| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manuel Flores-Leon, Tiago Fleming Outeir. More than meets the eye in Parkinson's disease and other synucleinopathies: from proteinopathy to lipidopathy. Acta neuropathologica. 2023-07-08. PMID:37421475. |
the accumulation of proteinaceous inclusions in the brain is a common feature among neurodegenerative diseases such as alzheimer's disease, parkinson's disease (pd), and dementia with lewy bodies (dlb). |
2023-07-08 |
2023-08-14 |
Not clear |
| Gavin T Kress, Emily S Popa, Paul M Thompson, Susan Y Bookheimer, Sophia I Thomopoulos, Christopher R K Ching, Hong Zheng, Daniel A Hirsh, David A Merrill, Stella E Panos, Cyrus A Raji, Prabha Siddarth, Jennifer E Brame. Preliminary validation of a structural magnetic resonance imaging metric for tracking dementia-related neurodegeneration and future decline. NeuroImage. Clinical. vol 39. 2023-07-08. PMID:37421927. |
alzheimer's disease (ad) is a progressive neurodegenerative disease characterized by cognitive decline and atrophy in the medial temporal lobe (mtl) and subsequent brain regions. |
2023-07-08 |
2023-08-14 |
Not clear |
| Wanran Li, Yun Zhen. MicroRNAs in Extracellular Vesicles of Alzheimer's Disease. Cells. vol 12. issue 10. 2023-07-06. PMID:37408212. |
alzheimer's disease (ad) is a neurodegenerative disease with dysfunction of memory, language and thinking. |
2023-07-06 |
2023-08-14 |
mouse |
| Federica Sorrentino, Chiara Fenoglio, Luca Sacchi, Maria Serpente, Andrea Arighi, Tiziana Carandini, Beatrice Arosio, Evelyn Ferri, Marina Arcaro, Caterina Visconte, Emanuela Rotondo, Elio Scarpini, Daniela Galimbert. Klotho Gene Expression Is Decreased in Peripheral Blood Mononuclear Cells in Patients with Alzheimer's Disease and Frontotemporal Dementia. Journal of Alzheimer's disease : JAD. 2023-07-02. PMID:37393504. |
the longevity gene klotho (kl) was recently associated with neurodegenerative diseases including alzheimer's disease (ad). |
2023-07-02 |
2023-08-14 |
Not clear |
| Jasvinder Singh Bhatti, Satinder Kaur, Jayapriya Mishra, Harikrishnareddy Dibbanti, Arti Singh, Arubala P Reddy, Gurjit Kaur Bhatti, P Hemachandra Redd. Targeting dynamin-related protein-1 as a potential therapeutic approach for mitochondrial dysfunction in Alzheimer's disease. Biochimica et biophysica acta. Molecular basis of disease. 2023-07-01. PMID:37392948. |
alzheimer's disease (ad) is a neurodegenerative disease that manifests its pathology through synaptic damage, mitochondrial abnormalities, microrna deregulation, hormonal imbalance, increased astrocytes & microglia, accumulation of amyloid β (aβ) and phosphorylated tau in the brains of ad patients. |
2023-07-01 |
2023-08-14 |
Not clear |
| Wael Mohamed, Jaya Kumar, Badrah S Alghamdi, Al-Hassan Soliman, Yamashita Toshihid. Neurodegeneration and inflammation crosstalk: Therapeutic targets and perspectives. IBRO neuroscience reports. vol 14. 2023-06-30. PMID:37388502. |
alzheimer's, als, parkinson's, frontotemporal dementia (ftd), and epilepsy are a few of the neurodegenerative diseases that have been linked to microglia and astroglia cells, in particular. |
2023-06-30 |
2023-08-14 |
Not clear |
| Mohammad Javad Sedghizadeh, Hamid Aghajan, Zahra Vahab. Brain electrophysiological recording during olfactory stimulation in mild cognitive impairment and Alzheimer disease patients: An EEG dataset. Data in brief. vol 48. 2023-06-29. PMID:37383823. |
olfactory dysfunction has been shown to be associated with neurodegenerative diseases such as dementia and alzheimer's disease. |
2023-06-29 |
2023-08-14 |
human |
| P Hemachandra Reddy, Sudhir Kshirsagar, Chhanda Bose, Jangampalli Adi Pradeepkiran, Ashly Hindle, Sharda P Singh, Arubala P Reddy, Javaria Bai. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells. vol 12. issue 12. 2023-06-28. PMID:37371116. |
ralbp1 (rlip) is a stress-activated protein that is believed to play a large role in aging and neurodegenerative diseases such as alzheimer's disease (ad) and other tauopathies. |
2023-06-28 |
2023-08-14 |
Not clear |
| Andrea Flores, Paula Moyano, Emma Sola, José Manuel García, Jimena García, María Teresa Frejo, Lucia Guerra-Menéndez, Elena Labajo, Inés Lobo, Luisa Abascal, Javier Del Pin. Bisphenol-A Neurotoxic Effects on Basal Forebrain Cholinergic Neurons In Vitro and In Vivo. Biology. vol 12. issue 6. 2023-06-28. PMID:37372067. |
basal forebrain cholinergic neurons (bfcn) regulate memory and learning processes and their selective loss, as observed in alzheimer's disease and other neurodegenerative diseases, leads to cognitive decline. |
2023-06-28 |
2023-08-14 |
rat |
| Sangram Nag, Ryosuke Arakawa, Zhisheng Jia, Erik Lachapelle, Lei Zhang, Kevin Maresca, Laigao Chen, Mahabuba Jahan, Timothy Mccarthy, Christer Halldi. Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP). Molecules (Basel, Switzerland). vol 28. issue 12. 2023-06-28. PMID:37375167. |
muscarinic acetylcholine receptors (machr), including m4, draw attention as therapeutic targets for several neurodegenerative diseases including alzheimer's disease (ad). |
2023-06-28 |
2023-08-14 |
Not clear |
| Jinhua Li, Yarong Wu, Shuze Dong, Ye Yu, Yuhao Wu, Benhan Xiang, Qin L. Research Progress on Neuroprotective Effects of Isoquinoline Alkaloids. Molecules (Basel, Switzerland). vol 28. issue 12. 2023-06-28. PMID:37375352. |
neuronal injury and apoptosis are important causes of the occurrence and development of many neurodegenerative diseases, such as cerebral ischemia, alzheimer's disease, and parkinson's disease. |
2023-06-28 |
2023-08-14 |
Not clear |
| Juciano Gasparotto, Nauana Somensi, Carolina Saibro Girardi, Reykla Ramon Bittencourt, Laura Martinewski de Oliveira, Laura Piloneto Hoefel, Ingrid Matsubara Scheibel, Daniel Oppermann Peixoto, José Claudio Fonseca Moreira, Tiago Fleming Outeiro, Daniel Pens Gelai. Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease. Journal of neurochemistry. 2023-06-28. PMID:37381043. |
as chronic inflammation is consistently present in neurodegenerative diseases, it was largely assumed that rage could act as a critical modulator of neuroinflammation in parkinson's disease (pd), similar to what was reported for alzheimer's disease (ad), where rage is postulated to mediate pro-inflammatory signaling in microglia by binding to amyloid-β peptide. |
2023-06-28 |
2023-08-14 |
Not clear |
| Lan Xiao, Xuyu Yang, Vinay Kumar Sharma, Daniel Abebe, Y Peng Lo. Hippocampal delivery of neurotrophic factor-α1/carboxypeptidase E gene prevents neurodegeneration, amyloidosis, memory loss in Alzheimer's Disease male mice. Molecular psychiatry. 2023-06-27. PMID:37369719. |
alzheimer's disease (ad) is a prevalent neurodegenerative disease characterized by tau hyperphosphorylation, aβ1-42 aggregation and cognitive dysfunction. |
2023-06-27 |
2023-08-14 |
mouse |
| Jonathan Godinez, Catherine Y Lee, Jason P Schwan. Synthesis and Evaluation of Fmoc-Amino Esters and Amides Bearing a Substrate Like Quaternary Ammonium Group as Selective Butyrylcholinesterase Inhibitors. Bioorganic & medicinal chemistry letters. 2023-06-26. PMID:37364726. |
the depletion of the neurotransmitter acetylcholine has been suggested to contribute to the reduced cognitive function observed in individuals suffering from neurodegenerative diseases such as alzheimer's disease (ad). |
2023-06-26 |
2023-08-14 |
Not clear |
| Linda G Yang, Zachary M March, Roxan A Stephenson, Priyanka S Naraya. Apolipoprotein E in lipid metabolism and neurodegenerative disease. Trends in endocrinology and metabolism: TEM. 2023-06-25. PMID:37357100. |
variants of the lipid transport protein, apolipoprotein e (apoe), modulate risk and resilience in several neurodegenerative diseases including late-onset alzheimer's disease (load). |
2023-06-25 |
2023-08-14 |
Not clear |
| In Soo Ryu, Dae Hoon Kim, Ju-Ye Ro, Byeong-Gyu Park, Seo Hyun Kim, Jong-Yeop Im, Jun-Young Lee, Soo Jin Yoon, Heeyoung Kang, Takeshi Iwatsubo, Charlotte E Teunissen, Hyun-Jeong Cho, Jin-Hyeob Ry. The microRNA-485-3p concentration in salivary exosome-enriched extracellular vesicles is related to amyloid β deposition in the brain of patients with Alzheimer's disease. Clinical biochemistry. 2023-06-24. PMID:37355215. |
alzheimer's disease (ad) is an irreversible neurodegenerative disease characterized by progressive long-term memory loss and cognitive dysfunction. |
2023-06-24 |
2023-08-14 |
Not clear |
| Yi Yao, Yanmin Chang, Shaomin Li, Jiahui Zhu, Yanqing Wu, Xingjun Jiang, Lulu Li, Ruitian Liu, Rong Ma, Gang L. Complement C3a Receptor Antagonist Alleviates Tau Pathology and Ameliorates Cognitive Deficits in P301S Mice. Brain research bulletin. 2023-06-17. PMID:37330021. |
human tauopathies, including alzheimer's disease (ad), are a major class of neurodegenerative diseases characterized by intracellular deposition of pathological hyperphosphorylated forms of tau protein. |
2023-06-17 |
2023-08-14 |
mouse |
| Saima Khatoon, Nida Kalam, Summya Rashid, Gulnaz Ban. Effects of gut microbiota on neurodegenerative diseases. Frontiers in aging neuroscience. vol 15. 2023-06-16. PMID:37323141. |
a progressive degradation of the brain's structure and function, which results in a reduction in cognitive and motor skills, characterizes neurodegenerative diseases (nds) such as alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis (als), and huntington's disease (hd). |
2023-06-16 |
2023-08-14 |
human |
| Xiaobo Zhang, Zhimin Li, Qian Zhang, Zegang Yin, Zhijie Lu, Yang L. A new weakly supervised deep neural network for recognizing Alzheimer's disease. Computers in biology and medicine. vol 163. 2023-06-15. PMID:37321100. |
alzheimer's disease (ad) is a chronic neurodegenerative disease that mainly affects older adults, causing memory loss and decline in thinking skills. |
2023-06-15 |
2023-08-14 |
Not clear |
| Yuxing Xia, Brach M Bell, Justin D Kim, Benoit I Giasso. Tau mutation S356T in the three repeat isoform leads to microtubule dysfunction and promotes prion-like seeded aggregation. Frontiers in neuroscience. vol 17. 2023-06-12. PMID:37304025. |
tauopathies are a group of neurodegenerative diseases, which include frontotemporal dementia (ftd) and alzheimer's disease (ad), broadly defined by the development of tau brain aggregates. |
2023-06-12 |
2023-08-14 |
Not clear |