| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U Krause, M Nink, A Brauer, I Huber, A Velten, H Lehnert, J Beye. Studies on facial temperature rise and involvement of serotonin in the respiratory stimulation by CRH. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 23. issue 10. 1992-02-07. PMID:1761282. |
administration of 100 micrograms hcrh in 10 healthy subjects pretreated with the serotonin antagonist cyproheptadine. |
1992-02-07 |
2023-08-11 |
human |
| U Krause, M Nink, A Brauer, I Huber, A Velten, H Lehnert, J Beye. Studies on facial temperature rise and involvement of serotonin in the respiratory stimulation by CRH. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 23. issue 10. 1992-02-07. PMID:1761282. |
serum serotonin levels did not change after crh stimulation in doses up to 3 micrograms/kg body weight), and cyproheptadine did not abolish the respiratory stimulation effect of hcrh in a dosage sufficient to suppress crh.-induced cortisol secretion. |
1992-02-07 |
2023-08-11 |
human |
| C Caponnetto, M Del Sette, M Furlan, C Gandolfo, G L Mancardi, A Schenone, C Loe. Protective effect of cyproheptadine in a gerbil model of cerebral ischemia. Italian journal of neurological sciences. vol 12. issue 3 Suppl 11. 1992-01-31. PMID:1757225. |
the efficacy of cyproheptadine, a serotonin antagonist, in preventing the cerebral ischemic damage was tested on experimental model of transient global cerebral ischemia in mongolian gerbil. |
1992-01-31 |
2023-08-11 |
Not clear |
| N A Abbas, C Taube, R Hirschelmann, H J Mes. Thromboxane plasma level in kappa-carrageenin-induced acronecrosis of the tail in rats. Biomedica biochimica acta. vol 50. issue 7. 1992-01-31. PMID:1759973. |
heparin inhibited txb2 formation and acronecrosis frequency while the serotonin antagonist cyproheptadine decreased only the acronecrosis frequency but caused no change in txb2 plasma level. |
1992-01-31 |
2023-08-11 |
rat |
| J C Remus, J D Firma. Efficacy of lateral ventricular injection of epinephrine, cyproheptadine, or adenosine triphosphate on feed intake in thiamin-deficient turkeys. Poultry science. vol 70. issue 11. 1992-01-29. PMID:1754549. |
adenosine triphosphate, epinephrine, and cyproheptadine (5-ht antagonist) were injected into the lateral ventricle of td and control birds. |
1992-01-29 |
2023-08-11 |
Not clear |
| B Silvestrini, M Palmery, F Basta, P Valer. Facilitating effect of amphetamine on the response of rabbit aortic strips to adrenaline, dopamine and serotonin. Journal of neural transmission. General section. vol 86. issue 1. 1992-01-24. PMID:1751029. |
cyproheptadine inhibited the direct response to serotonin and amphetamine, and the amphetamine-facilitated response to serotonin; it was inactive against dopamine and adrenaline both alone and combined with a facilitating dose of amphetamine or serotonin. |
1992-01-24 |
2023-08-11 |
rabbit |
| G S Spencer, P Dobbie, J J Bas. Neuroendocrine regulation of growth hormone secretion in sheep. III. Serotoninergic systems. Domestic animal endocrinology. vol 8. issue 3. 1992-01-17. PMID:1684145. |
the serotonin antagonist, cyproheptadine, failed to affect gh concentrations when given either intravenously (0.25 mg/kg/h) or intracerebroventricularly (4 mg). |
1992-01-17 |
2023-08-11 |
Not clear |
| G S Spencer, P Dobbie, J J Bas. Neuroendocrine regulation of growth hormone secretion in sheep. III. Serotoninergic systems. Domestic animal endocrinology. vol 8. issue 3. 1992-01-17. PMID:1684145. |
neither serotonin nor cyproheptadine had any significant effect on plasma glucose or cortisol levels when administered icv. |
1992-01-17 |
2023-08-11 |
Not clear |
| N L Alsip, P D Harri. Receptor mediation of microvascular responses to serotonin in striated muscle. The American journal of physiology. vol 261. issue 5 Pt 2. 1991-12-23. PMID:1951740. |
serotonin, applied topically, caused a constriction of large (a1) arterioles that was attenuated by cyproheptadine, methysergide, and ly 53857 but not by mdl 7222, phentolamine, propranolol, or diphenhydramine. |
1991-12-23 |
2023-08-11 |
rat |
| N L Alsip, P D Harri. Receptor mediation of microvascular responses to serotonin in striated muscle. The American journal of physiology. vol 261. issue 5 Pt 2. 1991-12-23. PMID:1951740. |
in addition, 5-ht caused a dilation of small (a3 or a4) arterioles that was blocked by cyproheptadine and methysergide but not by ly 53857, mdl 7222, phentolamine, or propranolol. |
1991-12-23 |
2023-08-11 |
rat |
| A Verma, S K Kulkarn. Dopamine receptor mediated hypothermic action of B-HT 920 in rats. The Journal of pharmacy and pharmacology. vol 43. issue 6. 1991-11-08. PMID:1681056. |
neither the selective alpha 2-adrenoceptor antagonists, yohimbine (1 mg kg-1) or idazoxan (1 mg kg-1), the histamine antagonist mepyramine (10 mg kg-1) nor the 5-ht antagonist cyproheptadine (5 mg kg-1) inhibited b-ht 920-induced hypothermia. |
1991-11-08 |
2023-08-11 |
rat |
| T Yamamoto, E A Walker, J H Wood. Agonist and antagonist properties of serotonergic compounds in pigeons trained to discriminate either quipazine or L-5-hydroxytryptophan. The Journal of pharmacology and experimental therapeutics. vol 258. issue 3. 1991-10-17. PMID:1890629. |
the serotonin (5-ht) receptor-related compounds metergoline, pirenperone, ketanserin, cyproheptadine, pizotyline, methysergide, lysergic acid diethylamide, mianserin and cinanserin were studied in pigeons trained to discriminate l-5-hydroxytryptophan (l-5-htp) (18.0 mg/kg) from saline and in pigeons trained to discriminate quipazine (1.0 mg/kg) from saline. |
1991-10-17 |
2023-08-11 |
rat |
| G M Somoza, R E Pete. Effects of serotonin on gonadotropin and growth hormone release from in vitro perifused goldfish pituitary fragments. General and comparative endocrinology. vol 82. issue 1. 1991-09-20. PMID:1874380. |
the stimulatory effects of 5-ht on gonadotropin release could be blocked by ketanserin and cyproheptadine; however, these two antagonists had no effects on 5-ht inhibition of growth hormone release. |
1991-09-20 |
2023-08-11 |
Not clear |
| M L Evans, M J Kadan, P R Hartig, D O Carpente. Correlation of 125I-LSD autoradiographic labeling with serotonin voltage clamp responses in Aplysia neurons. Synapse (New York, N.Y.). vol 8. issue 1. 1991-09-16. PMID:1714633. |
this binding was blocked by micromolar concentrations of serotonin and lower concentrations of the serotonergic antagonists, cyproheptadine and mianserin (kadan and hartig, 1988). |
1991-09-16 |
2023-08-11 |
aplysia |
| M L Evans, M J Kadan, P R Hartig, D O Carpente. Correlation of 125I-LSD autoradiographic labeling with serotonin voltage clamp responses in Aplysia neurons. Synapse (New York, N.Y.). vol 8. issue 1. 1991-09-16. PMID:1714633. |
cells l3 and l6 have a k+ conductance increase in response to serotonin that is not blocked by cyproheptadine or mianserin. |
1991-09-16 |
2023-08-11 |
aplysia |
| M L Evans, M J Kadan, P R Hartig, D O Carpente. Correlation of 125I-LSD autoradiographic labeling with serotonin voltage clamp responses in Aplysia neurons. Synapse (New York, N.Y.). vol 8. issue 1. 1991-09-16. PMID:1714633. |
cells l2 and l4 have a biphasic response to serotonin: a na+ conductance increase, which can be blocked by cyproheptadine and mianserin, followed by a voltage dependent ca2+ conductance which is blocked by co2+ but not the serotonergic antagonists. |
1991-09-16 |
2023-08-11 |
aplysia |
| M J Sumne. Characterization of the 5-HT receptor mediating endothelium-dependent relaxation in porcine vena cava. British journal of pharmacology. vol 102. issue 4. 1991-08-28. PMID:1855122. |
the endothelium-dependent relaxation induced by 5-ht or alpha-methyl-5-ht was antagonized by methysergide, methiothepin, cyproheptadine and metergoline, but not by ketanserin, spiperone, ondansetron, verapamil, cyanopindolol, mesulergine, ics 205-930, or indomethacin. |
1991-08-28 |
2023-08-11 |
Not clear |
| G Boschi, N Launay, R Rip. Facilitation of amphetamine-induced hypothermia in mice by GABA agonists and CCK-8. British journal of pharmacology. vol 102. issue 4. 1991-08-28. PMID:1855128. |
neither the 5-hydroxytryptamine (5-ht) receptor blocker, cyproheptadine, nor the inhibitor of 5-ht synthesis, p-chlorophenylalanine (pcpa), modified dopamine-induced hypothermia. |
1991-08-28 |
2023-08-11 |
mouse |
| H Fink, R Morgenstern, T Ot. 2-Bromolisuride, an ergot derivative, with dopamine antagonistic and serotonin agonistic properties. Pharmacology, biochemistry, and behavior. vol 38. issue 2. 1991-07-31. PMID:1905409. |
the potentiating effect of 2-bromolisuride was completely blocked by the serotonin antagonists cyproheptadine and ritanserin. |
1991-07-31 |
2023-08-11 |
rat |
| A L López de Pablo, E J Marco, J M Benito, M L Fraile, M L Sanz, M J Moreno, M V Cond. Response of isolated cat middle cerebral artery to platelets: effect of endothelium removal. General pharmacology. vol 22. issue 2. 1991-07-31. PMID:2055430. |
the contractile response to platelets and serotonin under resting tension was blocked in the same way by ketanserin, methysergide or cyproheptadine. |
1991-07-31 |
2023-08-11 |
cat |