| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo Chen, Yaoxi Tan, Yan Liang, Yan Li, Lei Chen, Shuangshuang Wu, Wei Xu, Yan Wang, Weihong Zhao, Jianqing W. Per2 participates in AKT-mediated drug resistance in A549/DDP lung adenocarcinoma cells. Oncology letters. vol 13. issue 1. 2020-10-01. PMID:28123577. |
per2 knockdown and overexpression in a549/ddp cells were used to compare cell proliferation (by mtt assay), apoptosis (active-caspase 3 western blot) and clone forming assay. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yi Xiao, Taoran Deng, Changliang Su, Zhen Shan. MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS. Oncology letters. vol 13. issue 6. 2020-10-01. PMID:28599501. |
following transfection with mir-217 mimics, an mtt assay, chemosensitivity assay, cell apoptosis assay and western blot analysis were performed in aml cell lines. |
2020-10-01 |
2023-08-13 |
rat |
| Jing Shi, Xu Zhang, Taoping Shi, Hongzhao L. Antitumor effects of curcumin in human bladder cancer Oncology letters. vol 14. issue 1. 2020-10-01. PMID:28693289. |
in the present study, the effects of curcumin on cell growth, apoptosis and migration of bladder cancer cell lines were evaluated using an mtt assay, a transwell assay and flow cytometry, and the associated mechanisms were investigated using western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Zhongwei He, Xiangling Xiao, Shan Li, Yang Guo, Qiuyue Huang, Xin Shi, Xiaobo Wang, Ying Li. Oridonin induces apoptosis and reverses drug resistance in cisplatin resistant human gastric cancer cells. Oncology letters. vol 14. issue 2. 2020-10-01. PMID:28781688. |
the drug sensitivity, cell apoptosis and effects on mdr were detected by mtt assay and western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Dafei Xie, Peiwen Yuan, Dong Wang, Hua Jin, Hui Che. Effects of naringin on the expression of miR-19b and cell apoptosis in human hepatocellular carcinoma. Oncology letters. vol 14. issue 2. 2020-10-01. PMID:28789364. |
the effects of naringin on the proliferation of hepg2 cells were observed by an mtt assay, morphological changes of cells were observed by an inverted microscope, cell apoptosis was detected by dapi staining, mir-19b mrna levels were determined with rt-pcr, and the expression of bax and bcl-2 proteins was examined by western blot assay. |
2020-10-01 |
2023-08-13 |
human |
| Wei-Lung Chen, Chia-Ling Hsieh, Jiann-Hwa Chen, Chih-Sheng Huang, Wei-Ting Chen, Yu-Cheng Kuo, Cheng-Yu Chen, Fei-Ting Hs. Amentoflavone enhances sorafenib-induced apoptosis through extrinsic and intrinsic pathways in sorafenib-resistant hepatocellular carcinoma SK-Hep1 cells Oncology letters. vol 14. issue 3. 2020-10-01. PMID:28927070. |
the effects of amentoflavone on sorafenib-induced cytotoxicity and apoptosis were then investigated using mtt, flow cytometry, dna gel electrophoresis and western blot analysis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yi Shi, Wei-Zhong Wu, An Huo, Wei Zhou, Xiao-Hong Ji. Isobavachalcone inhibits the proliferation and invasion of tongue squamous cell carcinoma cells. Oncology letters. vol 14. issue 3. 2020-10-01. PMID:28928824. |
the function of ibc on tca8113 cell apoptosis and apoptosis-associated signaling pathways was determined using an mtt assay, morphological staining, annexin v-propidium iodide (pi) staining and western blot analysis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yali Gao, Zishen Zhao, Xiaoyin Meng, Hongguag Chen, Guojun F. Migration and invasion in B16-F10 mouse melanoma cells are regulated by Nrf2 inhibition during treatment with ionizing radiation. Oncology letters. vol 16. issue 2. 2020-10-01. PMID:30008889. |
small interfering (si)rnas targeting nrf2 were transfected into b16-f10 cells, and cell proliferation, invasion and apoptosis were detected by transwell, mtt or western blot assays. |
2020-10-01 |
2023-08-13 |
mouse |
| Venu Venkatarame Gowda Saralamma, Preethi Vetrivel, Seong Min Kim, Sang Eun Ha, Ho Jeong Lee, Sang Joon Lee, Young Sil Kim, Jung Eun Pak, Hye Jin Lee, Jeong Doo Heo, Gon Sup Ki. Proteome Profiling of Membrane-Free Stem Cell Components by Nano-LS/MS Analysis and Its Anti-Inflammatory Activity. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-10-01. PMID:31781269. |
the cell cytotoxicity of mfscc was measured using mtt and ldh assays, the production of nitric oxide (no) was measured by the griess assay, and the protein expression levels of inducible nitric oxide (inos) and cyclooxygenase (cox-2) were examined by western blot analysis. |
2020-10-01 |
2023-08-13 |
mouse |
| Wenxian Zheng, Shuyan Han, Shantong Jiang, Lina Pang, Xiaohong Li, Xijuan Liu, Minhua Cao, Pingping L. Multiple effects of Xihuang pill aqueous extract on the Hs578T triple-negative breast cancer cell line. Biomedical reports. vol 5. issue 5. 2020-09-30. PMID:27882217. |
first, an mtt assay was used to evaluate the anti-proliferative activity of aexhp on the hs578t cell line; furthermore, the cell cycle distribution, mitochondrial membrane potential and apoptotic rate were determined by flow cytometry, and western blot analysis was used to assess the expression of apoptosis and cell cycle regulatory proteins to investigate the mechanisms of action. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ruoting Ding, Baihui Sun, Zhongyuan Liu, Xinqiang Yao, Haiming Wang, Xing Shen, Hui Jiang, Jianting Che. Advanced Oxidative Protein Products Cause Pain Hypersensitivity in Rats by Inducing Dorsal Root Ganglion Neurons Apoptosis via NADPH Oxidase 4/c-Jun N-terminal Kinase Pathways. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:28674486. |
the mtt, flow cytometry and western blot analyses were performed in the drg neurons. |
2020-09-30 |
2023-08-13 |
rat |
| Sha Feng, Jue Liu, Biao Cheng, Aiping Deng, Hong Zhan. (-)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway. Experimental and therapeutic medicine. vol 15. issue 5. 2020-09-30. PMID:29731823. |
cell viability was assessed using an mtt assay, changes in cell morphology were observed using phase-contrast microscopy, cellular apoptosis was assessed by hoechst 33342 staining, cell proliferation was measured using a cell counting kit-8 assay, mrna levels were measured by reverse transcription-quantitative polymerase chain reaction and protein expression was assessed using western blot analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Aili Li, Qingqing Wang, Gaofeng He, Junfei Jin, Guojin Huan. DEP domain containing 1 suppresses apoptosis via inhibition of A20 expression, which activates the nuclear factor κB signaling pathway in HepG2 cells. Oncology letters. vol 16. issue 1. 2020-09-30. PMID:29963168. |
cell proliferation was examined using an mtt assay and apoptosis was analyzed via detection of the apoptotic marker caspase-3 using western blot analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shuna Yao, Yanyan Liu, Zhihua Yao, Yan Zhao, Haiying Wang, Yuanlin Xu, Jiuyang Zhang, Jing Li, Shujun Yan. MicroRNA-376a regulates cell proliferation and apoptosis by targeting forkhead box protein P2 in lymphoma. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30127911. |
the expression of mir-376a in lymphoma issue and cells was detected by reverse transcription quantitative polymerase chain reaction (rt-qpcr), the expression of forkhead box protein p2 (foxp2) was detected by rt-qpcr and western blot analysis, and the effect of mir-376a on cell proliferation and apoptosis were studied by an mtt assay and flow cytometry, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Li Zhao, Xue Rong Yang, Xu Ha. MicroRNA-146b induces the PI3K/Akt/NF-κB signaling pathway to reduce vascular inflammation and apoptosis in myocardial infarction by targeting PTEN. Experimental and therapeutic medicine. vol 17. issue 2. 2020-09-30. PMID:30679990. |
an mtt assay, annexin v/propidium iodide (pi) apoptosis assay, elisa kits, western blot analysis and a caspase-3/8 activity assay were used to measure cell growth, vascular apoptosis inflammatory factors, and the b-cell lymphoma 2-associated x protein (bax), phosphatase and tensin homolog (pten), phosphoinositide 3-kinase (pi3k)/akt/nuclear factor (nf)-κb signaling pathway. |
2020-09-30 |
2023-08-13 |
rat |
| Evelyn Saba, Dahye Jeong, Muhammad Irfan, Yuan Yee Lee, Sang-Joon Park, Chae-Kyu Park, Man Hee Rhe. Anti-Inflammatory Activity of Rg3-Enriched Korean Red Ginseng Extract in Murine Model of Sepsis. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-09-29. PMID:30405742. |
we employed nitric oxide assay (no) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, quantitative reverse transcriptase-polymerase chain reaction (qrt-pcr), western blot, and hematoxylin and eosin staining (h&e) to elucidate the anti-inflammatory activity of rg3-rge. |
2020-09-29 |
2023-08-13 |
Not clear |
| Kun Qi, Jianke Zhon. LncRNA HOTAIR improves diabetic cardiomyopathy by increasing viability of cardiomyocytes through activation of the PI3K/Akt pathway. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30542437. |
hotair expression vector was transfected into cells of ac16 cell line and the effects of hotair overexpression on cell viability and akt phosphorylation were detected by mtt assay and western blot analysis, respectively. |
2020-09-29 |
2023-08-13 |
human |
| Meng Wang, Guoyue Lv, Chao Jiang, Shuli Xie, Guangyi Wan. miR-302a inhibits human HepG2 and SMMC-7721 cells proliferation and promotes apoptosis by targeting MAP3K2 and PBX3. Scientific reports. vol 9. issue 1. 2020-09-29. PMID:30765768. |
in addition, an increased mir-302a level in hepg2 cells and smmc-7721 cells were achieved through transfection with mir-302a mimics, and the effects on hepg2 cell and smmc-7721 cell proliferation, apoptosis and mapk pathways were determined using mtt, flow cytometry, qpcr and western blot assays. |
2020-09-29 |
2023-08-13 |
human |
| Changjun Yun, Wenjie Qian, Junyi Wu, Chenxi Yuan, Songzhou Jiang, Jinpeng L. Pilose antler peptide promotes osteoblast proliferation, differentiation and mineralization via the insulin signaling pathway. Experimental and therapeutic medicine. vol 19. issue 2. 2020-09-28. PMID:32010253. |
to determine whether pap can promote osteoblast development and to elucidate the molecular mechanisms underlying its functions, the present study investigated the effects of pap on osteoblast proliferation, differentiation and mineralization, and the role of the insulin signaling pathway using mtt assay, alkaline phosphatase activity assay, western blot analysis and reverse transcription-quantitative pcr. |
2020-09-28 |
2023-08-13 |
Not clear |
| Ying Wen, Xiaoyan Cai, Shaolian Chen, Wei Fu, Dong Chai, Huainian Zhang, Yongli Zhan. 7-Methoxy-1-Tetralone Induces Apoptosis, Suppresses Cell Proliferation and Migration in Hepatocellular Carcinoma via Regulating c-Met, p-AKT, NF-κB, MMP2, and MMP9 Expression. Frontiers in oncology. vol 10. 2020-09-28. PMID:32117722. |
mtt assay assessed hcc cell viability; cell apoptosis of hcc cells was determined by flow cytometry; wound healing assay evaluated hcc cell migratory ability; protein expression levels were assessed using western blot assay; the |
2020-09-28 |
2023-08-13 |
Not clear |