| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michiaki Nagai, Keigo Dote, Sungha Park, Yuda Turana, Peera Buranakitjaroen, Hao-Min Cheng, Arieska Ann Soenarta, Yan Li, Kazuomi Kari. Obstructive sleep apnea and non-dipper: epiphenomena or risks of Alzheimer's disease?: a review from the HOPE Asia Network. Hypertension research : official journal of the Japanese Society of Hypertension. 2023-10-24. PMID:37875673. |
to date, few studies have evaluated the relationships of nocturnal bp dipping patterns and osa in relation to neurodegenerative diseases, particularly alzheimer's disease (ad). |
2023-10-24 |
2023-11-08 |
Not clear |
| Julian Keil, Hanni Kiiski, Liam Doherty, Victor Hernandez-Urbina, Chrystalleni Vassiliou, Camin Dean, Markus Müschenich, Hamed Bahman. Artificial sharp-wave-ripples to support memory and counter neurodegeneration. Brain research. 2023-10-23. PMID:37871674. |
in neurodegenerative diseases like alzheimer's disease, different neuropathological processes impair normal neural functioning and neural synchronization as well as sharp-wave-ripples, which impairs consolidation and retrieval of information, and compromises memory. |
2023-10-23 |
2023-11-08 |
Not clear |
| Ester Piovesana, Claudia Magrin, Matteo Ciccaldo, Martina Sola, Manolo Bellotto, Maurizio Molinari, Stéphanie Papin, Paolo Paganett. Tau accumulation in degradative organelles is associated to lysosomal stress. Scientific reports. vol 13. issue 1. 2023-10-21. PMID:37865674. |
considering the presence of tau lesions in parkinson's disease as well as in multiple neurodegenerative disorders including alzheimer's disease, our data call for further studies on strategies to alleviate alp dysfunction as new therapeutic opportunity for neurodegenerative diseases and lsd. |
2023-10-21 |
2023-11-08 |
human |
| Sumit Kumar, Amol Mahajan, Ramesh Ambatwar, Gopal Khati. Recent Advancements in the Treatment of Alzheimer's Disease: A Multitarget-directed Ligand Approach. Current medicinal chemistry. 2023-10-20. PMID:37861025. |
we aimed to find the key role and progress of mtdls in treating ad; thus, we searched for the past ten years of literature on "pub- med", "sciencedirect", "acs" and "bentham science" using the keywords neurodegenerative diseases, alzheimer's disease, and multitarget-directed ligands. |
2023-10-20 |
2023-11-08 |
Not clear |
| R M Aljarar. Neuroprotective effects of a combination of Boswellia papyrifera and Syzygium aromaticum on AlCl3 induced Alzheimer's disease in male albino rat. Brazilian journal of biology = Revista brasleira de biologia. vol 83. 2023-10-20. PMID:37851769. |
alzheimer's disease (ad) is the most common neurodegenerative disease characterized by hippocampal, and cortical neuron deterioration, oxidative stress, and severe cognitive dysfunction. |
2023-10-20 |
2023-11-08 |
rat |
| Ahmed F Abdel-Magi. The Potential of NOD-like Receptor Protein 3 Inflammasome Inhibitors in the Treatments of Diseases. ACS medicinal chemistry letters. vol 14. issue 10. 2023-10-18. PMID:37849533. |
these compounds are inhibitors of the nod-like receptor protein 3 (nlrp3) inflammasome pathway and may potentially provide a useful treatment for one or more of the diseases and disorders mediated by nlrp3, including but not limited to immune diseases, inflammatory diseases, autoimmune diseases, autoinflammatory fever syndromes, cryopyrin-associated periodic syndrome, chronic liver disease, kidney-related disease, hyperoxaluria, lupus nephritis, type i and type ii diabetes, nephropathy, neurodegenerative diseases, alzheimer's disease, cardiovascular diseases, metabolic diseases and many more. |
2023-10-18 |
2023-11-08 |
Not clear |
| Maxim L Bychkov, Aizek B Isaev, Alexander A Andreev-Andrievskiy, Konstantin Petrov, Alexander S Paramonov, Mikhail P Kirpichnikov, Ekaterina N Lyukmanov. Aβ1-42 Accumulation Accompanies Changed Expression of Ly6/uPAR Proteins, Dysregulation of the Cholinergic System, and Degeneration of Astrocytes in the Cerebellum of Mouse Model of Early Alzheimer Disease. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834299. |
alzheimer disease (ad) is a widespread neurodegenerative disease characterized by the accumulation of oligomeric toxic forms of β-amyloid (aβ1-42) and dysfunction of the cholinergic system in the different brain regions. |
2023-10-14 |
2023-10-15 |
mouse |
| Jiaxin Hu, Wenchi Sha, Shuangshuang Yuan, Jiarui Wu, Yunpeng Huan. Aggregation, Transmission, and Toxicity of the Microtubule-Associated Protein Tau: A Complex Comprehension. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834471. |
tau protein aggregates can be found in a number of devastating neurodegenerative diseases known as "tauopathies", such as alzheimer's disease (ad), frontotemporal dementia (ftd), corticobasal degeneration (cbd), etc. |
2023-10-14 |
2023-10-15 |
Not clear |
| Syed Jawad Ali Shah, Qianqian Zhang, Jingjing Guo, Hongli Liu, Huanxiang Liu, Jordi Villà-Freix. Identification of Aggregation Mechanism of Acetylated PHF6* and PHF6 Tau Peptides Based on Molecular Dynamics Simulations and Markov State Modeling. ACS chemical neuroscience. 2023-10-13. PMID:37830541. |
however, tau's dysfunction and accumulation in the human brain can lead to several neurodegenerative diseases, such as alzheimer's disease, down's syndrome, and frontotemporal dementia. |
2023-10-13 |
2023-10-15 |
human |
| Z Ryan Tian, Aruna Sharma, Dafin F Muresanu, Suraj Sharma, Lianyuan Feng, Zhiqiang Zhang, Cong Li, Anca D Buzoianu, José Vicente Lafuente, Ala Nozari, Per-Ove Sjöqvisst, Lars Wiklund, Hari Shanker Sharm. Nicotine neurotoxicity exacerbation following engineered Ag and Cu (50-60 nm) nanoparticles intoxication. Neuroprotection with nanowired delivery of antioxidant compound H-290/51 together with serotonin 5-HT3 receptor antagonist ondansetron. International review of neurobiology. vol 172. 2023-10-13. PMID:37833012. |
nicotine smoking triggers oxidative stress and are linked to several neurodegenerative diseases such as alzheimer's disease. |
2023-10-13 |
2023-10-15 |
Not clear |
| Yi-Ju Lee, Sin-Rong Chen, Ping-En Ko, Mon-Yuan Yang, Meng-Hsuin Yu, Chau-Jong Wang, Huei-Jane Le. Quercetin-3-O-β-d-glucuronide in the Nuciferine Leaf Polyphenol Extract Promotes Neurogenesis Involving the Upregulation of the Tropomyosin Receptor Kinase (Trk) Receptor and AKT/Phosphoinositide 3-Kinase Signaling Pathway. Journal of agricultural and food chemistry. 2023-10-11. PMID:37819167. |
the impairment of hippocampal neurogenesis in adults may lead to neurodegenerative disease, such as alzheimer's disease. |
2023-10-11 |
2023-10-15 |
human |
| Ian A Windham, Sarah Cohe. The cell biology of APOE in the brain. Trends in cell biology. 2023-10-07. PMID:37805344. |
the e4 variant of apoe is a major genetic risk factor for alzheimer's disease (ad) and a multitude of other neurodegenerative diseases, yet the molecular mechanisms by which apoe4 drives disease are still unclear. |
2023-10-07 |
2023-10-15 |
mouse |
| Ngoc-Han Thi Nguyen, Ji Hun Kim, Su-Min Lee, Byung-Kwan Cho, Yang-Hoon Kim, Jiho Mi. Inhibition of Tau Phosphorylation and Aβ Accumulation by S. cerevisiae-derived Vacuoles in LPS-Induced SH-SY5Y Cells. Journal of biotechnology. 2023-09-30. PMID:37777088. |
neurodegenerative diseases, such as alzheimer's disease (ad), are characterized by the accumulation of intracellular tau and amyloid beta (aβ) proteins, which lead to neuroinflammation and neuronal apoptosis. |
2023-09-30 |
2023-10-07 |
Not clear |
| Victor Voicu, Felix-Mircea Brehar, Corneliu Toader, Razvan-Adrian Covache-Busuioc, Antonio Daniel Corlatescu, Andrei Bordeianu, Horia Petre Costin, Bogdan-Gabriel Bratu, Luca-Andrei Glavan, Alexandru Vlad Ciure. Cannabinoids in Medicine: A Multifaceted Exploration of Types, Therapeutic Applications, and Emerging Opportunities in Neurodegenerative Diseases and Cancer Therapy. Biomolecules. vol 13. issue 9. 2023-09-28. PMID:37759788. |
special emphasis is placed on the role of cannabinoids in neurodegenerative diseases, showcasing their potential benefits in conditions such as alzheimer's disease, parkinson's disease, huntington's disease, and multiple sclerosis. |
2023-09-28 |
2023-10-07 |
human |
| Mattia Di Paolo, Francesca Corsi, Chiara Cerri, Silvia Bisti, Ilaria Piano, Claudia Gargin. A Window to the Brain: The Retina to Monitor the Progression and Efficacy of Saffron Repron Pharmaceuticals (Basel, Switzerland). vol 16. issue 9. 2023-09-28. PMID:37765115. |
a window to the brain: the retina to monitor the progression and efficacy of saffron repron a mechanism shared by most neurodegenerative diseases, like alzheimer's disease (ad) and parkinson's disease (pd), is neuroinflammation. |
2023-09-28 |
2023-10-07 |
mouse |
| Daniela-Carmen Ababei, Veronica Bild, Ioana Macadan, Alexandru Vasincu, Răzvan-Nicolae Rusu, Mihaela Blaj, Gabriela Dumitrița Stanciu, Radu-Marian Lefter, Walther Bil. Therapeutic Implications of Renin-Angiotensin System Modulators in Alzheimer's Dementia. Pharmaceutics. vol 15. issue 9. 2023-09-28. PMID:37765259. |
the renin-angiotensin system (ras) has attracted considerable interest beyond its traditional cardiovascular role due to emerging data indicating its potential involvement in neurodegenerative diseases, including alzheimer's dementia (ad). |
2023-09-28 |
2023-10-07 |
Not clear |
| Chao Gao, Jingwen Jiang, Yuyan Tan, Shengdi Che. Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. Signal transduction and targeted therapy. vol 8. issue 1. 2023-09-22. PMID:37735487. |
here we comprehensively review the biology of microglia and the roles of microglia in neurodegenerative diseases, including alzheimer's disease, parkinson's disease, multiple system atrophy, amyotrophic lateral sclerosis, frontotemporal dementia, progressive supranuclear palsy, corticobasal degeneration, dementia with lewy bodies and huntington's disease. |
2023-09-22 |
2023-10-07 |
Not clear |
| Michael R Kann, Peter J Zeiger, Sandra J Rizer, Stephanie Cosentino, Martina Aza. Virtual Assessment as a Way to Reduce Help-seeking Barriers in Older Adults With Subjective Cognitive Decline. Alzheimer disease and associated disorders. 2023-09-22. PMID:37738277. |
subjective cognitive decline (scd), a potential early marker for neurodegenerative disease such as alzheimer's disease, is common among older adults. |
2023-09-22 |
2023-10-07 |
Not clear |
| Vahid Reza Ostovan, Nahid Baberi, Majid Reza Farokhi, Leila Moezi, Fatema Pirsalami, Roksana Soukhaklari, Maryam Moosav. Cholinergic deficit induced memory retrieval impairment and hippocampal CaMKII-alpha deregulation is counteracted by sub-chronic agmatine treatment in mice. Neurological research. 2023-09-21. PMID:37733020. |
alzheimer's disease (ad) is one of the most prevalent neurodegenerative disease characterized by brain cholinergic dysfunction. |
2023-09-21 |
2023-10-07 |
mouse |
| Gulam Mustafa Hasan, Anas Shamsi, Sukhwinder Singh Sohal, Manzar Alam, Md Imtaiyaz Hassa. Structure-Based Identification of Natural Compounds as Potential RET-Kinase Inhibitors for Therapeutic Targeting of Neurodegenerative Diseases. Journal of Alzheimer's disease : JAD. 2023-09-18. PMID:37718821. |
tyrosine-protein kinase receptor ret (ret), a proto-oncogene, is considered as an attractive drug target for cancer and neurodegenerative diseases, including alzheimer's disease (ad). |
2023-09-18 |
2023-10-07 |
Not clear |