| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B. Rocha, G. Di Scala, F. Jenck, J.-L. Moreau, G. Sandne. Conditioned place aversion induced by 5-HT(1C) receptor antagonists. Behavioural pharmacology. vol 4. issue 2. 2019-11-20. PMID:11224176. |
a place-conditioning procedure was used to investigate the affective properties in rats of non-selective serotonin receptor antagonists (mianserin, eltoprazine and ketanserin) differing from each other by their affinity for 5-ht(1c) and 5-ht(2) receptors among others. |
2019-11-20 |
2023-08-12 |
rat |
| A.K. Cadogan, D.A. Kendall, H. Fink, C.A. Marsde. Social interaction increases 5-HT release and cAMP efflux in the rat ventral hippocampus in vivo. Behavioural pharmacology. vol 5. issue 3. 2019-11-20. PMID:11224279. |
the results suggest that social interaction results in activation of a post-synaptic 5-ht receptor (5-ht(1a) or 5-ht(6)/5-ht(7)) coupled to adenylate cyclase but that this receptor is not responsible for the aversion-induced behaviour. |
2019-11-20 |
2023-08-12 |
rat |
| B. Bjorvatn, D. Neckelmann, A.A. Bjørkum, R. Ursi. Hypothermia and the 5-HT syndrome induced by CGS 12066B independently of 5-HT(1B) receptor activation. Behavioural pharmacology. vol 7. issue 5. 2019-11-20. PMID:11224442. |
the cgs 12066b-induced changes were not antagonized by 5-ht(1b) receptor antagonists, or antagonists at other 5-ht receptor. |
2019-11-20 |
2023-08-12 |
rat |
| C. Sánche. 5-HT(1A) receptors play an important role in modulation of behavior of rats in a two-compartment black and white box. Behavioural pharmacology. vol 7. issue 8. 2019-11-20. PMID:11224473. |
it is suggested that 5-ht(1a) and 5-ht(2c) receptors are involved in mediation of exploratory behavior in rats, and that the 5-ht receptor subtype mediated effects may modulate one another. |
2019-11-20 |
2023-08-12 |
rat |
| Kimberly L. Stark, René He. Knockout Corner. The international journal of neuropsychopharmacology. vol 2. issue 2. 2019-11-20. PMID:11281982. |
to date, there are 14 known serotonin receptor subtypes through which serotonin exerts its multiple actions. |
2019-11-20 |
2023-08-12 |
mouse |
| Klaus Peter Lesch, Armin Heil. Serotonergic gene transcriptional control regions: targets for antidepressant drug development? The international journal of neuropsychopharmacology. vol 3. issue 1. 2019-11-20. PMID:11343581. |
the formation and integration of neural networks is dependent on the actions of the master control neurotransmitter serotonin (5-ht) acting through multiple 5-ht receptor subtypes. |
2019-11-20 |
2023-08-12 |
Not clear |
| Caroline Flora Samer, Jules Alexandre Desmeules, Pierre Daye. Individualizing analgesic prescription Part I: pharmacogenetics of opioid analgesics. Personalized medicine. vol 3. issue 3. 2019-11-20. PMID:29788657. |
this two-part review summarizes the available data on the pharmacokinetic-pharmacodynamic consequences of known polymorphisms of drug-metabolizing enzymes (cyp and uridine diphosphate glucuronosyltransferase), drug transporters (multidrug resistance proteins, multidrug resistance-associated proteins, organic anion-transporting polypeptides, and serotonin transporters), relevant drug targets (such as µ-opioid receptor, serotonin receptor and cyclooxygenases) and other nonopioid biological systems, on currently prescribed central and peripheral analgesics. |
2019-11-20 |
2023-08-13 |
Not clear |
| Stefania Porcu, Stefania Demuro, Alberto Luridiana, Andrea Cocco, Angelo Frongia, David J Aitken, Florence Charnay-Pouget, Regis Guillot, Giorgia Sarais, Francesco Secc. Brønsted Acid Mediated Cascade Reaction To Access 3-(2-Bromoethyl)benzofurans. Organic letters. vol 20. issue 23. 2019-11-20. PMID:30422665. |
this mild and facile strategy was applied for the synthesis of a series of 5-ht serotonin receptor agonists, underlining its potential for the syntheses of bioactive compounds and natural products. |
2019-11-20 |
2023-08-13 |
Not clear |
| Yu-Jin Kwon, Kyung-Won Hong, Byung Jin Park, Dong-Hyuk Jun. Serotonin receptor 3B polymorphisms are associated with type 2 diabetes: The Korean Genome and Epidemiology Study. Diabetes research and clinical practice. vol 153. 2019-11-12. PMID:31152805. |
serotonin, or 5-hydroxytryptamine (5-ht), and serotonin receptor (htr) subtypes contribute to controlling energy homeostasis. |
2019-11-12 |
2023-08-13 |
Not clear |
| Meysam Amidfar, Yong-Ku Ki. Recent Developments on Future Antidepressant-related Serotonin Receptors. Current pharmaceutical design. vol 24. issue 22. 2019-11-06. PMID:30073919. |
however, paradoxical antidepressant-like effects of both agonists and antagonists at particular 5-ht receptors suggest the need to consider the neurochemical mechanisms of each 5-ht receptor subtype. |
2019-11-06 |
2023-08-13 |
Not clear |
| Andrew N Bubak, Michael J Watt, Kenneth J Renner, Abigail A Luman, Jamie D Costabile, Erin J Sanders, Jaime L Grace, John G Swallo. Sex differences in aggression: Differential roles of 5-HT2, neuropeptide F and tachykinin. PloS one. vol 14. issue 1. 2019-09-27. PMID:30695038. |
specifically, the role of 5-ht receptor subtypes are largely unknown, as is the potential interactive role of 5-ht with other neurochemical systems known to play a critical role in aggression. |
2019-09-27 |
2023-08-13 |
Not clear |
| Samantha M Meadows, Melissa M Conti, Libby Gross, Nicole E Chambers, Yarden Avnor, Corinne Y Ostock, Kathryn Lanza, Christopher Bisho. Diverse serotonin actions of vilazodone reduce l-3,4-dihidroxyphenylalanine-induced dyskinesia in hemi-parkinsonian rats. Movement disorders : official journal of the Movement Disorder Society. vol 33. issue 11. 2019-09-16. PMID:30485908. |
to date, targeting serotonin transporters or serotonin receptor subtype 1a (5-ht |
2019-09-16 |
2023-08-13 |
rat |
| Elizabeth Aaron, Alicia Montgomery, Xinguo Ren, Stephen Guter, George Anderson, Ana M D Carneiro, Suma Jacob, Matthew Mosconi, Ghanshyam N Pandey, Edwin Cook, Jeremy Veenstra-VanderWeel. Whole Blood Serotonin Levels and Platelet 5-HT Journal of autism and developmental disorders. vol 49. issue 6. 2019-08-06. PMID:30927179. |
decreased platelet serotonin receptor 5-ht |
2019-08-06 |
2023-08-13 |
Not clear |
| Cuneyt Tegin, Gulay Tegin, Rif S El-Mallak. Effective Vortioxetine Dose Varies with Extent of Antidepressant Use Across Countries. Psychopharmacology bulletin. vol 48. issue 1. 2019-07-23. PMID:29382958. |
vortioxetine is thought to work through a combination of two pharmacological modes of action: serotonin reuptake inhibition and modification of serotonin receptor activity, in a dose-dependent manner. |
2019-07-23 |
2023-08-13 |
Not clear |
| Justine Masso. Serotonin in retina. Biochimie. vol 161. 2019-07-08. PMID:30419260. |
whereas signaling pathways activated by 5-ht receptor binding has been poorly investigated so far, numerous data demonstrated that 5-ht is involved in retinal physiology, retinal physiopathology and photoreceptor survival. |
2019-07-08 |
2023-08-13 |
Not clear |
| Neil C Lax, Stacy-Ann J Parker, Edward J Hilton, Youstina Seliman, Kevin J Tidgewell, Benedict J Kolbe. Cyanobacterial extract with serotonin receptor subtype 7 (5-HT Synapse (New York, N.Y.). vol 72. issue 11. 2019-06-10. PMID:29992647. |
cyanobacterial extract with serotonin receptor subtype 7 (5-ht marine cyanobacteria represent a unique source in the field of drug discovery due to the secondary metabolites they produce and the structural similarity these compounds have to endogenous mammalian receptor ligands. |
2019-06-10 |
2023-08-13 |
Not clear |
| Wanying Li, Liuning L. [Effect of moxibustion on prevention and treatment of nausea and vomiting caused by cisplatin in lung cancer]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 38. issue 7. 2019-05-31. PMID:30014661. |
to observe the clinical effects between moxibustion combined with 5-hydroxy tryptamine (5-ht) receptor antagonist and simple 5-ht receptor antagonist in the prevention and treatment of nausea and vomiting caused by cisplatin chemotherapy in patients with lung cancer. |
2019-05-31 |
2023-08-13 |
Not clear |
| Petra Strajhar, Patrick Vizeli, Melanie Patt, Patrick C Dolder, Denise V Kratschmar, Matthias E Liechti, Alex Odermat. Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study. The Journal of steroid biochemistry and molecular biology. vol 186. 2019-05-21. PMID:30381248. |
the effects of the amphetamines on glucocorticoid production were similar to those that were previously reported for methylphenidate (60 mg) but weaker than those for the serotonin releaser 3,4-methylenedioxymethamphetamine (mdma; 125 mg) or direct serotonin receptor agonist lysergic acid diethylamide (lsd; 0.2 mg). |
2019-05-21 |
2023-08-13 |
human |
| Robin N Abbey-Lee, Emily J Uhrig, Josefina Zidar, Anna Favati, Johan Almberg, Josefin Dahlbom, Svante Winberg, Hanne Løvli. The Influence of Rearing on Behavior, Brain Monoamines, and Gene Expression in Three-Spined Sticklebacks. Brain, behavior and evolution. vol 91. issue 4. 2019-05-07. PMID:29961048. |
exposure to a simulated predator environment tended to lower expression of dopamine receptor drd4a, a complex environment increased expression of dopamine receptor drd1b, while a variable social environment tended to increase serotonin receptor 5-htr2b and serotonin transporter slc6a4a expression. |
2019-05-07 |
2023-08-13 |
Not clear |
| Karen K Y Lee, Chloe N Soutar, Hans C Dringenber. Gating of long-term potentiation (LTP) in the thalamocortical auditory system of rats by serotonergic (5-HT) receptors. Brain research. vol 1683. 2019-04-19. PMID:29325855. |
thus, we examined the role of several, predominant 5-ht receptor classes (5-ht |
2019-04-19 |
2023-08-13 |
rat |