| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariola Zapater-Fajarí, Patricia Diaz-Galvan, Nira Cedres, Therese Rydberg Sterner, Lina Rydén, Simona Sacuiu, Margda Waern, Anna Zettergren, Henrik Zetterberg, Kaj Blennow, Silke Kern, Vanesa Hidalgo, Alicia Salvador, Eric Westman, Ingmar Skoog, Daniel Ferreir. Biomarkers of Alzheimer's disease and cerebrovascular disease in relation to depressive symptomatology in individuals with subjective cognitive decline. The journals of gerontology. Series A, Biological sciences and medical sciences. 2023-09-14. PMID:37708068. |
subjective cognitive decline (scd) has gained recent interest as a potential harbinger of neurodegenerative diseases such as alzheimer's disease (ad) and cerebrovascular disease (cvd). |
2023-09-14 |
2023-10-07 |
Not clear |
| Katsura Takano-Kawabe, Kazuyuki Matoba, Yoichi Nakamura, Mitsuaki Moriyam. Low Density Lipoprotein Receptor-related Protein 2 Expression and Function in Cultured Astrocytes and Microglia. Neurochemical research. 2023-09-13. PMID:37702891. |
activation of glial cells, astrocytes and microglia, has been observed in neurodegenerative diseases including alzheimer's disease (ad). |
2023-09-13 |
2023-10-07 |
mouse |
| Xinyi Zhao, Wen Zeng, Hong Xu, Zihan Sun, Yingxin Hu, Beibei Peng, Jennifer D McBride, Jiangtao Duan, Juan Deng, Bin Zhang, Soo-Jung Kim, Bryan Zoll, Takashi Saito, Hiroki Sasaguri, Takaomi C Saido, Carlo Ballatore, Haishan Yao, Zhaoyin Wang, John Q Trojanowski, Kurt R Brunden, Virginia M-Y Lee, Zhuohao H. A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury. Science translational medicine. vol 15. issue 713. 2023-09-13. PMID:37703352. |
tau pathogenesis is a hallmark of many neurodegenerative diseases, including alzheimer's disease (ad). |
2023-09-13 |
2023-10-07 |
mouse |
| Noemi Sola-Sevilla, Alberto Mesa-Lombardo, Mikel Aleixo, Sara Expósito, Teresa Diaz-Perdigón, Amaya Azqueta, Farzad Zamani, Takayoshi Suzuki, Silvia Maioli, Francesca Eroli, Anna Matton, Maria J Ramírez, Maite Solas, Rosa M Tordera, Eduardo D Martín, Elena Puert. SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer's Disease. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-09-12. PMID:37698780. |
recent studies propose sirt2 pharmacological inhibition as a therapeutic strategy for several neurodegenerative diseases including alzheimer's disease (ad). |
2023-09-12 |
2023-10-07 |
mouse |
| Skye Henderson, Madison Strait, Roxanne Fernandes, Hui Xu, James J Galligan, Greg M Swai. Ex Vivo Electrochemical Monitoring of Cholinergic Signaling in the Mouse Colon Using an Enzyme-Based Biosensor. ACS chemical neuroscience. 2023-09-08. PMID:37681686. |
cholinergic dysfunction is commonly associated with neurodegenerative diseases, including alzheimer's disease. |
2023-09-08 |
2023-10-07 |
mouse |
| Youn Young Lee, Jong In Han, Kyung Eun Lee, Sooyoung Cho, Eun Cheng Su. Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ Frontiers in pharmacology. vol 14. 2023-09-04. PMID:37663257. |
neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of aβ alzheimer's disease (ad), one of the most prevalent neurodegenerative diseases is associated with pathological autophagy-lysosomal pathway dysfunction. |
2023-09-04 |
2023-09-07 |
mouse |
| Sirui Zhou, Yancheng Zhou, Wanyu Zhong, Zhonghao Su, Zhenxia Qi. Involvement of protein L-isoaspartyl methyltransferase in the physiopathology of neurodegenerative diseases: Possible substrates associated with synaptic function. Neurochemistry international. 2023-09-01. PMID:37657764. |
synaptic dysfunction is a typical pathophysiologic change in neurodegenerative diseases (nds) such as alzheimer's disease (ad), parkinson's disease (pd), hintington's disease(hd) and amyotrophic lateral sclerosis (als), which involves protein post-translational modifications (ptms) including l-isoaspartate (l-isoasp) formed by isomerization of aspartate or deamidation of asparagine. |
2023-09-01 |
2023-09-07 |
Not clear |
| Cory M Nadel, Kristin Wucherer, Abby Oehler, Aye C Thwin, Koli Basu, Matthew D Callahan, Daniel R Southworth, Daniel A Mordes, Charles S Craik, Jason E Gestwick. Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP. bioRxiv : the preprint server for biology. 2023-08-30. PMID:37645969. |
microtubule-associated protein tau (mapt/tau) accumulates in a family of neurodegenerative diseases, including alzheimer's disease (ad). |
2023-08-30 |
2023-09-07 |
Not clear |
| Julen Goikolea, Maria Latorre-Leal, Christina Tsagkogianni, Sonja Pikkupeura, Balazs Gulyas, Angel Cedazo Minguez, Raul Loera-Valencia, Ingemar Björkhem, Patricia Rodriguez Rodriguez, Silvia Maiol. The Effects of CYP27A1 and CYP7B1 on cognitive function: two mouse models in Comparison. The Journal of steroid biochemistry and molecular biology. 2023-08-30. PMID:37648096. |
we believe that future studies on cyp7b1 and cyp27a1 will contribute to a better understanding of the pathogenic mechanisms of neurodegenerative diseases like alzheimer's disease and may lead to potential new therapeutic approaches. |
2023-08-30 |
2023-09-07 |
mouse |
| Ebenezer N Yamoah, Gabriela Pavlinkova, Bernd Fritzsc. The Development of Speaking and Singing in Infants May Play a Role in Genomics and Dementia in Humans. Brain sciences. vol 13. issue 8. 2023-08-26. PMID:37626546. |
in aging humans, the hippocampus and auditory nuclear centers are affected by neurodegenerative diseases such as alzheimer's, resulting in memory and auditory processing difficulties. |
2023-08-26 |
2023-09-07 |
Not clear |
| Tong Zhang, Nshunge Musheshe, Christina H J T M van der Veen, Helmut W Kessels, Amalia Dolga, Peter De Deyn, Ulrich Eisel, Martina Schmid. The Expression of Epac2 and GluA3 in an Alzheimer's Disease Experimental Model and Postmortem Patient Samples. Biomedicines. vol 11. issue 8. 2023-08-26. PMID:37626593. |
alzheimer's disease (ad) is one of the most prevalent neurodegenerative diseases, characterized by amyloid beta (aβ) and hyperphosphorylated tau accumulation in the brain. |
2023-08-26 |
2023-09-07 |
Not clear |
| Fukka You, Yoshiaki Harakawa, Toshikazu Yoshikawa, Haruhiko Inufus. Why Does the Antioxidant Complex Twendee X International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37629197. |
why does the antioxidant complex twendee x alzheimer's disease (ad) is a complex neurodegenerative disease characterized by cognitive and short-term memory impairments. |
2023-08-26 |
2023-09-07 |
Not clear |
| Javaria Baig, Neha Sawant, Priyanka Rawat, Arubala P Reddy, P Hemachandra Reddy, Sudhir Kshirsaga. Abnormal interaction of Rlip with mutant APP/Abeta and phosphorylated tau reduces wild-type Rlip levels and disrupt Rlip function in Alzheimer's disease. Biochimica et biophysica acta. Molecular basis of disease. 2023-08-26. PMID:37633469. |
ralbp1 (rlip) is a stress-activated protein, that plays an important role in aging and neurodegenerative diseases such as alzheimer's disease. |
2023-08-26 |
2023-09-07 |
Not clear |
| Jiyeon Lee, Julie M Dimitry, Jong Hee Song, Minsoo Son, Patrick W Sheehan, Melvin W King, G Travis Tabor, Young Ah Goo, Mitchell A Lazar, Leonard Petrucelli, Erik S Musie. Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice. Nature communications. vol 14. issue 1. 2023-08-25. PMID:37626048. |
alzheimer's disease, the most common age-related neurodegenerative disease, is characterized by tau aggregation and associated with disrupted circadian rhythms and dampened clock gene expression. |
2023-08-25 |
2023-09-07 |
mouse |
| Munire Aili, Kebing Zhou, Jun Zhan, Huaping Zheng, Feng Lu. Anti-inflammatory role of gold nanoparticles in the prevention and treatment of Alzheimer's disease. Journal of materials chemistry. B. 2023-08-24. PMID:37615596. |
alzheimer's disease (ad) is a neurodegenerative disease that causes memory and cognitive dysfunction and reduces a person's decision-making and reasoning functions. |
2023-08-24 |
2023-09-07 |
Not clear |
| Amanda Amorim Mugayar, Giovanna da Silva Guimarães, Paulo Henrique Tavares de Oliveira, Renan Lyra Miranda, Aline Araujo Dos Santo. Apoptosis in the neuroprotective effect of α7 nicotinic receptor in neurodegenerative models. Journal of neuroscience research. 2023-08-24. PMID:37615647. |
studies have demonstrated the relationship between the activation of these receptors and the reduction of neuronal or glial cell injury, by controlling apoptotic processes in different models, including neurodegenerative diseases such as alzheimer's disease. |
2023-08-24 |
2023-09-07 |
Not clear |
| Soudabeh Naderi, Fereshteh Motamedi, Hamid Gholami Pourbadie, Shahrbanoo Rafiei, Fariba Khodagholi, Nima Naderi, Mahyar Janahmad. Neuroprotective Effects of Ferrostatin and Necrostatin Against Entorhinal Amyloidopathy-Induced Electrophysiological Alterations Mediated by voltage-gated Ca Neurochemical research. 2023-08-24. PMID:37615884. |
neuroprotective effects of ferrostatin and necrostatin against entorhinal amyloidopathy-induced electrophysiological alterations mediated by voltage-gated ca alzheimer's disease (ad) is a progressive neurodegenerative disease that is the main form of dementia. |
2023-08-24 |
2023-09-07 |
Not clear |
| Guangxing Wang, Jianxin Han, Xin Meng, Seong Su Kang, Xia Liu, Yi Eve Sun, Qian Luo, Keqiang Y. Zein-Based Nanoparticles Improve the Therapeutic Efficacy of a TrkB Agonist toward Alzheimer's Disease. ACS chemical neuroscience. 2023-08-16. PMID:37583253. |
the brain-derived neurotrophic factor (bdnf)/trkb pathway plays a crucial role in neural plasticity and neuronal survival but is often deficient in neurodegenerative diseases like alzheimer's disease (ad). |
2023-08-16 |
2023-09-07 |
mouse |
| Anindita Behera, Sweta Priyadarshini Pradhan, P Tejaswani, Nishigandha Sa, Swagata Pattnaik, Pratap Kumar Sah. Ameliorative and Neuroprotective Effect of Core-Shell Type Se@Au Conjugated Hesperidin Nanoparticles in Diabetes-Induced Cognitive Impairment. Molecular neurobiology. 2023-08-10. PMID:37561235. |
hesperidin-conjugated bimetallic nanoparticles improved learning and memory in the stz rat model and may be an alternative approach for neurodegenerative diseases, including alzheimer's disease. |
2023-08-10 |
2023-08-16 |
rat |
| M A B S Akhonda, Mary E Faulkner, Zhaoyuan Gong, John P Laporte, Sarah Church, Jarod D'Agostino, Jan Bergeron, Christopher M Bergeron, Luigi Ferrucci, Mustapha Bouhrar. The effect of the human brainstem myelination on gait speed in normative aging. The journals of gerontology. Series A, Biological sciences and medical sciences. 2023-08-09. PMID:37555749. |
further studies are needed to understand the longitudinal changes in brainstem myelination with aging and neurodegenerative diseases, including alzheimer's disease and parkinson's disease. |
2023-08-09 |
2023-08-16 |
human |