| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhuojia Xu, Aihua Qu, Hongyu Zhang, Weiwei Wang, Changlong Hao, Meiru Lu, Baimei Shi, Liguang Xu, Maozhong Sun, Chuanlai Xu, Hua Kuan. Photoinduced elimination of senescent microglia cells Chemical science. vol 13. issue 22. 2022-06-27. PMID:35756519. |
photoinduced elimination of senescent microglia cells parkinson's disease (pd) is an age-related neurodegenerative disease, and the removal of senescent cells has been proved to be beneficial for improving age-associated pathologies in neurodegeneration disease. |
2022-06-27 |
2023-08-14 |
Not clear |
| Jae Lee, Sung Wook Kim, Kyong-Tai Ki. Region-Specific Characteristics of Astrocytes and Microglia: A Possible Involvement in Aging and Diseases. Cells. vol 11. issue 12. 2022-06-24. PMID:35741031. |
in addition, the regional heterogeneity of astrocytes and microglia exhibits different functions in several situations, such as aging and neurodegenerative diseases. |
2022-06-24 |
2023-08-14 |
Not clear |
| Jae Lee, Sung Wook Kim, Kyong-Tai Ki. Region-Specific Characteristics of Astrocytes and Microglia: A Possible Involvement in Aging and Diseases. Cells. vol 11. issue 12. 2022-06-24. PMID:35741031. |
in this review, we summarize up-to-date research on various intra- and inter-regional heterogeneities of astrocytes and microglia, and provide information on how they can be applied to aging and neurodegenerative diseases. |
2022-06-24 |
2023-08-14 |
Not clear |
| Carlos González-Fernández, Pau González, Francisco González-Pérez, Francisco Javier Rodrígue. Characterization of Ex Vivo and In Vitro Wnt Transcriptome Induced by Spinal Cord Injury in Rat Microglial Cells. Brain sciences. vol 12. issue 6. 2022-06-24. PMID:35741593. |
it is well known that inflammation is crucial in the onset and progression of neurodegenerative diseases and traumatic central nervous system (cns) injuries, and that microglia and monocyte-derived macrophages (mdms) play a pivotal role in neuroinflammation. |
2022-06-24 |
2023-08-14 |
rat |
| Darya Khantakova, Simone Brioschi, Martina Molgor. Exploring the Impact of TREM2 in Tumor-Associated Macrophages. Vaccines. vol 10. issue 6. 2022-06-24. PMID:35746551. |
trem2 has been extensively studied in microglia and neurodegenerative diseases and recently emerged as a marker of pro-tumorigenic macrophages. |
2022-06-24 |
2023-08-14 |
Not clear |
| Pedro Melo, Renato Socodato, Mariana S Silveira, Miguel António Dias Neves, João Bettencourt Relvas, Inês Mendes Pint. Mechanical actuators in microglia dynamics and function. European journal of cell biology. vol 101. issue 3. 2022-06-12. PMID:35691123. |
microglia undergo dramatic transcriptomic and shape changes upon brain insults or neurodegenerative disease states and adopt a classical immune effector function (producing an extensive array of inflammatory mediators such as cytokines, chemokines, and reactive oxygen species) to re-establish tissue homeostasis. |
2022-06-12 |
2023-08-14 |
Not clear |
| Shu Zhou, Jinjun Li, XiaoNa Zhang, Wen Xion. MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6. Bioengineered. vol 13. issue 5. 2022-06-06. PMID:35658788. |
microglia activation-stimulated neuroinflammation exerts functionally in neurodegenerative diseases like brain injury. |
2022-06-06 |
2023-08-14 |
rat |
| Qing Wang, Li-Juan Song, Zhi-Bin Ding, Zhi Chai, Jie-Zhong Yu, Bao-Guo Xiao, Cun-Gen M. Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases. Neural regeneration research. vol 17. issue 12. 2022-06-06. PMID:35662192. |
this review will systematically describe, for the first time, the effects of abnormal activation of rocks on t cells, b cells, microglia, astrocytes, oligodendrocytes, and pericytes in neurodegenerative diseases of the central nervous system, summarize the therapeutic potential of fasudil in several experimental models of neurodegenerative diseases, and clarify the possible cellular and molecular mechanisms of rocks inhibition. |
2022-06-06 |
2023-08-14 |
Not clear |
| Emmanuel Moyse, Slavica Krantic, Nesrine Djellouli, Sébastien Roger, Denis Angoulvant, Camille Debacq, Victoire Leroy, Bertrand Fougere, Amal Aidou. Neuroinflammation: A Possible Link Between Chronic Vascular Disorders and Neurodegenerative Diseases. Frontiers in aging neuroscience. vol 14. 2022-06-06. PMID:35663580. |
a comparative survey of the best-known physiological contexts of neuroinflammation (neurodegenerative diseases and transient ischemia) reveals some common features such as microglia activation. |
2022-06-06 |
2023-08-14 |
Not clear |
| Emmanuel Moyse, Slavica Krantic, Nesrine Djellouli, Sébastien Roger, Denis Angoulvant, Camille Debacq, Victoire Leroy, Bertrand Fougere, Amal Aidou. Neuroinflammation: A Possible Link Between Chronic Vascular Disorders and Neurodegenerative Diseases. Frontiers in aging neuroscience. vol 14. 2022-06-06. PMID:35663580. |
the recently published transcriptomic characterizations of microglia have pointed a marker core signature among neurodegenerative diseases, but also unraveled the discrepancies with neuroinflammations related with acute diseases of vascular origin. |
2022-06-06 |
2023-08-14 |
Not clear |
| Raghavendra Upadhya, Leelavathi N Madhu, Shama Rao, Ashok K Shett. Proficiency of Extracellular Vesicles From hiPSC-Derived Neural Stem Cells in Modulating Proinflammatory Human Microglia: Role of Pentraxin-3 and miRNA-21-5p. Frontiers in molecular neuroscience. vol 15. 2022-06-03. PMID:35656007. |
the results demonstrate that hnsc-evs are proficient for modulating the proinflammatory human microglia into non-inflammatory phenotypes, implying their utility to treat neuroinflammation in neurodegenerative diseases. |
2022-06-03 |
2023-08-14 |
mouse |
| Ana María Rodríguez, Julia Rodríguez, Guillermo Hernán Giambartolome. Microglia at the Crossroads of Pathogen-Induced Neuroinflammation. ASN neuro. vol 14. 2022-05-31. PMID:35635133. |
most of the knowledge about the harmful effects of activated microglia on cns has arisen from studies on neurodegenerative diseases. |
2022-05-31 |
2023-08-13 |
Not clear |
| Carla Cuní-López, Romal Stewart, Hazel Quek, Anthony R Whit. Recent Advances in Microglia Modelling to Address Translational Outcomes in Neurodegenerative Diseases. Cells. vol 11. issue 10. 2022-05-28. PMID:35626698. |
recent advances in microglia modelling to address translational outcomes in neurodegenerative diseases. |
2022-05-28 |
2023-08-13 |
human |
| Carla Cuní-López, Romal Stewart, Hazel Quek, Anthony R Whit. Recent Advances in Microglia Modelling to Address Translational Outcomes in Neurodegenerative Diseases. Cells. vol 11. issue 10. 2022-05-28. PMID:35626698. |
increasing evidence suggests that neuroinflammation, largely mediated by microglia, the resident immune cells of the brain, contributes to the onset and progression of neurodegenerative diseases. |
2022-05-28 |
2023-08-13 |
human |
| Carla Cuní-López, Romal Stewart, Hazel Quek, Anthony R Whit. Recent Advances in Microglia Modelling to Address Translational Outcomes in Neurodegenerative Diseases. Cells. vol 11. issue 10. 2022-05-28. PMID:35626698. |
hence, microglia are considered a major therapeutic target that could potentially yield effective disease-modifying treatments for neurodegenerative diseases. |
2022-05-28 |
2023-08-13 |
human |
| Carla Cuní-López, Romal Stewart, Hazel Quek, Anthony R Whit. Recent Advances in Microglia Modelling to Address Translational Outcomes in Neurodegenerative Diseases. Cells. vol 11. issue 10. 2022-05-28. PMID:35626698. |
here, we review the key roles of microglia in neurodegenerative diseases and provide an update on the current microglial plaforms utilised in neurodegenerative diseases, with a focus on human microglia-like cells derived from peripheral blood mononuclear cells as well as human-induced pluripotent stem cells. |
2022-05-28 |
2023-08-13 |
human |
| Ana Bruna de Araújo, Francisco Vinícius Clemente Serra Azul, Francisca Raysse Mesquita Silva, Talysson Silva de Almeida, João Victor Nunes Oliveira, Antônia Torres Ávila Pimenta, Antônio Marcos Esmeraldo Bezerra, Nuno J Machado, Luzia Kalyne Almeida Moreira Lea. Antineuroinflammatory Effect of Oxidative medicine and cellular longevity. vol 2022. 2022-05-09. PMID:35528510. |
antineuroinflammatory effect of microglia plays an important role in the neuroinflammatory response, identified as one of the major factors in the development and progression of neurodegenerative diseases. |
2022-05-09 |
2023-08-13 |
Not clear |
| Yue-Ying Liu, Tian-Shu DU, Yang Liu, Zhen Zhang, Ai-Niwaer Aizier, Xiao-Li Gong, Xiao-Min Wang, Ting Zhan. [Phagocytosis of microglia in neurodegenerative diseases]. Sheng li xue bao : [Acta physiologica Sinica]. vol 74. issue 2. 2022-05-03. PMID:35503076. |
[phagocytosis of microglia in neurodegenerative diseases]. |
2022-05-03 |
2023-08-13 |
Not clear |
| Yue-Ying Liu, Tian-Shu DU, Yang Liu, Zhen Zhang, Ai-Niwaer Aizier, Xiao-Li Gong, Xiao-Min Wang, Ting Zhan. [Phagocytosis of microglia in neurodegenerative diseases]. Sheng li xue bao : [Acta physiologica Sinica]. vol 74. issue 2. 2022-05-03. PMID:35503076. |
genome-wide association studies and brain imaging studies have suggested that microglia are activated in early stage of neurodegenerative diseases. |
2022-05-03 |
2023-08-13 |
Not clear |
| Yue-Ying Liu, Tian-Shu DU, Yang Liu, Zhen Zhang, Ai-Niwaer Aizier, Xiao-Li Gong, Xiao-Min Wang, Ting Zhan. [Phagocytosis of microglia in neurodegenerative diseases]. Sheng li xue bao : [Acta physiologica Sinica]. vol 74. issue 2. 2022-05-03. PMID:35503076. |
in this review, we summarize the important roles of microglia in neurodegenerative diseases, and further analyze the functions and molecular mechanisms of microglia phagocytosis and trogocytosis. |
2022-05-03 |
2023-08-13 |
Not clear |