. |
1996-08-12 |
2023-08-12 |
Not clear |
| A Heidland, H Ling, S Vamvakas, L Pacze. Impaired proteolytic activity as a potential cause of progressive renal disease. Mineral and electrolyte metabolism. vol 22. issue 1-3. 1996-08-12. PMID:8676810. |
renal hypertrophy (an increase in cellular protein content and cellularity as well as an accumulation of extracellular matrix) is due to the imbalance between protein synthesis and degradation. |
1996-08-12 |
2023-08-12 |
Not clear |
| L Schaefer, K Meier, C Häfner, M Teschner, A Heidland, R M Schaefe. Protein restriction influences glomerular matrix turnover and tubular hypertrophy by modulation of renal proteinase activities. Mineral and electrolyte metabolism. vol 22. issue 1-3. 1996-08-12. PMID:8676812. |
protein restriction influences glomerular matrix turnover and tubular hypertrophy by modulation of renal proteinase activities. |
1996-08-12 |
2023-08-12 |
rat |
| A Cobo, E Carbajo, F Santos, E García, J M Lópe. Morphometry of uremic rat growth plate. Mineral and electrolyte metabolism. vol 22. issue 1-3. 1996-08-12. PMID:8676817. |
this is consistent with an abnormal metabolism of condrocytes as shown by a lower mean area of extracellular matrix (ema) per cell in the hypertrophic zone of the nx rats (0.23 vs. 0.58 microns 2). |
1996-08-12 |
2023-08-12 |
rat |
| M Alini, A Marriott, T Chen, S Abe, A R Pool. A novel angiogenic molecule produced at the time of chondrocyte hypertrophy during endochondral bone formation. Developmental biology. vol 176. issue 1. 1996-07-31. PMID:8654888. |
when cultured these cells produce an extensive extracellular matrix and the prehypertrophic cells mature to express the hypertrophic phenotype defined by the synthesis of type x collagen and matrix calcification. |
1996-07-31 |
2023-08-12 |
rabbit |
| A Ghahary, Y J Shen, B Nedelec, R Wang, P G Scott, E E Tredge. Collagenase production is lower in post-burn hypertrophic scar fibroblasts than in normal fibroblasts and is reduced by insulin-like growth factor-1. The Journal of investigative dermatology. vol 106. issue 3. 1996-07-25. PMID:8648180. |
we recently demonstrated that the accumulation of extracellular matrix in post-burn hypertrophic scarring (hsc) tissues is, in part, caused by an overexpression of mrna for fibronectin, type i, and type iii procollagen. |
1996-07-25 |
2023-08-12 |
Not clear |
| T Ogawa, W Linz, M Stevenson, B G Bruneau, M L Kuroski de Bold, J H Chen, H Eid, B A Schölkens, A J de Bol. Evidence for load-dependent and load-independent determinants of cardiac natriuretic peptide production. Circulation. vol 93. issue 11. 1996-07-17. PMID:8640983. |
myosin heavy chain (mhc) isoform switch was studied as an indicator of ventricular cardiocyte hypertrophy as well as the levels of collagen iii mrna as a measure of changes in extracellular matrix. |
1996-07-17 |
2023-08-12 |
rat |
| K Sharma, Y Jin, J Guo, F N Ziyade. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes. vol 45. issue 4. 1996-05-13. PMID:8603776. |
neutralization of tgf-beta by anti-tgf-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in stz-induced diabetic mice. |
1996-05-13 |
2023-08-12 |
mouse |
| K Sharma, Y Jin, J Guo, F N Ziyade. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes. vol 45. issue 4. 1996-05-13. PMID:8603776. |
diabetic nephropathy is characterized by renal hypertrophy, thickening of basement membranes, and accumulation of extracellular matrix in the glomerular mesangium and the interstitium. |
1996-05-13 |
2023-08-12 |
mouse |
| K Sharma, Y Jin, J Guo, F N Ziyade. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes. vol 45. issue 4. 1996-05-13. PMID:8603776. |
this is the first demonstration that the early characteristic features of diabetic renal involvement, which include hypertrophy and increased matrix mrnas, are largely mediated by increased endogenous tgf-beta activity in the kidney and that they can be significantly attenuated by treatment with neutralizing anti-tgf-beta antibodies. |
1996-05-13 |
2023-08-12 |
mouse |
| K Thompson, M Rabinovitc. Exogenous leukocyte and endogenous elastases can mediate mitogenic activity in pulmonary artery smooth muscle cells by release of extracellular-matrix bound basic fibroblast growth factor. Journal of cellular physiology. vol 166. issue 3. 1996-05-02. PMID:8600153. |
there is increasing evidence that extracellular matrix (ecm)-degrading proteinases contribute to the process of medial hypertrophy and neointimal proliferation in pulmonary vascular diseases. |
1996-05-02 |
2023-08-12 |
human |
| H K Gahunia, P Babyn, C Lemaire, M J Kessler, K P Pritzke. Osteoarthritis staging: comparison between magnetic resonance imaging, gross pathology and histopathology in the rhesus macaque. Osteoarthritis and cartilage. vol 3. issue 3. 1996-03-21. PMID:8581746. |
however, at this time, while mri is sensitive for detecting oa change it cannot distinguish between certain lesions such as superficial cartilage matrix fibrillation and hypertrophy both of which show elevated signal intensity. |
1996-03-21 |
2023-08-12 |
monkey |