| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W H Weintraub, P Cleveland-Wolfe, C Fewtrel. Paracrine Ca2+ signaling in vitro: serotonin-mediated cell-cell communication in mast cell/smooth muscle cocultures. Journal of cellular physiology. vol 160. issue 2. 1994-08-25. PMID:8040194. |
smooth muscle ca2+ responses were dependent on preloading mast cells with serotonin and were blocked by the 5ht2 antagonist ketanserin. |
1994-08-25 |
2023-08-12 |
Not clear |
| M R Budhoo, J M Kellu. Evidence for a 5-HT4 receptor pathway mediating chloride secretion in the rat distal colon. The Journal of surgical research. vol 57. issue 1. 1994-08-22. PMID:8041147. |
5-ht concentration response was measured in the presence and absence of the following 5-ht receptor antagonists: 10 microm 5-htp-dp (5-ht1p), 1 microm methysergide (5-ht1-like and 5-ht2), 0.1 microm ketanserin (5-ht2), 0.3 microm ondansetron (5-ht3) 0.1, 0.5, 1 and 3 microm ics 205-930 (5-ht3 and 5-ht4), and 0.1, 0.03, and 0.01 microm of the new selective 5-ht4 antagonist, sc 53606. |
1994-08-22 |
2023-08-12 |
rat |
| J K Ward, A J Fox, P J Barnes, M G Belvis. Inhibition of excitatory non-adrenergic non-cholinergic bronchoconstriction in guinea-pig airways in vitro by activation of an atypical 5-HT receptor. British journal of pharmacology. vol 111. issue 4. 1994-08-17. PMID:7518294. |
this inhibition was not significantly affected by the 5-ht2 antagonist, ketanserin (1 microm) when inhibitions (+/- ketanserin) at each concentration of 5-ht were compared by unpaired t tests; however, this concentration appeared to produce a leftward shift (approximately 10 fold) of the 5-ht concentration-inhibition curve. |
1994-08-17 |
2023-08-12 |
Not clear |
| P J Johnson, J C Bornstein, J B Furness, D J Woollard, S L Orrman-Rossite. Characterization of 5-hydroxytryptamine receptors mediating mucosal secretion in guinea-pig ileum. British journal of pharmacology. vol 111. issue 4. 1994-08-17. PMID:8032611. |
low concentrations of 5-ht (10-300 nm) evoked monophasic increases in isc which were significantly reduced by hyoscine (100 nm), tetrodotoxin (ttx, 300 nm) and the 5-ht2 receptor antagonist, ketanserin (3-300 nm). |
1994-08-17 |
2023-08-12 |
Not clear |
| M Johnson, P K Sonsalla, A A Letter, G R Hanson, J W Gib. Role of the 5-HT2 receptor in the methamphetamine-induced neurochemical alterations. The Journal of pharmacology and experimental therapeutics. vol 270. issue 1. 1994-08-15. PMID:7913500. |
the possibility that serotonin (5-ht) modulates dopamine (da) synthesis by acting at 5-ht2 receptor sites during methamphetamine (meth) treatment was investigated. |
1994-08-15 |
2023-08-12 |
Not clear |
| R C Arora, H Y Meltze. Effect of clozapine treatment on serotonin-2-receptor binding in the blood platelets of schizophrenic patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 10. issue 2. 1994-08-10. PMID:8024672. |
clozapine, but not typical neuroleptic drugs, increased kd, indicating a lower affinity of the 5-ht2 sites for 5-ht. |
1994-08-10 |
2023-08-12 |
Not clear |
| H Beele, H Thierens, L de Ridde. Dose-response curve of the effects of serotonin and ketanserin on the functional morphology of skin in vitro. Skin pharmacology : the official journal of the Skin Pharmacology Society. vol 7. issue 4. 1994-08-09. PMID:8024799. |
a cumulative dose-response curve of the effects of serotonin and its 5-ht2 receptor antagonist ketanserin in embryonic chick skin has been set up using morphological analysis and incorporation of 3h-thymidine as parameters. |
1994-08-09 |
2023-08-12 |
chicken |
| H Beele, H Thierens, L de Ridde. Dose-response curve of the effects of serotonin and ketanserin on the functional morphology of skin in vitro. Skin pharmacology : the official journal of the Skin Pharmacology Society. vol 7. issue 4. 1994-08-09. PMID:8024799. |
from the results of these experiments, we could deduce new arguments in favor of the hypothesis that a 5-ht2 receptor is involved in the effects of serotonin and ketanserin in embryonic chick skin observed in vitro. |
1994-08-09 |
2023-08-12 |
chicken |
| Y Hosoda, Y Kana. [Role of serotonin in the progression of pulmonary hypertension]. [Rinsho ketsueki] The Japanese journal of clinical hematology. vol 35. issue 4. 1994-08-09. PMID:8028183. |
to clarify the role of serotonin, the in vivo and in vitro effects of the selective 5-ht2 receptor antagonist, dv-7028, on mct-induced pulmonary hypertension were studied. |
1994-08-09 |
2023-08-12 |
rat |
| M L Cohen, K D Kurz, R W Fuller, D O Calligar. Comparative 5-HT2-receptor antagonist activity of amesergide and its active metabolite 4-hydroxyamesergide in rats and rabbits. The Journal of pharmacy and pharmacology. vol 46. issue 3. 1994-08-08. PMID:8027933. |
4-hydroxyamesergide was a potent 5-ht2-receptor antagonist with an affinity equal to or greater than amesergide under in-vitro conditions as measured by blockade of vascular 5-ht2 receptors, and 5-hydroxytryptamine (5-ht)-amplified adp-induced rabbit platelet aggregation. |
1994-08-08 |
2023-08-12 |
rat |
| M Pompeiano, J M Palacios, G Mengo. Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors. Brain research. Molecular brain research. vol 23. issue 1-2. 1994-08-08. PMID:8028479. |
distribution of the serotonin 5-ht2 receptor family mrnas: comparison between 5-ht2a and 5-ht2c receptors. |
1994-08-08 |
2023-08-12 |
rat |
| M Pompeiano, J M Palacios, G Mengo. Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors. Brain research. Molecular brain research. vol 23. issue 1-2. 1994-08-08. PMID:8028479. |
because of their similarities, serotonin 5-ht2, 5-ht1c, and the recently described 5-ht2f receptors have been classified as members of the 5-ht2 receptor family, and they have been renamed 5-ht2a, 5-ht2c and 5-ht2b, respectively. |
1994-08-08 |
2023-08-12 |
rat |
| J R Dochert. Aging and vasoconstrictor responses mediated by alpha 2-adrenoceptors and 5-HT1 and 5-HT2 receptors. Annals of the New York Academy of Sciences. vol 717. 1994-08-08. PMID:8030844. |
the potencies of noradrenaline (na) at producing alpha 2-adrenoceptor mediated contractions, and of 5-hydroxytryptamine (5-ht) at producing 5-ht1 and 5-ht2 receptor mediated contractions were investigated in rings of human saphenous vein obtained from varicose vein surgery. |
1994-08-08 |
2023-08-12 |
human |
| J R Dochert. Aging and vasoconstrictor responses mediated by alpha 2-adrenoceptors and 5-HT1 and 5-HT2 receptors. Annals of the New York Academy of Sciences. vol 717. 1994-08-08. PMID:8030844. |
there was a significant negative correlation between agonist potency and age for na at alpha 2-adrenoceptors (r = 0.52, n = 21, p < 0.05) and for 5-ht at both 5-ht1 (r = 0.47, n = 19, p < 0.05) and 5-ht2 (r = 0.54, n = 19, p < 0.05) receptors, so that both agonists were less potent with increasing age. |
1994-08-08 |
2023-08-12 |
human |
| C el Rawadi, R Haddad, M Davy, M Midol-Monnet, Y Cohe. [Role of 5-HT2 receptors in the positive chronotropic action of serotonin on the isolated atria in rats]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 187. issue 3. 1994-08-03. PMID:8019915. |
[role of 5-ht2 receptors in the positive chronotropic action of serotonin on the isolated atria in rats]. |
1994-08-03 |
2023-08-12 |
rat |
| C el Rawadi, R Haddad, M Davy, M Midol-Monnet, Y Cohe. [Role of 5-HT2 receptors in the positive chronotropic action of serotonin on the isolated atria in rats]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 187. issue 3. 1994-08-03. PMID:8019915. |
the remaining response to 5-ht was completely inhibited by the 5-ht2 antagonist ketanserin (1 microm). |
1994-08-03 |
2023-08-12 |
rat |
| N F Wiernsperge. Serotonin, 5-HT2 receptors, and their blockade by naftidrofuryl: a targeted therapy of vascular diseases. Journal of cardiovascular pharmacology. vol 23 Suppl 3. 1994-08-02. PMID:7517475. |
serotonin, 5-ht2 receptors, and their blockade by naftidrofuryl: a targeted therapy of vascular diseases. |
1994-08-02 |
2023-08-12 |
Not clear |
| N F Wiernsperge. Serotonin, 5-HT2 receptors, and their blockade by naftidrofuryl: a targeted therapy of vascular diseases. Journal of cardiovascular pharmacology. vol 23 Suppl 3. 1994-08-02. PMID:7517475. |
the importance and the various effects of serotonin (5-ht) in cardiovascular diseases are reviewed, with particular emphasis on the involvement of 5-ht2 receptors as mediators of the biological responses of vessels and blood platelets to 5-ht. |
1994-08-02 |
2023-08-12 |
Not clear |
| C M Yang, Y L Yo, J T Hsieh, R On. 5-Hydroxytryptamine receptor-mediated phosphoinositide hydrolysis in canine cultured tracheal smooth muscle cells. British journal of pharmacology. vol 111. issue 3. 1994-08-02. PMID:8019756. |
5-ht2 receptors may be predominantly mediating ips accumulation and presumably ip-induced ca2+ release may function as the transducing mechanism for 5-ht stimulated contraction of tracheal smooth muscle. |
1994-08-02 |
2023-08-12 |
Not clear |
| M Toth, T Shen. Antagonist-mediated down-regulation of 5-hydroxytryptamine type 2 receptor gene expression: modulation of transcription. Molecular pharmacology. vol 45. issue 6. 1994-08-01. PMID:7517496. |
here we show that long term treatment with serotonin or mianserin, an antagonist and antidepressant, results in reduced levels of both the 5-ht2 receptor and its rna. |
1994-08-01 |
2023-08-12 |
Not clear |