| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zihua Wan. Editorial: Role of microglia autophagy in age-related neurodegenerative diseases. Frontiers in aging neuroscience. vol 15. 2023-04-07. PMID:37025966. |
editorial: role of microglia autophagy in age-related neurodegenerative diseases. |
2023-04-07 |
2023-08-14 |
Not clear |
| Yiguo Qiu, Xianli Shen, Heping X. Editorial: Microglia and peripheral immune cells in aging and neurodegenerative diseases. Frontiers in cell and developmental biology. vol 11. 2023-03-31. PMID:36998247. |
editorial: microglia and peripheral immune cells in aging and neurodegenerative diseases. |
2023-03-31 |
2023-08-14 |
Not clear |
| Kaja Kasarełło, Martyna Seta, Dorota Sulejczak, Emilian Snarski, Agnieszka Cudnoch-Jędrzejewsk. Effect of Hematopoietic Stem Cell Transplantation and Post-Transplantation Cyclophosphamide on the Microglia Phenotype in Rats with Experimental Allergic Encephalomyelitis. Archivum immunologiae et therapiae experimentalis. vol 71. issue 1. 2023-03-25. PMID:36964399. |
therapies affecting the microglia phenotype may be beneficial in treating inflammatory neurodegenerative diseases. |
2023-03-25 |
2023-08-14 |
rat |
| Carla Cangalaya, Susanne Wegmann, Weilun Sun, Lisa Diez, Anna Gottfried, Karin Richter, Stoyan Stoyanov, Janelle Pakan, Klaus-Dieter Fischer, Alexander Dityate. Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy. Brain, behavior, and immunity. 2023-03-11. PMID:36906076. |
however, during neuroinflammation and neurodegenerative diseases, microglia can induce excessive synaptic loss, although the precise underlying mechanisms are unknown. |
2023-03-11 |
2023-08-14 |
Not clear |
| Anna K Bernath, Taryn E Murray, Sijie Shirley Yang, Julien Gibon, Andis Klegeri. Microglia secrete distinct sets of neurotoxins in a stimulus-dependent manner. Brain research. 2023-03-06. PMID:36878343. |
our observations contribute to a growing body of knowledge on the regulation of the microglial secretome, which may inform future development of novel therapeutics for neurodegenerative diseases, where dysregulated microglia are key contributors to pathogenesis. |
2023-03-06 |
2023-08-14 |
Not clear |
| Rita Polito, Maria Ester La Torre, Fiorenzo Moscatelli, Giuseppe Cibelli, Anna Valenzano, Maria Antonietta Panaro, Marcellino Monda, Antonietta Messina, Vincenzo Monda, Daniela Pisanelli, Francesco Sessa, Giovanni Messina, Chiara Porr. The Ketogenic Diet and Neuroinflammation: The Action of Beta-Hydroxybutyrate in a Microglial Cell Line. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36834515. |
microglial cell activation plays a key role in the development of neurodegenerative diseases, resulting in the production of several proinflammatory secondary metabolites. |
2023-02-25 |
2023-08-14 |
Not clear |
| Ya-Jing Liu, Yu Ding, Yan-Qing Yin, Hui Xiao, Gang Hu, Jia-Wei Zho. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 8. 2023-02-16. PMID:36795751. |
microglia play a critical role in the pathogenic process of neurodegenerative diseases, such as parkinson's disease (pd) and alzheimer's disease (ad). |
2023-02-16 |
2023-08-14 |
Not clear |
| Akshay Kumar Vijaya, Monika Iešmantaitė, Virginia Mela, Daiva Baltriukienė, Aurelijus Buroka. Microglia isolation from aging mice for cell culture: A beginner's guide. Frontiers in cellular neuroscience. vol 17. 2023-02-06. PMID:36744004. |
therefore, there is a need for a more efficient method to isolate pure and high-yield microglia from adult mice to study various neurodegenerative diseases. |
2023-02-06 |
2023-08-14 |
mouse |
| Fatemeh Tahmasebi, Shirin Barat. The Role of Microglial Depletion Approaches in Pathological Condition of CNS. Cellular and molecular neurobiology. 2023-02-04. PMID:36738403. |
for these reasons, the inhibition of microglia with these models was considered a therapeutic approach for neurodegenerative disease treatment. |
2023-02-04 |
2023-08-14 |
Not clear |
| Zi-Hua Song, Xiang-Jie Song, Chen-Ling Yang, Peng Cao, Yu Mao, Yan Jin, Meng-Yun Xu, Hai-Tao Wang, Xia Zhu, Wei Wang, Zhi Zhang, Wen-Juan Ta. Up-regulation of microglial chemokine CXCL12 in anterior cingulate cortex mediates neuropathic pain in diabetic mice. Acta pharmacologica Sinica. 2023-01-25. PMID:36697977. |
accumulating evidence shows that dysfunction of microglia in the central nervous system contributes to many diseases, including chronic pain and neurodegenerative diseases. |
2023-01-25 |
2023-08-14 |
mouse |
| Qi Qin, Meng Wang, Huiliang Li, Zhiqing David Xu, Yi Tan. Editorial: The role of microglia in the pathogenesis of neurodegenerative diseases. Frontiers in aging neuroscience. vol 14. 2023-01-23. PMID:36688165. |
editorial: the role of microglia in the pathogenesis of neurodegenerative diseases. |
2023-01-23 |
2023-08-14 |
Not clear |
| Mari Gotoh, Yasunori Miyamoto, Hiroko Ikeshima-Kataok. Astrocytic Neuroimmunological Roles Interacting with Microglial Cells in Neurodegenerative Diseases. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36675113. |
in this review paper, we mostly focus on the functional role of astrocytes in the extracellular matrix and on interactions between reactive astrocytes and reactive microglia in normal states and in neurodegenerative diseases, because the authors feel it is necessary to elucidate the mechanisms among activated glial cells in the pathology of neurological diseases in order to pave the way for drug discovery. |
2023-01-21 |
2023-08-14 |
human |
| Chuan-Hsiu Liu, Mei-Ying Chen, Yueh-Hsiung Kuo, Jack Cheng, Li-Zhong Chang, Meng-Shiun Chang, Tsai-Ni Chuang, Wen-Tsong Hsieh, Yan-Ru Xiao, Bor-Tsang Wu, Wei-Yong Lin, Hsin-Ping Li. Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner. Molecules (Basel, Switzerland). vol 28. issue 2. 2023-01-21. PMID:36677566. |
microglia are neuroglia in the brain with an innate immune function and participate in the progress of neurodegenerative diseases. |
2023-01-21 |
2023-08-14 |
Not clear |
| Giovanni Graziano, Pietro Delre, Francesca Carofiglio, Josè Brea, Alessia Ligresti, Magdalena Kostrzewa, Chiara Riganti, Claudia Gioè-Gallo, Maria Majellaro, Orazio Nicolotti, Nicola Antonio Colabufo, Carmen Abate, Maria Isabel Loza, Eddy Sotelo, Giuseppe Felice Mangiatordi, Marialessandra Contino, Angela Stefanachi, Francesco Leonett. N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R). European journal of medicinal chemistry. vol 248. 2023-01-19. PMID:36657299. |
in the last decade, several studies have shown that cb2r is overexpressed in activated central nervous system (cns) microglia cells, in disorders based on an inflammatory state, such as neurodegenerative diseases, neuropathic pain, and cancer. |
2023-01-19 |
2023-08-14 |
human |
| Carla Cuní-López, Romal Stewart, Anthony R White, Hazel Que. 3D in vitro modelling of human patient microglia: A focus on clinical translation and drug development in neurodegenerative diseases. Journal of neuroimmunology. vol 375. 2023-01-19. PMID:36657374. |
3d in vitro modelling of human patient microglia: a focus on clinical translation and drug development in neurodegenerative diseases. |
2023-01-19 |
2023-08-14 |
human |
| Carla Cuní-López, Romal Stewart, Anthony R White, Hazel Que. 3D in vitro modelling of human patient microglia: A focus on clinical translation and drug development in neurodegenerative diseases. Journal of neuroimmunology. vol 375. 2023-01-19. PMID:36657374. |
microglia have an increasingly well-recognised role in the pathogenesis of neurodegenerative diseases, thereby becoming attractive therapeutic targets. |
2023-01-19 |
2023-08-14 |
human |
| Carla Cuní-López, Romal Stewart, Anthony R White, Hazel Que. 3D in vitro modelling of human patient microglia: A focus on clinical translation and drug development in neurodegenerative diseases. Journal of neuroimmunology. vol 375. 2023-01-19. PMID:36657374. |
in this review, we discuss the use of 3d in vitro platforms to improve microglia modelling and their potential benefits to fast-track drug development for neurodegenerative diseases. |
2023-01-19 |
2023-08-14 |
human |
| Lijuan Zhang, Yafei Wang, Taohui Liu, Ying Mao, Bo Pen. Novel Microglia-based Therapeutic Approaches to Neurodegenerative Disorders. Neuroscience bulletin. 2023-01-02. PMID:36593381. |
we further provide a comprehensive overview of therapeutic interventions targeting microglia in neurodegenerative diseases. |
2023-01-02 |
2023-08-14 |
Not clear |
| Sheng Gao, Shu Jia, Luyue Bai, Dongru Li, Chunyang Men. Transcriptome Analysis Unveils That Exosomes Derived from M1-Polarized Microglia Induce Ferroptosis of Neuronal Cells. Cells. vol 11. issue 24. 2022-12-23. PMID:36552720. |
microglia play a vital role in neurodegenerative diseases. |
2022-12-23 |
2023-08-14 |
Not clear |
| Yoo Jin Kim, You Kyoung Shin, Eunhye Seo, Geun Hee Seo. Astrocytes Reduce Store-Operated Ca Pharmaceuticals (Basel, Switzerland). vol 15. issue 12. 2022-12-23. PMID:36558972. |
astrocytes reduce store-operated ca inflammation and loss of cholinergic transmission are involved in neurodegenerative diseases, but possible interactions between them within neurons, astrocytes, and microglia have not yet been investigated. |
2022-12-23 |
2023-08-14 |
Not clear |