| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giorgia Serena Gullotta, Giuseppe Costantino, Maria Angela Sortino, Simona Federica Spampinat. Microglia and the Blood-Brain Barrier: An External Player in Acute and Chronic Neuroinflammatory Conditions. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298096. |
here, we report the specific crosstalk of microglia with all the bbb cell types focusing in particular on the involvement of microglia in the modulation of bbb function in neuroinflammatory conditions that occur in conjunction with an acute event, such as a stroke, or in a slow neurodegenerative disease, such as alzheimer's disease. |
2023-06-11 |
2023-08-14 |
Not clear |
| Jingwen Wang, Zhiling Yu, Ye Peng, Baojun X. Insights into prevention mechanisms of bioactive components from healthy diets against Alzheimer's disease. The Journal of nutritional biochemistry. 2023-06-10. PMID:37301484. |
alzheimer's disease (ad) is a progressive neurodegenerative disease in which senile plaques, neurofibrillary tangles, insulin resistance, oxidative stress, chronic neuroinflammation, and abnormal neurotransmission are the potential mechanisms involved in its onset and development. |
2023-06-10 |
2023-08-14 |
Not clear |
| Monika Arbaciauskaite, Azady Pirhanov, Erik Ammermann, Yu Lei, Yong Ku Ch. Yeast biopanning against site-specific phosphorylations in tau. Protein engineering, design & selection : PEDS. 2023-06-09. PMID:37294629. |
the detection of site-specific phosphorylation in the microtubule-associated protein tau is emerging as a means to diagnose and monitor the progression of alzheimer's disease (ad) as well as other neurodegenerative diseases. |
2023-06-09 |
2023-08-14 |
Not clear |
| Ram Kumar Manthari, Prathyusha Koyya, Santhi Latha Pandrang. Brain-Derived Neurotrophic Factor - The Protective Agent Against Neurological Disorders. CNS & neurological disorders drug targets. 2023-06-08. PMID:37287291. |
the pathophysiology of some neurodegenerative diseases, including alzheimer's, parkinson's, schizophrenia, and huntington's, has been linked to bdnf. |
2023-06-08 |
2023-08-14 |
Not clear |
| Houfang Long, Shuyi Zeng, Yunpeng Sun, Cong Li. Biochemical and biophysical characterization of pathological aggregation of amyloid proteins. Biophysics reports. vol 8. issue 1. 2023-06-08. PMID:37287686. |
several amyloid proteins including α-synuclein (α-syn), tau, amyloid β (aβ) protein, and tar dna-binding protein 43 kda (tdp-43) form pathological fibrils and deposit in patient brains of different neurodegenerative diseases (nds) such as parkinson's disease (pd), alzheimer's disease (ad) and amyotrophic lateral sclerosis (als). |
2023-06-08 |
2023-08-14 |
human |
| Xiaodong Zhao, Mengmeng Kong, Yilin Wang, Yingxin Mao, Huilian Xu, Wenxing He, Yan He, Jinsong G. Nicotinamide mononucleotide improves the Alzheimer's disease by regulating intestinal microbiota. Biochemical and biophysical research communications. vol 670. 2023-06-04. PMID:37271037. |
alzheimer's disease (ad) is the most common progressive neurodegenerative disease, and the intestinal flora and its metabolites play an important role in the amelioration of central nervous system (cns) disorders such as ad through a bidirectional interaction between the gut-brain axis (gba). |
2023-06-04 |
2023-08-14 |
Not clear |
| Shah Alam Khan, Mohammad Jawaid Akhtar, Urvashee Gogoi, Dhanalekshmi Unnikrishnan Meenakshi, Aparoop Da. An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities. Pharmaceuticals (Basel, Switzerland). vol 16. issue 2. 2023-06-01. PMID:37259329. |
a loss or degeneration of cholinergic neurons that leads to a reduction in ach levels is considered a significant contributing factor in the development of neurodegenerative diseases (nds) such as alzheimer's disease (ad). |
2023-06-01 |
2023-08-14 |
Not clear |
| Noelle C Punessen, Claudia Pena, Alexandra Sandberg, Lilia A Koza, Daniel A Linsema. A novel anti-apoptotic role for Cdc42/ACK-1 signaling in neurons. Molecular and cellular neurosciences. 2023-06-01. PMID:37263460. |
neurodegenerative diseases such as amyotrophic lateral sclerosis, alzheimer's and parkinson's disease are caused by a progressive and aberrant destruction of neurons in the brain and spinal cord. |
2023-06-01 |
2023-08-14 |
rat |
| Nicholas B Dadario, Michael E Sughru. The functional role of the precuneus. Brain : a journal of neurology. 2023-05-31. PMID:37254740. |
together, the structural-functional connectivity of the precuneus has provided central elements which can model various neurodegenerative diseases and psychiatric disorders, such as alzheimer's disease and depression. |
2023-05-31 |
2023-08-14 |
Not clear |
| Arthur Ribeiro-Dos-Santos, Leonardo Miranda de Brito, Gilderlanio Santana de Araúj. The fusiform gyrus exhibits differential gene-gene co-expression in Alzheimer's disease. Frontiers in aging neuroscience. vol 15. 2023-05-31. PMID:37255536. |
alzheimer's disease (ad) is an irreversible neurodegenerative disease clinically characterized by the presence of β-amyloid plaques and tau deposits in various regions of the brain. |
2023-05-31 |
2023-08-14 |
Not clear |
| Lei Xia, Fan Zhang, Yulu Li, Yuemi Mo, Lingqiu Zhang, Qianhua Li, Minghuang Luo, Xiaotao Hou, Zhengcai Du, Jiagang Deng, Erwei Ha. A new perspective on Alzheimer's disease: m6A modification. Frontiers in genetics. vol 14. 2023-05-31. PMID:37255714. |
as a neurodegenerative disease, alzheimer's disease (ad) is characterized by synaptic loss, extracellular plaques of amyloid accumulation, hyperphosphorylation of tau, and neuroinflammation. |
2023-05-31 |
2023-08-14 |
Not clear |
| Camilla Christina Pedersen, Anastasia Ushakova, Ragnhild Eide Skogseth, Guido Alves, Ole-Bjørn Tysnes, Dag Aarsland, Johannes Lange, Jodi Maple-Grøde. Inflammatory Biomarkers in Newly Diagnosed Patients With Parkinson Disease and Related Neurodegenerative Disorders. Neurology(R) neuroimmunology & neuroinflammation. vol 10. issue 4. 2023-05-31. PMID:37258413. |
neuroinflammation also plays a role in related neurodegenerative diseases, such as dementia with lewy bodies (dlb) and alzheimer disease (ad). |
2023-05-31 |
2023-08-14 |
Not clear |
| Pratap G Kenchappa, Yalpi Karthik, Poornima D Vijendra, Raghavendra L S Hallur, Ajay S Khandagale, Ashok K Pandurangan, Sathisha G Jayanna, Mohammed Ali Alshehri, Abdulrahman Alasmari, Samy Sayed, Manjula Shantaram, Muntazir Mushta. Frontiers in pharmacology. vol 14. 2023-05-26. PMID:37234712. |
alzheimer's disease (ad) is a type of neurodegenerative disease, associated with the hastening of ros, acetylcholinesterase (ache) activity, and amyloid β peptides plaques in the brain. |
2023-05-26 |
2023-08-14 |
Not clear |
| Jingshan Chen, Xue Zhao, Wenyan Zhang, Tianxiang Zhang, Siting Wu, Jinghao Shao, Fu-Dong Sh. Reference intervals for plasma amyloid-β, total tau, and phosphorylated tau181 in healthy elderly Chinese individuals without cognitive impairment. Alzheimer's research & therapy. vol 15. issue 1. 2023-05-26. PMID:37237388. |
plasma amyloid-β (aβ) peptides and tau proteins are promising biomarkers of alzheimer's disease (ad), not only for predicting aβ and tau pathology but also for differentiating ad from other neurodegenerative diseases. |
2023-05-26 |
2023-08-14 |
Not clear |
| Junjie He, Yunsong Peng, Bangkang Fu, Yuemin Zhu, Lihui Wang, Rongpin Wan. msQSM: Morphology-based Self-supervised Deep Learning for Quantitative Susceptibility Mapping. NeuroImage. 2023-05-23. PMID:37220799. |
research on applications in neurodegenerative diseases found that our method is robust enough to measure significant increase in striatal magnetic susceptibility in patients during alzheimer's disease progression, as well as significant increase in substantia nigra susceptibility in parkinson's disease patients, and can be used as an auxiliary differential diagnosis tool for alzheimer's disease and parkinson's disease. |
2023-05-23 |
2023-08-14 |
human |
| Sareh Kakavandi, Iman Zare, Maryam VaezJalali, Masoud Dadashi, Maryam Azarian, Abdullatif Akbari, Marzieh Ramezani Farani, Hamidreza Zalpoor, Bahareh Hajikhan. Structural and non-structural proteins in SARS-CoV-2: potential aspects to COVID-19 treatment or prevention of progression of related diseases. Cell communication and signaling : CCS. vol 21. issue 1. 2023-05-15. PMID:37189112. |
in addition, sars-cov-2 can stimulate pathological intracellular signaling pathways by triggering transcription factor hypoxia-inducible factor-1 (hif-1), neuropilin-1 (nrp-1), cd147, and eph receptors, which play important roles in the progression of neurodegenerative diseases like alzheimer's disease, epilepsy, and multiple sclerosis, and multiple cancers such as glioblastoma, lung malignancies, and leukemias. |
2023-05-15 |
2023-08-14 |
human |
| Matilda Iemmolo, Giulio Ghersi, Giulia Bivon. The Cytokine CX3CL1 and ADAMs/MMPs in Concerted Cross-Talk Influencing Neurodegenerative Diseases. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175729. |
in this review, the dual roles of cx3cl1 and adams/mmps in different neurodegenerative diseases, such as alzheimer's disease (ad), parkinson's disease (pd), huntington's disease (mh), and multiple sclerosis (ms), are investigated. |
2023-05-14 |
2023-08-14 |
Not clear |
| Yuxing Xia, Brach M Bell, Benoit I Giasso. Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175990. |
alzheimer's disease (ad) and frontotemporal dementia (ftd) can be classified as tauopathies, which are a group of neurodegenerative diseases that develop toxic tau aggregates in specific brain regions. |
2023-05-14 |
2023-08-14 |
Not clear |
| Zahra Gholami Mahmoudian, Ali Ghanbari, Iraj Rashidi, Iraj Amiri, Alireza Komak. Minocycline effects on memory and learning impairment in the beta-amyloid-induced Alzheimer's disease model in male rats using behavioral, biochemical, and histological methods. European journal of pharmacology. 2023-05-13. PMID:37179042. |
alzheimer's disease (ad), as an advanced neurodegenerative disease, is characterized by the everlasting impairment of memory, which is determined by hyperphosphorylation of intracellular tau protein and accumulation of beta-amyloid (aβ) in the extracellular space. |
2023-05-13 |
2023-08-14 |
rat |
| S L Fowler, T S Behr, E Turkes, P Maglio Cauhy, M S Foiani, A Schaler, G Crowley, S Bez, E Ficulle, E Tsefou, D P O'Brien, R Fischer, B Geary, P Gaur, C Miller, P D'Acunzo, E Levy, K E Duff, B Ryskeldi-Falco. Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease. bioRxiv : the preprint server for biology. 2023-05-10. PMID:37163117. |
the abnormal assembly of tau protein in neurons is the pathological hallmark of multiple neurodegenerative diseases, including alzheimer's disease (ad). |
2023-05-10 |
2023-08-14 |
Not clear |