| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min-Young Noh, Kwangwoo Chun, Byung Yong Kang, Heejaung Kim, Ji-Seon Park, Han-Chang Lee, Young-Ha Kim, Saekwang Ku, Seung Hyun Ki. Newly developed glycogen synthase kinase-3 (GSK-3) inhibitors protect neuronal cells death in amyloid-beta induced cell model and in a transgenic mouse model of Alzheimer's disease. Biochemical and biophysical research communications. vol 435. issue 2. 2013-08-06. PMID:23632329. |
in particular, 50 mg/kg c-7a treated mice significantly decreased the level of phosphorylated tau (ser396) in brain hippocampus. |
2013-08-06 |
2023-08-12 |
mouse |
| S Duke Han, Jonathan Gruhl, Laurel Beckett, Hiroko H Dodge, Nikki H Stricker, Sarah Farias, Dan Munga. Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer's Disease. Brain imaging and behavior. vol 6. issue 4. 2013-08-02. PMID:22648764. |
we examined temporal relations among four classes of biomarkers: csf aβ, csf tau, neuroimaging variables (hippocampal volume, ventricular volume, fdg pet), and cognitive variables (memory and executive function). |
2013-08-02 |
2023-08-12 |
Not clear |
| Chuang Guo, Pu Wang, Man-Li Zhong, Tao Wang, Xue-Shi Huang, Jia-Yi Li, Zhan-You Wan. Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain. Neurochemistry international. vol 62. issue 2. 2013-07-22. PMID:23262393. |
deferoxamine inhibits iron induced hippocampal tau phosphorylation in the alzheimer transgenic mouse brain. |
2013-07-22 |
2023-08-12 |
mouse |
| Reisuke H Takahashi, Estibaliz Capetillo-Zarate, Michael T Lin, Teresa A Milner, Gunnar K Goura. Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. PloS one. vol 8. issue 1. 2013-07-22. PMID:23372648. |
we previously provided evidence for early co-localization of aβ42 peptides and hyperphosphorylated tau within postsynaptic terminals of ca1 dendrites in the hippocampus of ad transgenic mice. |
2013-07-22 |
2023-08-12 |
mouse |
| Cassia R Overk, Sylvia E Perez, Chunqi Ma, Matthew D Taves, Kiran K Soma, Elliott J Mufso. Sex steroid levels and AD-like pathology in 3xTgAD mice. Journal of neuroendocrinology. vol 25. issue 2. 2013-07-12. PMID:22889357. |
the age-related increase in hippocampal testosterone levels correlated positively with increases in the conformational tau isoform, alz50. |
2013-07-12 |
2023-08-12 |
mouse |
| Larry D Sparks, Richard J Kryscio, John C Hunsake. Early age-related progression of AD-like neuropathology in Down's syndrome. American journal of neurodegenerative disease. vol 2. issue 2. 2013-07-11. PMID:23844336. |
50 μm vibratome sections of formalin fixed hippocampal formations were immunohistochemically stained for amyloid-β (6e10), app (22c11) and phosphorylated tau (at8) using standard methods. |
2013-07-11 |
2023-08-12 |
human |
| Linn Hege Nilsen, Caroline Rae, Lars M Ittner, Jürgen Götz, Ursula Sonnewal. Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 5. 2013-06-28. PMID:23340677. |
overall, we revealed that astrocytes as well as glutamatergic and gabaergic neurons in the cortex of pr5 mice were in a hypermetabolic state, whereas in the hippocampus, where expression levels of mutant human tau are the highest, glutamate homeostasis was impaired. |
2013-06-28 |
2023-08-12 |
mouse |
| Lei Wang, Anne M Fagan, Aarti R Shah, Mirza Faisal Beg, John G Csernansky, John C Morris, David M Holtzma. Cerebrospinal fluid proteins predict longitudinal hippocampal degeneration in early-stage dementia of the Alzheimer type. Alzheimer disease and associated disorders. vol 26. issue 4. 2013-06-26. PMID:22156755. |
the present study was conducted to assess the relationship between csf aβ and tau protein levels and longitudinal measures of hippocampal structure in individuals with and without very mild dementia of the alzheimer type. |
2013-06-26 |
2023-08-12 |
Not clear |
| Bruno M Jedynak, Andrew Lang, Bo Liu, Elyse Katz, Yanwei Zhang, Bradley T Wyman, David Raunig, C Pierre Jedynak, Brian Caffo, Jerry L Princ. A computational neurodegenerative disease progression score: method and results with the Alzheimer's disease Neuroimaging Initiative cohort. NeuroImage. vol 63. issue 3. 2013-06-25. PMID:22885136. |
the group of biomarkers comprising the volume of the hippocampus and the protein concentration amyloid beta and tau were next in the timeline, and these were followed by three cognitive biomarkers. |
2013-06-25 |
2023-08-12 |
human |
| Dávid Lendvai, Markus Morawski, László Négyessy, Georgina Gáti, Carsten Jäger, Gábor Baksa, Tibor Glasz, Johannes Attems, Heikki Tanila, Thomas Arendt, Tibor Harkany, Alán Alpá. Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease. Acta neuropathologica. vol 125. issue 2. 2013-06-25. PMID:22961619. |
we demonstrate, by combining biochemical profiling and neuroanatomy in alzheimer's patients and transgenic (apde9) mice, the preserved turnover and distribution of axonal coats around functional synapses along dendrite segments containing hyperphosphorylated tau and in amyloid-β-laden hippocampal microdomains. |
2013-06-25 |
2023-08-12 |
mouse |
| Maria Luisa Rocco, Andrea Pristerà, Luana Pistillo, Luigi Aloe, Nadia Canu, Luigi Mann. Brain cholinergic markers and Tau phosphorylation are altered in experimental type 1 diabetes: normalization by electroacupuncture. Journal of Alzheimer's disease : JAD. vol 33. issue 3. 2013-06-25. PMID:23001708. |
here we assessed the variations of ngf and tau phosphorylation in the cortex and hippocampus, as well as the expression of choline acetyltransferase in the basal forebrain following diabetes induction and ea in adult rats. |
2013-06-25 |
2023-08-12 |
rat |
| Kevin F Bieniek, Melissa E Murray, Nicola J Rutherford, Monica Castanedes-Casey, Mariely DeJesus-Hernandez, Amanda M Liesinger, Matthew C Baker, Kevin B Boylan, Rosa Rademakers, Dennis W Dickso. Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion. Acta neuropathologica. vol 125. issue 2. 2013-06-25. PMID:23053135. |
increased tau pathology in ftld-c9orf72 was assessed with thioflavin-s fluorescent microscopy-based neurofibrillary tangle counts and with image analysis of tau burden in temporal cortex and hippocampus. |
2013-06-25 |
2023-08-12 |
Not clear |
| Bo Cui, Ming Quan Wu, Li Xing Zhu, Xiao Jun She, Qiang Ma, Hong Tao Li. Effect of chronic noise exposure on expression of N-methyl-D-aspartic acid receptor 2B and Tau phosphorylation in hippocampus of rats. Biomedical and environmental sciences : BES. vol 26. issue 3. 2013-06-11. PMID:23425798. |
effect of chronic noise exposure on expression of n-methyl-d-aspartic acid receptor 2b and tau phosphorylation in hippocampus of rats. |
2013-06-11 |
2023-08-12 |
rat |
| Bo Cui, Ming Quan Wu, Li Xing Zhu, Xiao Jun She, Qiang Ma, Hong Tao Li. Effect of chronic noise exposure on expression of N-methyl-D-aspartic acid receptor 2B and Tau phosphorylation in hippocampus of rats. Biomedical and environmental sciences : BES. vol 26. issue 3. 2013-06-11. PMID:23425798. |
to study the effect of chronic noise exposure on expression of n-methyl-d-aspartic acid receptor 2b (nr2b) and tau phosphorylation in hippocampus of rats. |
2013-06-11 |
2023-08-12 |
rat |
| Kiren Ubhi, Eliezer Maslia. Alzheimer's disease: recent advances and future perspectives. Journal of Alzheimer's disease : JAD. vol 33 Suppl 1. 2013-06-06. PMID:22810100. |
neuropathologically, ad is characterized by the progressive loss of basal forebrain cholinergic neurons that innervate the hippocampus and cortex and the abnormal extracellular accumulation of amyloid-β and intracellular tau protein. |
2013-06-06 |
2023-08-12 |
Not clear |
| M R Carratù, C Marasco, A Signorile, C Scuderi, L Steard. Are retinoids a promise for Alzheimer's disease management? Current medicinal chemistry. vol 19. issue 36. 2013-06-03. PMID:23092137. |
the ability of retinoids to exert antioxidant effects, inhibit amyloid-β (aβ) deposits and likely aβ-induced mitochondrial dysfunction, tau hyperphosphorylation, aβ-induced il6 production and neuroinflammation, increase survival in hippocampal neurons, and reverse cognitive deficits in animal models of alzheimer's disease (ad) is discussed. |
2013-06-03 |
2023-08-12 |
Not clear |
| Xiangdong Qu, Chengshi Xu, Hui Wang, Jie Xu, Weiran Liu, Yun Wang, Xingyuan Jia, Zhongcong Xie, Zhipeng Xu, Chao Ji, Anshi Wu, Yun Yu. Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:23070469. |
expression levels of glast, glt-1, nmdar1, nmdar2a/b, ampar and tau in hippocampus were assessed via quantitative western blotting. |
2013-05-29 |
2023-08-12 |
rat |
| Xiangdong Qu, Chengshi Xu, Hui Wang, Jie Xu, Weiran Liu, Yun Wang, Xingyuan Jia, Zhongcong Xie, Zhipeng Xu, Chao Ji, Anshi Wu, Yun Yu. Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:23070469. |
we found a continuous raised hippocampal glutamate and an up-regulation of glast rather than glt-1, nmdar1, nmdar2a/b, ampar or tau in hippocampus of aged rats associated with isoflurane-induced learning/memory impairment. |
2013-05-29 |
2023-08-12 |
rat |
| Leonardo C de Souza, Marie Chupin, Foudil Lamari, Claude Jardel, Delphine Leclercq, Olivier Colliot, Stéphane Lehéricy, Bruno Dubois, Marie Sarazi. CSF tau markers are correlated with hippocampal volume in Alzheimer's disease. Neurobiology of aging. vol 33. issue 7. 2013-05-27. PMID:21489655. |
csf tau markers are correlated with hippocampal volume in alzheimer's disease. |
2013-05-27 |
2023-08-12 |
Not clear |
| Leonardo C de Souza, Marie Chupin, Foudil Lamari, Claude Jardel, Delphine Leclercq, Olivier Colliot, Stéphane Lehéricy, Bruno Dubois, Marie Sarazi. CSF tau markers are correlated with hippocampal volume in Alzheimer's disease. Neurobiology of aging. vol 33. issue 7. 2013-05-27. PMID:21489655. |
in ad patients, antemortem mri hippocampal volumes (hvs) correlate with the density of neurofibrillary tangles (but not with senile plaques) at autopsy suggesting that hvs may better correlate with csf tau and hyperphosphorylated tau (p-tau) levels than csf amyloid beta protein (aβ)(42) level. |
2013-05-27 |
2023-08-12 |
Not clear |